1,465 research outputs found
Next-to-next-to-leading-order epsilon expansion for a Fermi gas at infinite scattering length
We extend previous work on applying the epsilon-expansion to universal
properties of a cold, dilute Fermi gas in the unitary regime of infinite
scattering length. We compute the ratio xi = mu/epsilon_F of chemical potential
to ideal gas Fermi energy to next-to-next-to-leading order (NNLO) in
epsilon=4-d, where d is the number of spatial dimensions. We also explore the
nature of corrections from the order after NNLO.Comment: 28 pages, 14 figure
Models of G-spectra as presheaves of spectra
Let G be a finite group. We give Quillen equivalent models for the category
of G-spectra as categories of spectrally enriched functors from explicitly
described domain categories to nonequivariant spectra. Our preferred model is
based on equivariant infinite loop space theory applied to elementary
categorical data. It recasts equivariant stable homotopy theory in terms of
point-set level categories of G-spans and nonequivariant spectra. We also give
a more topologically grounded model based on equivariant Atiyah duality.Comment: 38 pages. v4. A number of relatively small changes and corrections.
The introduction has been rewritten in response to suggestions from a
referee. To make this paper more self-contained, section 4 on enriched model
categories of G-spectra has been added. A new section 5 addresses a minor
error in the previous version
Critical Exponents of the pure and random-field Ising models
We show that current estimates of the critical exponents of the
three-dimensional random-field Ising model are in agreement with the exponents
of the pure Ising system in dimension 3 - theta where theta is the exponent
that governs the hyperscaling violation in the random case.Comment: 9 pages, 4 encapsulated Postscript figures, REVTeX 3.
Inhibition of pancreatic cancer cell growth in vitro by the tyrphostin group of tyrosine kinase inhibitors.
Tyrphostins are a group of low molecular weight synthetic inhibitors of protein tyrosine kinases (PTK). The intracellular domains of the receptors for epidermal growth factor (EGF), transforming growth factor-alpha (TGF-alpha), insulin-like growth factor 1 (IGF-1) possess PTK activity. Since EGF, TGF-alpha and IGF-1 are considered to play an important role in the proliferation of pancreatic cancer cells, we studied the effects of tyrphostins on the growth of three human pancreatic cancer cell lines (MiaPaCa-2, Panc-1 and CAV). The tyrphostins AG17, T23 and T47 all inhibited EGF and serum-stimulated DNA synthesis. AG17 was found to be the most potent of these agents and caused a dose-dependent but reversible inhibition of cell growth. Furthermore using an immunoblotting procedure we also found AG17 to inhibit EGF-induced tyrosine phosphorylation in the MiaPaCa-2 cell line. Tyrosine kinase inhibitors may prove to be useful agents for the treatment of pancreatic cancer
Human pancreatic cancer cell lines do not express receptors for somatostatin.
The in vivo administration of somatostatin (SS) or its analogues is capable of suppressing the growth of pancreatic cancer in experimental animals. We examined the effects of SS-14 and its analogue RC-160 on the in vitro growth of two human pancreatic cancer cell lines MiaPaCa-2 and Panc-1 stimulated with epidermal growth factor (EGF) or insulin-like growth factor 1 (IGF-1). Neither SS-14 nor RC-160 inhibited the growth of either cell line. In contrast RC-160 did inhibit the EGF-stimulated growth of a rat pancreatic cancer cell line AR42J. Binding studies with 125I-Tyr11 somatostatin revealed the presence of a single class of high affinity binding sites with a Kd of 0.20 +/- 0.05 nM and a Bmax of 2.1 +/- 0.26 pmoles mg-1 protein on AR42J but not displaceable binding was observed on MiaPaCa-2 or Panc-1. We conclude that lack of receptors accounts for the failure of SS-14 and RC-160 to influence the growth of human pancreatic cancer in vitro. These results, taken together with other findings, lead us to question the therapeutic efficacy of somatostatin and its analogues as mono-therapy in the treatment of human pancreatic cancer
Quantum phase transitions in the J-J' Heisenberg and XY spin-1/2 antiferromagnets on square lattice: Finite-size scaling analysis
We investigate the critical parameters of an order-disorder quantum phase
transitions in the spin-1/2 Heisenberg and XY antiferromagnets on square
lattice. Basing on the excitation gaps calculated by exact diagonalization
technique for systems up to 32 spins and finite-size scaling analysis we
estimate the critical couplings and exponents of the correlation length for
both models. Our analysis confirms the universal critical behavior of these
quantum phase transitions: They belong to 3D O(3) and 3D O(2) universality
classes, respectively.Comment: 7 pages, 3 figure
Identification sĂ©rologique rapide de Clostridium perfringens par une microtechnique dâimmunodiffusion sur lame
Guillou J.-P., Chevrier L. Identification sĂ©rologique rapide de Clostridium perfringens par une microtechnique dâimmunodiffusion sur lame. In: Bulletin de l'AcadĂ©mie VĂ©tĂ©rinaire de France tome 125 n°5, 1972. pp. 239-249
The DICE calibration project: design, characterization, and first results
We describe the design, operation, and first results of a photometric
calibration project, called DICE (Direct Illumination Calibration Experiment),
aiming at achieving precise instrumental calibration of optical telescopes. The
heart of DICE is an illumination device composed of 24 narrow-spectrum,
high-intensity, light-emitting diodes (LED) chosen to cover the
ultraviolet-to-near-infrared spectral range. It implements a point-like source
placed at a finite distance from the telescope entrance pupil, yielding a flat
field illumination that covers the entire field of view of the imager. The
purpose of this system is to perform a lightweight routine monitoring of the
imager passbands with a precision better than 5 per-mil on the relative
passband normalisations and about 3{\AA} on the filter cutoff positions. The
light source is calibrated on a spectrophotometric bench. As our fundamental
metrology standard, we use a photodiode calibrated at NIST. The radiant
intensity of each beam is mapped, and spectra are measured for each LED. All
measurements are conducted at temperatures ranging from 0{\deg}C to 25{\deg}C
in order to study the temperature dependence of the system. The photometric and
spectroscopic measurements are combined into a model that predicts the spectral
intensity of the source as a function of temperature. We find that the
calibration beams are stable at the level -- after taking the slight
temperature dependence of the LED emission properties into account. We show
that the spectral intensity of the source can be characterised with a precision
of 3{\AA} in wavelength. In flux, we reach an accuracy of about 0.2-0.5%
depending on how we understand the off-diagonal terms of the error budget
affecting the calibration of the NIST photodiode. With a routine 60-mn
calibration program, the apparatus is able to constrain the passbands at the
targeted precision levels.Comment: 25 pages, 27 figures, accepted for publication in A&
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