Individual employment histories and subsequent cause specific hospital admissions and mortality: a prospective study of a cohort of male and female workers with 21 years follow up

It is a widely held view that the labour market is demanding increased levels of flexibility, and that this is causing greater psychosocial stress among employees.1 Such stress may affect health, either through neuroendocrine pathways, or through increases in behaviours linked with poor health.2 Previously we presented evidence linking an unstable employment history, as measured by a greater number of job changes and shorter duration of current job, with a greater prevalence of smoking and greater alcohol consumption, in male and female workers.3 4 Despite this, we did not observe clear detrimental effects of such instability on health related physiological measures (body mass index, diastolic blood pressure, cholesterol, and lung function), nor on current cardiovascular health (electrocardiogram determined ischaemia and reported symptoms of angina). Finding work is easier for healthy persons, and those persons who need to find work repeatedly will be particularly likely to drop out of the workforce if their health deteriorates. Consequently, an occupational cohort, upon which our previous work was based, is least likely to include people of poor health with an unstable work history. If such people are underrepresented, attempts to determine the association between health and individual work histories will mislead. This study links the same cohort to information on the hospitalisations and deaths experienced over a 21 year follow up period. While those people whose health deteriorated before the enrolment of this cohort must remain poorly represented, these prospective data permit unbiased observation of those cases who experienced ill health subsequently, whether or not this resulted in an exit from the workforce. We hypothesise that an employment history characterised by frequent job changes, whatever the motivation for those changes, will require the person to be more focused on work, and less focused on maintaining personal health, with consequent poorer health for such people

Psychological stress and cardiovascular disease: empirical demonstration of bias in a prospective observational study of Scottish men

Objectives: To examine the association between self perceived psychological stress and cardiovascular disease in a population where stress was not associated with social disadvantage. Design: Prospective observational study with follow up of 21 years and repeat screening of half the cohort 5 years from baseline. Measures included perceived psychological stress, coronary risk factors, self reported angina, and ischaemia detected by electrocardiography. Setting: 27 workplaces in Scotland. Participants: 5606 men (mean age 48 years) at first screening and 2623 men at second screening with complete data on all measures Main outcome measures: Prevalence of angina and ischaemia at baseline, odds ratio for incident angina and ischaemia at second screening, rate ratios for cause specific hospital admission, and hazard ratios for cause specific mortality. Results: Both prevalence and incidence of angina increased with increasing perceived stress (fully adjusted odds ratio for incident angina, high versus low stress 2.66, 95% confidence interval 1.61 to 4.41; P for trend <0.001). Prevalence and incidence of ischaemia showed weak trends in the opposite direction. High stress was associated with a higher rate of admissions to hospital generally and for admissions related to cardiovascular disease and psychiatric disorders (fully adjusted rate ratios for any general hospital admission 1.13, 1.01 to 1.27, cardiovascular disease 1.20, 1.00 to 1.45, and psychiatric disorders 2.34, 1.41 to 3.91). High stress was not associated with increased admission for coronary heart disease (1.00, 0.76-1.32) and showed an inverse relation with all cause mortality, mortality from cardiovascular disease, and mortality from coronary heart disease, that was attenuated by adjustment for occupational class (fully adjusted hazard ratio for all cause mortality 0.94, 0.81 to 1.11, cardiovascular mortality 0.91, 0.78 to 1.06, and mortality from coronary heart disease 0.98, 0.75 to 1.27). Conclusions: The relation between higher stress, angina, and some categories of hospital admissions probably resulted from the tendency of participants reporting higher stress to also report more symptoms. The lack of a corresponding relation with objective indices of heart disease suggests that these symptoms did not reflect physical disease. The data suggest that associations between psychosocial measures and disease outcomes reported from some other studies may be spurious

Limitations of adjustment for reporting tendency in observational studies of stress and self reported coronary heart disease

Recently, observational evidence has been suggested to show a causal association between various "psychosocial" exposures, including psychological stress, and heart disease. Much of this evidence derives from studies in which a self reported psychosocial exposure is related to an outcome dependent on the subjective experience of coronary heart disease (CHD) symptoms. Such outcomes may be measured using standard symptom questionnaires (like the Rose angina schedule). Alternatively they may use diagnoses of disease from medical records, which depend on an individual perceiving symptoms and reporting them to a health worker. In these situations, reporting bias may generate spurious exposure-outcome associations. For example if people who perceive and report their life as most stressful also over-report symptoms of cardiovascular disease then an artefactual association between stress and heart disease will result

Cause-specific hospital admission and mortality among working men: association with socioeconomic circumstances in childhood and adult life, and the mediating role of daily stress

BACKGROUND: The aim of this study was to investigate the association of childhood and adulthood social class with the occurrence of specific diseases, including those not associated with a high mortality rate, and to investigate daily stress as the mechanism for that part of any association which cannot be accounted for by established risk factors. METHODS: This was a prospective cohort study with 25 years of follow-up for cause-specific morbidity and mortality. A total of 5577 Scottish men were recruited from 27 workplaces in the West of Scotland. Childhood social class was determined from the occupation held by the individual's father, and adulthood social class from the individual's occupation at enrolment. Daily stress was measured at enrolment using the Reeder Stress Inventory. RESULTS: Health differentials were found for cardiovascular diseases, lung cancer, peptic ulcer, asthma, accidents and violence, alcohol-related diseases, and perhaps psychiatric illness. Adulthood circumstances were associated with the incidence of most diseases in adulthood, the exception being stroke, which was strongly associated with less privileged circumstances in childhood. Both childhood and adulthood circumstances contributed to the incidence of coronary heart disease. Daily stress did not underlie any of these associations once the influence of established risk factors had been taken into account. CONCLUSIONS: Socioeconomic circumstances in childhood and adulthood both contribute to health differentials in adulthood, the relative contributions depending upon the particular disease. Where known risk factors explained only part of the excess of a disease among individuals raised or living in less-privileged circumstances, there was no evidence to suggest that daily stress was the reason for the unexplained excess

Solar Coronal Structures and Stray Light in TRACE

Using the 2004 Venus transit of the Sun to constrain a semi-empirical point-spread function for the TRACE EUV solar telescope, we have measured the effect of stray light in that telescope. We find that 43% of 171A EUV light that enters TRACE is scattered, either through diffraction off the entrance filter grid or through other nonspecular effects. We carry this result forward, via known-PSF deconvolution of TRACE images, to identify its effect on analysis of TRACE data. Known-PSF deconvolution by this derived PSF greatly reduces the effect of visible haze in the TRACE 171A images, enhances bright features, and reveals that the smooth background component of the corona is considerably less bright (and hence much more rarefied) than commonly supposed. Deconvolution reveals that some prior conlclusions about the Sun appear to have been based on stray light in the images. In particular, the diffuse background "quiet corona" becomes consistent with hydrostatic support of the coronal plasma; feature contrast is greatly increased, possibly affecting derived parameters such as the form of the coronal heating function; and essentially all existing differential emission measure studies of small features appear to be affected by contamination from nearby features. We speculate on further implications of stray light for interpretation of EUV images from TRACE and similar instruments, and advocate deconvolution as a standard tool for image analysis with future instruments such as SDO/AIA.Comment: Accepted by APJ; v2 reformatted to single-column format for online readabilit

Tsunami Evacuation Planning as a tool for Tsunami Risk Reduction: A case study in Palu Bay, Central Sulawesi

Situated in one of the most complicated tectonic zones of the world, Palu is classified as one of the most susceptible places to earthquake and tsunami in Indonesia. This study aim to develop near-field tsunami evacuation simulation, as the primary strategy to reduce casualties in disaster risk reduction, based on daytime and night-time population scenarios in a tsunami-prone area in Palu Bay, Central Sulawesi. Least Cost Distance, a geospatial evacuation analysis approach in ArcGIS, is applied involving three main variables, namely population exposure, the arrival time of tsunami and walking speed of evacuees. These variables were analysed to calculate distribution of populations in daytime and night-time scenario; to identify and calculate the capacity of potential existing evacuation shelter buildings (ESB); and to analyse suitable locations, and to calculate the number and capacity of additional ESBs based on the most effective evacuation route. This study found that of the population in the study area, about 62.60 % cannot be sheltered in the seven existing ESB in the daytime as well as 63.98% of total population in the night-time scenario. Meanwhile,only 60.13% and 61.83% of the population in the service area of existing ESBs, can be evacuated in daytime and night-time scenarios, respectively. Therefore, eleven and twelve additional ESBs are proposed to be established for daytime and night-time scenarios, respectively, to accommodate people who currently cannot be sheltered

Thermal Conductivity of Nickel and Uranium

The thermal conductivity of a metal can be measured at any temperature by a method in which the conductivity of the metal under investigation is compared with the known conductivity of some metal chosen as a standard (1). The rate of heat flow, Q, in a cylindrical specimen of unknown conductivity, is given by the equation Q = - K1AG1, where Ki is the unknown thermal conductivity, A is the cross-sectional area, and G1 = (ΔT/Ax)1 is the temperature gradient. If a cylindrical bar of equal cross-sectional area and known thermal conductivity, K2, is placed in series with the specimen so that the rate of heat flow is the same in both bars, we have Q = -K2AG2, where G2 = (ΔT/ΔX)2 is the temperature gradient in the standard sample. From these two expressions for Q, the unknown thermal conductivity, K1 = (G2/G1)K2, can be found if the temperature gradients in the two rods are measured. In principle, the comparison method is simple but, in practice, complications may arise at high temperatures in providing good thermal contacts, in preventing radial heat losses, and in making reliable temperature measurements. The method has not, therefore, been characterized by high precision at elevated temperatures. The purpose of this investigation was (a) to develop improvements in the apparatus for measuring thermal conductivities of metals at high temperatures by the comparison method, and (b) to determine the thermal conductivities of nickel and uranium in the temperature range 100° C. to 650° C. by the comparison method

Deceleration and Dispersion of Large-scale Coronal Bright Fronts

One of the most dramatic manifestations of solar activity are large-scale coronal bright fronts (CBFs) observed in extreme ultraviolet (EUV) images of the solar atmosphere. To date, the energetics and kinematics of CBFs remain poorly understood, due to the low image cadence and sensitivity of previous EUV imagers and the limited methods used to extract the features. In this paper, the trajectory and morphology of CBFs was determined in order to investigate the varying properties of a sample of CBFs, including their kinematics and pulse shape, dispersion, and dissipation. We have developed a semi-automatic intensity profiling technique to extract the morphology and accurate positions of CBFs in 2.5-10 min cadence images from STEREO/EUVI. The technique was applied to sequences of 171A and 195A images from STEREO/EUVI in order to measure the wave properties of four separate CBF events. Following launch at velocities of ~240-450kms^{-1} each of the four events studied showed significant negative acceleration ranging from ~ -290 to -60ms^{-2}. The CBF spatial and temporal widths were found to increase from ~50 Mm to ~200 Mm and ~100 s to ~1500 s respectively, suggesting that they are dispersive in nature. The variation in position-angle averaged pulse-integrated intensity with propagation shows no clear trend across the four events studied. These results are most consistent with CBFs being dispersive magnetoacoustic waves.Comment: 15 pages, 18 figure

Particle abundance in a thermal plasma: quantum kinetics vs. Boltzmann equation

We study the abundance of a particle species in a thermalized plasma by introducing a quantum kinetic description based on the non-equilibrium effective action. A stochastic interpretation of quantum kinetics in terms of a Langevin equation emerges naturally. We consider a particle species that is stable in the vacuum and interacts with \emph{heavier} particles that constitute a thermal bath in equilibrium and define of a fully renormalized single particle distribution function. The distribution function thermalizes on a time scale determined by the \emph{quasiparticle} relaxation rate. The equilibrium distribution function depends on the full spectral density and features off-shell contributions to the particle abundance. A model of a bosonic field $\Phi$ in interaction with two \emph{heavier} bosonic fields is studied. We find substantial departures from the Bose-Einstein result both in the high temperature and the low temperature but high momentum region. In the latter the abundance is exponentially suppressed but larger than the Bose-Einstein result. We obtain the Boltzmann equation in renormalized perturbation theory and highlight the origin of the differences. We argue that the corrections to the abundance of cold dark matter candidates are observationally negligible and that recombination erases any possible spectral distortions of the CMB. However we expect that the enhancement at high temperature may be important for baryogenesis.Comment: 39 pages, 11 figures. Clarifying remarks. To appear in Physical Review