Co-morbidities associated with Non Alcoholic Fatty Liver Disease in Tertiary Care Hospital of central India

Background: Non-alcoholic fatty liver disease (NAFLD) is emerging as an important cause of liver disease. Over the past decades, it has become increasingly clear that nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are now the number one cause of liver disease all over the world. Objectives: To study co-morbidities associated with Non Alcoholic Fatty Liver Disease. Methods: 108 Persons with Non Alcoholic Fatty Liver Disease diagnosed by USG irrespective of age admitted in hospital from September. 2014 to August 2015 were enrolled in this study after applying inclusion and exclusion criterion. The comparison of qualitative data was done using chi-square test using SPSS 16 Version. Results: 89.13% of female patients had raised SGOT levels when compared to males (58.06%) and this difference was found to be statistically significant. The proportion of elevated levels of SGPT was more among female (89.13%) study subjects when compared to male subjects (59.68%) and this difference was statistically significant. The proportion of female study subjects with metabolic syndrome (82.61%) was more when compared with male study subjects (75.81%) and this difference was not found to be statistically significant. Conclusion: As noticed by this study, NAFLD were predominantly asymptomatic. Screening to be done in high risk patients so that progression to cirrhosis and Hepatocellular carcinoma can be prevented