Hubungan Karakteristik Rumah dengan Kejadian Penyakit Tuberkulosis Paru di Puskesmas Simpang Kiri Kota Subulussalam Tahun 2012

Corelation of house characteristic with the prevalence of pulmonary tuberculosis at public health centre Simpang Kiri Subulussalam city 2012. Pulmonary Tuberculosis is a communicable disease which is caused by mycobacterium tuberculosis that lives in high humidity place, and house in one of media that gives high influence to the mycobacterium tuberculosis's growth and its transmitting if the condition do not complete the term of health. Tuberkulosis bacteria can lives for weeks depend on the present of ultraviolet, the condition of ventilation, humidity, temperature and over crowding. The aim of this research was for determining the relation between the characteristics of house with the prevalence of pulmonary tuberculosis.The design of this research was Case Control. Total samples of this research was 50 respondents which is consist of 25 respondents for case that as the sufferer of pulmonary tuberculosis which recorded on the medical record of public health centre Simpang Kiri Kota Subulussalam city, and 25 respondents for Control, that was the people who lives around the sufferer of pulmonary tuberculosis by matching the characteristics age and gender with case. The data was analiyzed by Chi Square with degree of confidence was 5 %. Accourding to the result of this research, there was a significant differend between the characteristics of citizen's house who suffer from pulmonary tuberculosis. With the citizens who didn't suffer from it. The data shows, that Odds Ratio Of the density of living is 13,5, ventilation is 30,5, type of floor is 22,1, lighting is 9,3, temperature is 27,5 and humidity is 84,4 it is estimated that the characteristic of citizen's house who didn't suffer from it this condition indicate that there is relation between the characteristic of house with the prevalence of pulmonary tuberculosis in public health centre Simpang Kiri area Subulussalam city in 2012

Difference in Computer-Attributed Vision Problem between Laptop and Desktop Users

Background: Occupational health is a key component of an industry. This is because a strong safety culture boosts productivity, employee morale, and employee retention. A strong ergonomics integration prevents injuries and increases productivity. They make the workplace safer and reduce costs. Ergonomics also must be incorporated and seen as a value. It needs to be built into a corporate culture and be integrated into everything any company does on a daily basis, including that in the administrative office where workers frequently use computers. This study aimed to analyze difference in computer-attributed vision problem between laptop and desktop computer users. Subjects and Method: This was a cross sectional study conducted in North Sumatera. A sample of 60 subjects consisting of 30 laptop users and 30 desktop users were selected for this study by purposive sampling. The dependent variable was vision problem. The independent variable was computer type. The data were collected by questionnaire and tested by Mann Whitney test. Results: Among the laptop users, 80% experienced neck pain, 77% eye strain, and 70% low back pain. Among the desktop-computer user, 50% experienced neck pain, 77% eye fatigue, and 33% eye irritation. Mean score of complaints in the laptop user group was 2.54 units higher than the desktop-computer user group (p= 0.001). Conclusion: Laptop users experienced more complaints than desktop-computer users. Workers using computers are suggested to have regular break to allow body organs to take a rest. Workers are also suggested to work at an ample distance between eyes and computer screen. Employers are responsible for providing a safe and healthful workplace for their workers. Keywords: vision problem, computer-attributed, laptop, desktop computer, ergonom

Difference in Computer Vision Syndrome Between Laptop and Desktop Computer Users

Background: Occupational health is a key component of an industry. This is because a strong safety culture boosts productivity, employee morale, and employee retention. A strong ergonomics integration prevents injuries and increases productivity. They make the workplace safer and reduce costs. Ergonomics also must be incorporated and seen as a value. It needs to be built into a corporate culture and be integrated into everything any company does on a daily basis, including that in the administrative office where workers frequently use computers. This study aimed to analyze difference in computer-attributed vision problem between laptop and desktop computer users.Subjects and Method: This was a cross sectional study conducted in North Sumatera. A sample of 60 subjects consisting of 30 laptop users and 30 desktop users were selected for this study by purposive sampling. The dependent variable was vision problem. The independent variable was computer type. The data were collected by questionnaire and tested by Mann Whitney test.Results: Among the laptop users, 80% experienced neck pain, 77% eye strain, and 70% low back pain. Among the desktop-computer user, 50% experienced neck pain, 77% eye fatigue, and 33% eye irritation. Mean score of complaints in the laptop user group was 2.54 units higher than the desktop-computer user group (p= 0.001).Conclusion: Laptop users experienced more complaints than desktop-computer users. Workers using computers are suggested to have regular break to allow body organs to take a rest. Workers are also suggested to work at an ample distance between eyes and computer screen. Employers are responsible for providing a safe and healthful workplace for their workers.Keywords: vision problem, computer-attributed, laptop, desktop computer, agronomyCorrespondence:Putri Anggrainy. Department of Occupational Health and Safety, Faculty Public Health, Universitas North Sumatera. Email: [email protected]. Mobile: +6285763191981.Indonesian Journal of Medicine (2018), 3(2): 65-70https://doi.org/10.26911/theijmed.2018.03.02.0

PERENCANAAN SALURAN SEKUNDER DAERAH IRIGASI AIR GAUNG KECIL KABUPATEN LAHAT PROVINSI SUMATERA SELATAN

The final report contains the planning of irrigation in the village High Gutters and Muara Muara Payang Gelumpai Lahat. This report discusses the planning and calculation of the dimensions of the secondary channels of the Secondary Channels Small Echoes Segment 1 (SSGKR1) to Secondary Channel Small Echoes Segment 11 (SSGKR11) with a total length of 3593.76 m channel. It is also in this planning there are 15 tertiary canals. Where the purpose of the construction project of irrigation channels Small Echoes Water area is to support the national food supply, so it is necessary to be the availability of water in the area even though the land is located far from sources of water. The data plan for this final report include rainfall data, map, and others. The method used is the method mean Algebra and methods of Penman and others. From the calculation results obtained for SSGKR1 secondary channel dimensions, with A = 308Ha, Q = 0540 m3 / s, L = 144.85 m. SSGKR2, with A = 303Ha, Q = 0531 m3 / s, L = 401 m. SSGKR3, with A = 267,3Ha, Q = 0469 m3 / s, L = 181.16 m. SSGKR4, with A = 258.5Ha, Q = 0453 m3 / s, L = 194.93 m. SSGKR5, with A = 206,9Ha, Q = 0.363 m3 / s, L = 375.13 m. SSGKR6, with A = 196,4Ha, Q = 0334 m3 / s, L = 531.68 m. SSGKR7, with A = 169,7Ha, Q = 0298 m3 / s, L = 513.38 m. SSGKR8, with A = 148,1Ha, Q = 0.260 m3 / s, L = 281.31 m. SSGKR9, with A = 104,8Ha, Q = 0184 m3 / s, L = 170.04 m. SSGKR10, with A = 95,80Ha, Q = 0168 m3 / s, L = 497.59 m. SSGKR11, with A = 87,30Ha, Q = 0153 m3 / s, L = 302.69 m. In this plan requires funding budget of Rp 22.277.643.277,64. Keywords: Irrigation, Water Small Echoes, Secondary Channel

Milk and milk-derived peptides combat against hypertension and vascular dysfunction : a review

Epidemiological studies have revealed that consumption of milk and fermented dairy products is inversely associated with elevated blood pressure and with many of the risk factors of the metabolic syndrome. Previously, calcium was thought to be behind this phenomenon, but during the last 20 years, convincing evidence emerging from experimental, epidemiological and intervention studies has highlighted the important role of the small peptides formed during fermentation processes. This review provides an overview of the potential blood pressure lowering components present in dairy products with a special focus on casein-derived tripeptides.Peer reviewe

Endogenous U2.U5.U6 snRNA complexes in S. pombe are intron lariat spliceosomes

Excision of introns from pre-mRNAs is mediated by the spliceosome, a multi-megadalton complex consisting of U1, U2, U4/U6, and U5 snRNPs plus scores of associated proteins. Spliceosome assembly and disassembly are highly dynamic processes involving multiple stable intermediates. In this study, we utilized a split TAP-tag approach for large-scale purification of an abundant endogenous U2.U5.U6 complex from Schizosaccharomyces pombe. RNAseq revealed this complex to largely contain excised introns, indicating that it is primarily ILS (intron lariat spliceosome) complexes. These endogenous ILS complexes are remarkably resistant to both high-salt and nuclease digestion. Mass spectrometry analysis identified 68, 45, and 43 proteins in low-salt-, high-salt-, and micrococcal nuclease-treated preps, respectively. The protein content of a S. pombe ILS complex strongly resembles that previously reported for human spliced product (P) and Saccharomyces cerevisiae ILS complexes assembled on single pre-mRNAs in vitro. However, the ATP-dependent RNA helicase Brr2 was either substoichiometric in low-salt preps or completely absent from high-salt and MNase preps. Because Brr2 facilitates spliceosome disassembly, its relative absence may explain why the ILS complex accumulates logarithmically growing cultures and the inability of S. pombe extracts to support in vitro splicing

Effect of sex and underlying disease on the genetic association of QT interval and sudden cardiac death

Background Sudden cardiac death (SCD) accounts for ≈300 000 deaths annually in the United States. Men have a higher risk of SCD and are more likely to have underlying coronary artery disease, while women are more likely to have arrhythmic events in the setting of inherited or acquired QT prolongation. Moreover, there is evidence of sex differences in the genetics of QT interval duration. Using sex‐ and coronary artery disease–stratified analyses, we assess differences in genetic association between longer QT interval and SCD risk. Methods and Results We examined 2282 SCD subjects and 3561 Finnish controls. The SCD subjects were stratified by underlying disease (ischemic versus nonischemic) and by sex. We used logistic regression to test for association between the top QT interval–associated single‐nucleotide polymorphism, rs12143842 (in the NOS1AP locus), and SCD risk. We also performed Mendelian randomization to test for causal association of QT interval in the various subgroups. No statistically significant differences were observed between the sexes for associations with rs12143842, despite the odds ratio being higher in females across all subgroup analyses. Consistent with our hypothesis, female non‐ischemics had the highest odds ratio point estimate for association between rs12143842 and SCD risk and male ischemics the lowest odds ratio point estimate (P=0.036 for difference). Similar trends were observed for the Mendelian randomization analysis. Conclusions While individual subgroup comparisons did not achieve traditional criteria for statistical significance, this study is consistent with the hypothesis that the causal association of longer QT interval on SCD risk is stronger in women and nonischemic individuals

Diagnostic accuracy of WHO screening criteria to guide lateral-flow lipoarabinomannan testing among HIV-positive inpatients: A systematic review and individual participant data meta-analysis

BACKGROUND: WHO recommends urine lateral-flow lipoarabinomannan (LF-LAM) testing with AlereLAM in HIV-positive inpatients only if screening criteria are met. We assessed the performance of WHO screening criteria and alternative screening tests/strategies to guide LF-LAM testing and compared diagnostic accuracy of the WHO AlereLAM algorithm (WHO screening criteria → AlereLAM) with AlereLAM and FujiLAM (a novel LF-LAM test). METHODS: We searched MEDLINE, Embase, and Cochrane Library from Jan 1, 2011 to March 1, 2020 for studies among adult/adolescent HIV-positive inpatients regardless of tuberculosis signs and symptoms. The reference standards were 1) AlereLAM or FujiLAM for screening tests/strategies and 2) culture or Xpert for AlereLAM/FujiLAM. We determined proportion of inpatients eligible for AlereLAM using WHO screening criteria; assessed accuracy of WHO criteria and alternative screening tests/strategies to guide LF-LAM testing; compared accuracy of WHO AlereLAM algorithm with AlereLAM/FujiLAM in all; and determined diagnostic yield of AlereLAM, FujiLAM, and Xpert MTB/RIF (Xpert). We estimated pooled proportions with a random-effects model, assessed diagnostic accuracy using random-effects bivariate models, and assessed diagnostic yield descriptively. FINDINGS: We obtained data from all 5 identified studies (n=3,504). The pooled proportion of inpatients eligible for AlereLAM using WHO criteria was 93% (95%CI 91, 95). Among screening tests/strategies to guide LF-LAM testing, WHO criteria, C-reactive protein (≥5 mg/L), and CD4 count (<200 cells/μL) had high sensitivities but low specificities; cough (≥2 weeks), haemoglobin (<8 g/dL), body mass index (<18.5 kg/m2), lymphadenopathy, and WHO-defined danger signs had higher specificities but suboptimal sensitivities. AlereLAM in all had the same sensitivity (62%) and specificity (88%) as WHO AlereLAM algorithm. Sensitivity of FujiLAM and AlereLAM was 69% and 48%, while specificity was 48% and 96%, respectively. Diagnostic yield of sputum Xpert was 29-41%, AlereLAM was 39-76%, and urine Xpert was 35-62%. In one study, FujiLAM diagnosed 80% of tuberculosis cases (vs 39% for AlereLAM), and sputum Xpert combined with AlereLAM, urine Xpert, or FujiLAM diagnosed 69%, 81%, and 92% of all cases, respectively. INTERPRETATION: WHO criteria and alternative screening tests/strategies have limited utility in guiding LF-LAM testing, suggesting that AlereLAM testing in all HIV-positive medical inpatients be implemented. Routine FujiLAM may improve tuberculosis diagnosis. FUNDING: None

LAPORAN PELAKSANAAN KULIAH KERJA NYATA REGULER UNIVERSITAS AHMAD DAHLAN PERIODE LXI TAHUN AKADEMIK 2016/2017, DESA GONDORIYO, KECAMATAN JAMBU, KABUPATEN SEMARANG.

KKN REGULER UAD PERIODE LXI GONDORIYO DIVISI II.B.