High-load injuries in the adolescent athlete's hip; clinical and experimental studies and outcome measures

The diagnosis and treatment of hip and groin symptoms has often been a problem area in orthopaedics and sports medicine. Hip and groin pain and injuries are common among athletes and in the increasingly active population. In recent years, femoroacetabular impingement (FAI) has emerged as one of the most common causes of hip and groin disability in this group and it is a known risk factor in the development of osteoarthritis (OA) of the hip. Technical advancement and improved instruments have made surgical hip arthroscopy the mainstay treatment option in patients with debilitating FAI and the indications for hip arthroscopy are increasing. The aetiology of FAI is not known. Several theories have been proposed. One of them is that a growth disturbance in the proximal femur, caused by heavy loads during skeletal maturation, is a factor in FAI development. FAI has been seen to be more common in athletes in certain sports, leading to pain, reduced range of motion (ROM) and performance. Despite the increase in the number of hip arthroscopies that are performed, outcome measurements for the young and middle-aged, active patient with hip and groin pain have been lacking. Other instruments developed for older patients with osteoarthritis of the hip have been used, but their psychometric properties in this patient group are deficient. In a clinical study, the morphological characteristics and ROM of the hips were compared in a group of athletes and a group of non-athletes. No difference in hip morphology was found between the groups, but the athletes had significantly lower ROM and osteoarthritis was more common among the athletes. The strength of the porcine proximal femoral physis was investigated in two biomechanical studies. The physeal plate was found to be the weakest point in the proximal femur. Injuries were seen after repeated physiological loading in and around the physeal plate both on MRI and histologically. Two patient-reported outcome measurements (HRPROMs) developed for these patient groups were found, the iHOT12 and HAGOS. Using standardised methods, the HR-PROMs were translated and adapted to Swedish and the Swedish versions were tested in a clinical study to measure their psychometric properties. Morphological changes of FAI increase the risk of OA development. Injuries created in and around the physeal plate in the proximal femur during physiological loads can lead to morphological changes and FAI. The Swedish versions of the iHOT12 and HAGOS have good psychometric properties and can be used clinically and for research

Gastrointestinal Stromal Tumour (GIST). Case report

Neðst á síðunni er að nálgast greinina í heild sinni með því að smella á hlekkinn View/OpenIn 1987 a 73 year old man was diagnosed with a malignant sarcoma of the anus. It was originally regarded as a leiomyosarcoma. Fourteen years later the original diagnoses of the specimen was reviewed and the diagnosis was changed to GIST (gastrointestinal stromal tumour). This diagnosis was confirmed with appropriate immunohistochemical staining on the tumour tissue. This is the first case of GIST in the anus diagnosed in Iceland.Í þessu sjúkratilfelli er um að ræða sjötíu og þriggja ára karlmann sem greindist með illkynja sarkmein í daus (anus) og talið var af sléttvöðvatoga (leiomyosarcoma). Við endurskoðun á sýnum sjúklings í apríl árið 2004 vaknaði sá grunur að um væri að ræða strómaæxli í meltingarvegi (GastroIntestinal Stromal Tumour, GIST). Þessi greining var í framhaldi staðfest með viðeigandi mótefnalitunum á æxlisvefnum. Þetta er fyrsta tilfelli GIST í daus hér á landi