A cobalt arylphosphonate MOF – superior stability, sorption and magnetism

We report a novel metal-organic framework (MOF) based on a cobalt arylphosphonate, namely, [Co2(H4-MTPPA)]·3NMP·H2O (1·3NMP·H2O), which was prepared solvothermically from the tetrahedral linker tetraphenylmethane tetrakis-4-phosphonic acid (H8-MTPPA) and CoSO4·7H2O in N-methyl-2-pyrrolidone (NMP). Compound 1 has the highest porosity (BET surface area of 1034 m2 g−1) ever reported for a MOF based on an aryl phosphonic acid linker. The indigo blue crystals of 1·3NMP·H2O are composed of edge-shared eight-membered Co2P2O4 rings, and are thermally very stable up to 500 °C.TU Berlin, Open-Access-Mittel - 201

The Case of an Elderly Male Patient with Unknown Primary Mucinous Adenocarcinoma within Presacral Teratoma (Teratoma with Malignant Transformation)

Teratomas are rarely seen in adults, and presacral region is an area where they rarely settle in. Similarly, only about 1% of teratomas show malignant transformation. Malignant transformation is often associated with the area where teratoma settles in. Malignant transformation of mediastinal teratomas is more frequent than the ones located in retroperitoneal area and gonad. They most commonly show rhabdomyosarcoma, primitive neuroectodermal tumor, enteric adenocarcinoma, and leukemia transformation. In teratomas showing malignant transformation, the clinical course is aggressive; and survival of patients with metastatic disease is very low. The primary treatment of teratomas with malignant transformations is surgical. Effect of radiotherapy and chemotherapy is not clear in patients, to whom surgical operation cannot be applied, or those who are with residual tumor, even if surgical operation can be applied to them, or those who are at metastatic stage. In this paper, we presented a 76-year-old male patient due to the histologic diagnosis of mucinous adenocarcinoma within teratoma, in whom approximately 7 cm presacral mass was found during the radiographic examination made by the reason of low back pain and pelvic pain

Okul öncesi çocuklarda erken çocukluk çağı çürüklerine etki eden faktörlerin değerlendirilmesi: Kesitsel Çalışma

Giriş ve Amaç: Bu çalışmanın amacı, erken çocukluk çağı çürüklerinin (EÇÇ) şiddetinin ve sıklığının değerlendirilerek sosyoekonomik şartlar, eğitim ve yaşam alışkanlıkları parametreleri ile ilişkisinin belirlenmesidir.Yöntem ve Gereçler: Bu araştırma İzmir Eğitim Diş Hastanesi Çocuk Diş Kliniğine muayene için başvuran yaşları 3-5 arasında olan 251 çocuk üzerinde yürütüldü. Hastaların ağız içi muayeneleri yapılarak çürük durumu Dünya Sağlık Örgütü kriterlerine göre tespit edildi. Anne-baba ve çocuklara ait demografik bilgiler, çocukların beslenme ve ağız hijyeni alışkanlıklarına ait veriler anket formlarına kaydedildi. İstatistiksel değerlendirme Ki Kare, Kruskal Wallis ve Mann-Whitney U testleri kullanılarak yapıldı. İstatistiksel anlamlılık p<0.05 olarak kabul edildi.Bulgular: EÇÇ sıklığı %90 (226/251), Şiddetli-EÇÇ (Ş-EÇÇ) sıklığı %61 (153/251), dmft ve dmfs indeksi değerleri ise sırasıyla 5,65±3,83 ve 9,37±7,21 olarak bulundu. EÇÇ ve Ş-EÇÇ varlığı; cinsiyet (p=0,460), ailenin eğitim seviyesi (p=0,200) ve gelir seviyesi (p=0,761) ile değerlendirildiğinde istatistiksel olarak anlamlı değilken, 1-2 yaşına kadar geceleri beslenen çocuklarda (p<0,001), günde 3 kereden fazla şekerli gıda tüketimi yapan çocuklarda (p<0,001), dişlerini fırçalamayan çocuklarda (p<0,001) ve ebeveyn yardımı almadan dişlerini fırçalayan çocuklarda (p<0,001) istatistiksel olarak anlamlı düzeyde saptandı. Tartışma ve Sonuç: Ailelerin ağız sağlığı/hijyen konusunda eğitilmesi ve çocuklarına yardımcı olmaları için motive edilmeleri önerilmektedir

Is there a relationship between maternal periodontitis and pre-term birth? A prospective hospital-based case-control study

Objective. The aim of this study is to verify the existence of an association between maternal periodontal disease and pre-term delivery in an unselected population of post-partum Turkish women. Materials and methods. This case-control study was conducted on 100 women who gave birth in either a special or a government maternity hospital. The case group consisted of 50 mothers who had delivered an infant before 37 weeks' gestation and weighed under 2500 g. The control group included 50 mothers who had given birth to an infant with a birth weight of more than 2500 g and a gestational age of >= 37 weeks. Data of mothers and infants were collected using medical registers and questionnaires. Clinical periodontal examinations were carried out in six sites on every tooth in the mother's mouth. A participant who presented at least four teeth with one or more sites with a PPD >= 4 mm and CAL >= 3 mm at the same site was considered to have periodontal disease. Statistical methods included parametric and non-parametric tests and multiple logistic regression analysis. Results. There were no statistically significant differences between the cases and controls with regard to periodontal disease and pre-term delivery (OR = 1.48; 95% CI = 0.54-4.06). Conclusion. The findings indicated that maternal periodontitis was not a possible risk factor for pre-term delivery. Further studies with additional clinical trials are needed to explore the possible relationship between periodontal disease and pre-term birth

Intracytoplasmic sperm injection in male renal transplant recipients

Objective: In this study, we reviewed the reproductive outcomes following ICSI in 5 couples where the male partners had undergone renal transplantations. Chronic renal failure and dialysis may adversely affect male reproductive function resulting in severely depressed semen parameters or even azoospermia, which maybe further adversely affected by the immunosuppression taken from after transplantation. Study design: Case report. Setting: A private fertility clinic. Patients: The study included five infertile couples where the male partners were the recipients of renal transplants, 3–15 years prior to having ICSI treatment. All couples suffered from male factor infertility, with diagnoses of; azoospermia, asthenoteratozoospermia, oligoasthenoteratozoopsermia. Results: In the 5 case reports 5 ICSI and 3 FET treatment procedures were completed. In all but one of the cases grade 1 quality embryos were obtained and transferred. From the 8 embryo transfers performed 4 pregnancies were obtained, one miscarried at 8 weeks and 3 resulted in live births. Conclusions: In this study, we showed that pregnancy and normal live birth were possible following ICSI treatment for male factor infertility, where male partners had had renal transplants and were under immunosuppressive therapy

Risk of ovarian torsion is reduced in GnRH agonist triggered freeze-all cycles: a retrospective cohort study

Ovarian torsion (OT) in IVF is rare, however, the consequences are significant, which include ovariotomy. In the present study, it was aimed for the first time to compare the incidence of OT between hCG triggered cycles with ICSI and fresh transfer and GnRH-agonist triggered cycles with the ICSI-freeze-all and frozen embryo transfer (FET). In total, 15,577 ICSI cycles performed between 2001 and 2016 were categorised into two groups (Group 1, n: 9978): cycles with controlled ovarian stimulation (COS) and hCG-triggered (Group 2, n: 5599) and COS, with GnRH-agonist only triggered and freeze-all. Thirteen patients (0.13%) were diagnosed with OT and corrected by laparoscopy (12) and laparotomy (1) in Group 1. One patient (0.018%) was diagnosed with OT and corrected by laparotomy in Group 2 (Group 1 vs. Group 2, p = .049). The incidence of severe ovarian hyperstimulation syndrome (OHSS) was 2.4% in Group 1 and 0.05% in Group 2 (p < .001). The use of freeze-all with GnRH agonist trigger in ART significantly reduced the incidence of OT and concomitantly OHSS, with no effect on the reproductive outcome.Impact Statement What is already known on this subject? Adnexal ovarian torsion (OT) is a well-known gynaecological event that constitutes a surgical emergency. Assisted reproduction technologies (ART) may result in ovarian conditions that predispose patients to ovarian hyperstimulation syndrome (OHSS) and torsion. What the results of this study add? The combined use of GnRH agonist trigger for final oocyte maturation after OS with freeze-all and frozen embryo transfer (FET) significantly reduces the incidence of OT, as well as OHSS. What the implications are of these findings for clinical practice and/or further research? The treatment strategy of GnRH agonist trigger with freeze-all significantly reduces the risks of adverse complications

Determination of groundwater threshold values: A methodological approach

This article is concerned with the establishment of natural background levels and threshold values for naturally-occurring parameters in groundwaters in the absence of relevant and accurate long-term spatial data. A new approach was developed and exemplified, adopting the groundwaters of the Gediz River Basin, Turkey, as a case study. The available groundwater monitoring data was from a one-year seasonal water quality monitoring campaign. The approach used combines pre-selection, selection and statistical evaluation of the selected data to eliminate outliers to determine natural background levels. The application of three different statistical tools, namely, probability plot, 2-sigma iteration, and distribution function methods, resulted in different natural background level estimates. The 2-sigma iteration method provided the most conservative values for almost all the parameters. The use of this three-step approach, which adopts different statistical methods, appeared to solve the limited data availability challenges specific to groundwater contamination and improve natural background level assessment and threshold value setting. Lessons learned from this study can help policymakers to promote similar initiatives in other countries where groundwater quality data is limited