Hypertension in the elderly

WOS: 000418482900009PubMed ID: 28976377Hypertension (HT) is a common problem in elderly persons (age >65 years), reaching a prevalence as high as 60 to 80%. Isolated systolic HT mostly occurs in older patients. Treatment of HT in all patients, independent of age, consists of lifestyle modifications and antihypertensive therapy. Randomized trials have provided clear evidence of benefit from treating HT in elderly patients, including those over the age of 80 years. Drug therapy should be started in elderly hypertensive patients if lifestyle changes are insufficient and in the absence of a hypertensive emergency or urgency, blood pressure reduction should always be gradual. A long-acting dihydropyridine or a thiazide diuretic is generally preferred because of increased blood pressure-lowering efficacy in this population. Goal blood pressure recommendation for most hypertensive elderly is to attain a systolic pressure below 140 mmHg

Changes in cardiovascular physiology in the elderly

WOS: 000418482900003PubMed ID: 28976371The ageing process is associated with important changes in the responses of the cardiovascular system. They are not limited to the arterial system, involved in the modulation of cardiac afterload and vascular resistance, but they also involve the low-resistance capacitance venous system and the heart. This review focuses on the effects of ageing on the cardiovascular morphological, functional, electrological system and vascular functions

Congenital left ventricular diverticulum as a cause of chest pain in an adult

WOS: 000249715600018PubMed ID: 1757293

Microbiological Profile, Echocardiographic Characteristics and Early Results of Infective Endocarditis: A Review of 194 Cases at a Tertiary Care Center in Turkey

29th Turkish Cardiology Congress of the Turkish-Society-of-Cardiology (TSC) with International Participation -- OCT 26-29, 2013 -- Antalya, TURKEYWOS: 000329858400182Turkish Soc Cardio

Epidemiological, Clinical Characteristics and Predisposing Factors of Infective Endocarditis: A review of 194 cases

29th Turkish Cardiology Congress of the Turkish-Society-of-Cardiology (TSC) with International Participation -- OCT 26-29, 2013 -- Antalya, TURKEYWOS: 000329858400181Turkish Soc Cardio

The effects of different hormone treatment on endothelial function in healthy postmenopausal women

WOS: 000323857900015PubMed ID: 23875965We aimed to compare the effects of different types of hormone treatment (HT) on endothelial function by means of brachial artery ultrasonographic examination in postmenopausal women. Sixty-two healthy postmenopausal women were included in this study. Subjects were assigned to one of the five groups receiving 6 months of treatment [estrogen (conjugated estrogen), estrogen (conjugated estrogen) plus progesterone (medroxyprogesterone acetate; MPA), raloxifene, tibolone or control]. Endothelial function was assessed by measurement of flowmediated dilatation (FMD) and nitrate-dependent dilatation in the brachial artery. At the end of 6 months, FMD values were found to be significantly increased in women with HT use than the control group (p= 0.001). In subgroups, FMD increased significantly in the estrogen [12 7 versus 25 8, p= 0.0011 and raloxifene groups [7+5 versus 11 3, p< 0.01] compared to tibolone and estrogen plus progesterone groups. In conclusion, endothelial function is impaired in postmenopausal women. Both estrogen and raloxifene regimens may improve endothelial functions in healthy postmenopausal women. The direct protective effects of these HT on the healthy endothelium may be more remarkable than the favorable effects on lipid profile