398 research outputs found
Plasmonic terahertz detection by a double-grating-gate field-effect transistor structure with an asymmetric unit cell
Plasmonic terahertz detection by a double-grating gate field-effect
transistor structure with an asymmetric unit cell is studied theoretically.
Detection responsivity exceeding 8 kV/W at room temperature in the photovoltaic
response mode is predicted for strong asymmetry of the structure unit cell.
This value of the responsivity is an order of magnitude greater than reported
previously for the other types of uncooled plasmonic terahertz detectors. Such
enormous responsivity can be obtained without using any supplementary antenna
elements because the double-grating gate acts as an aerial matched antenna that
effectively couples the incoming terahertz radiation to plasma oscillations in
the structure channel.Comment: Submitted to APL, 8 pages, 2 figure
Chromospheric Anemone Jets as Evidence of Ubiquitous Reconnection
The heating of the solar chromosphere and corona is a long-standing puzzle in
solar physics. Hinode observations show the ubiquitous presence of
chromospheric anemone jets outside sunspots in active regions. They are
typically 3 to 7 arc seconds = 2000 to 5000 kilometers long and 0.2 to 0.4 arc
second = 150 to 300 kilometers wide, and their velocity is 10 to 20 kilometers
per second. These small jets have an inverted Y-shape, similar to the shape of
x-ray anemone jets in the corona. These features imply that magnetic
reconnection similar to that in the corona is occurring at a much smaller
spatial scale throughout the chromosphere and suggest that the heating of the
solar chromosphere and corona may be related to small-scale ubiquitous
reconnection.Comment: 10 pages, 5 figure
Field Effect Transistors for Terahertz Detection: Physics and First Imaging Applications
Resonant frequencies of the two-dimensional plasma in FETs increase with the
reduction of the channel dimensions and can reach the THz range for sub-micron
gate lengths. Nonlinear properties of the electron plasma in the transistor
channel can be used for the detection and mixing of THz frequencies. At
cryogenic temperatures resonant and gate voltage tunable detection related to
plasma waves resonances, is observed. At room temperature, when plasma
oscillations are overdamped, the FET can operate as an efficient broadband THz
detector. We present the main theoretical and experimental results on THz
detection by FETs in the context of their possible application for THz imaging.Comment: 22 pages, 12 figures, review pape
Total gastrectomy with simultaneous pancreaticosplenectomy or splenectomy in patients with advanced gastric carcinoma
A splenectomy or distal pancreaticosplenectomy is often performed simultaneously with total gastrectomy in the treatment of gastric carcinoma to facilitate dissection of the lymph nodes around the splenic artery and splenic hilus. However, the negative impact of splenectomy and pancreaticosplenectomy has also been reported. A retrospective analysis was performed to evaluate the outcomes of distal pancreaticosplenectomy and total gastrectomy, splenectomy and total gastrectomy, and gastrectomy alone in the patients with advanced gastric carcinoma without distant metastasis. Prognostic factors were examined. No significant differences existed in 5-year survival in the patients who underwent gastrectomy with splenectomy, gastrectomy with distal pancreaticosplenectomy, or gastrectomy alone. Neither splenectomy, nor distal pancreaticosplenectomy were prognostic factors. However, distal pancreaticosplenectomy was an independent predictor of pancreatic fistula. In conclusion, the addition of distal pancreaticosplenectomy or splenectomy to total gastrectomy for gastric cancer increases the risk of severe complications, but does not improve survival. © 1999 Cancer Research Campaig
Overexpression of SMYD2 in gastric cancer
Background: SET and MYND domain-containing protein 2 (SMYD2) is a lysine methyltransferase for histone H3, p53 and Rb and inhibits their transactivation activities. In this study, we tested whether SMYD2 (1q42) acts as a cancer-promoting factor by being overexpressed in gastric cancer.
Methods: We analysed 7 gastric cancer cell lines and 147 primary tumor samples of gastric cancer, which were curatively resected in our hospital.
Results: SET and MYND domain-containing protein 2 was detected in these cell lines (five out of seven cell lines; 71.4%) and primary tumor samples (fifty-six out of one hundred and forty-seven cases; 38.1%). Knockdown of SMYD2 using specific small interfering RNA inhibited proliferation, migration and invasion of SMYD2-overexpressing cells in a TP53 mutation-independent manner. Overexpression of SMYD2 protein correlated with larger tumor size, more aggressive lymphatic invasion, deeper tumor invasion and higher rates of lymph node metastasis and recurrence. Patients with SMYD2-overexpressing tumours had a worse overall rate of survival than those with non-expressing tumours (P=0.0073, log-rank test) in an intensity and proportion score-dependent manner. Moreover, multivariate analysis demonstrated that SMYD2 was independently associated with worse outcome (P=0.0021, hazard ratio 4.25 (1.69–10.7)).
Conclusions: These findings suggest that SMYD2 has a crucial role in tumor cell proliferation by its overexpression and highlight its usefulness as a prognostic factor and potential therapeutic target in gastric cancer
The Horizontal Component of Photospheric Plasma Flows During the Emergence of Active Regions on the Sun
The dynamics of horizontal plasma flows during the first hours of the
emergence of active region magnetic flux in the solar photosphere have been
analyzed using SOHO/MDI data. Four active regions emerging near the solar limb
have been considered. It has been found that extended regions of Doppler
velocities with different signs are formed in the first hours of the magnetic
flux emergence in the horizontal velocity field. The flows observed are
directly connected with the emerging magnetic flux; they form at the beginning
of the emergence of active regions and are present for a few hours. The Doppler
velocities of flows observed increase gradually and reach their peak values
4-12 hours after the start of the magnetic flux emergence. The peak values of
the mean (inside the +/-500 m/s isolines) and maximum Doppler velocities are
800-970 m/s and 1410-1700 m/s, respectively. The Doppler velocities observed
substantially exceed the separation velocities of the photospheric magnetic
flux outer boundaries. The asymmetry was detected between velocity structures
of leading and following polarities. Doppler velocity structures located in a
region of leading magnetic polarity are more powerful and exist longer than
those in regions of following polarity. The Doppler velocity asymmetry between
the velocity structures of opposite sign reaches its peak values soon after the
emergence begins and then gradually drops within 7-12 hours. The peak values of
asymmetry for the mean and maximal Doppler velocities reach 240-460 m/s and
710-940 m/s, respectively. An interpretation of the observable flow of
photospheric plasma is given.Comment: 20 pages, 10 figures, 3 tables. The results of article were presented
at the ESPM-13 (12-16 September 2011, Rhodes, Greece, Abstract Book p. 102,
P.4.12,
http://astro.academyofathens.gr/espm13/documents/ESPM13_abstract_programme_book.pdf
- …