Ethnies et espace dans le Sud éthiopien. Regards croisés sur "A History of the Hadiyya in Southern Ethiopia (Braukämper, 2012) "

International audienc

The Awash River in Oromo Historical Narratives

In the continuity of the research on the Oromo initiated by the Western Christian missionaries since the nineteenth century, most of the academic studies published in the last decades have attempted to reveal the ‘authentic’ version of the Oromo culture and religion (Osmond 2014b). Beyond the holistic approach of classical anthropology privileged in these works, this exploratory study of the Oromo historical narratives on the Awash River aims at highlighting the value of questioning the plura..

Advanced maternal age causes adverse programming of mouse blastocysts leading to altered growth and impaired cardiometabolic health in post-natal life

Study question: does advanced maternal age (AMA) in mice affect cardiometabolic health during post-natal life in offspring derived from an assisted reproduction technology (ART) procedure?Summary answer: offspring derived from blastocysts collected from aged female mice displayed impaired body weight gain, blood pressure, glucose metabolism and organ allometry during post-natal life compared with offspring derived from blastocysts from young females; since all blastocysts were transferred to normalized young mothers, this effect is independent of maternal pregnancy conditions.What is known already: although studies in mice have shown that AMA can affect body weight and behaviour of offspring derived from natural reproduction, data on the effects of AMA on offspring cardiometabolic health during post-natal development are not available. Given the increasing use of ART to alleviate infertility in women of AMA, it is pivotal to develop ART–AMA models addressing the effects of maternal aging on offspring health.Study design, size, duration: blastocysts from old (34–39 weeks) or young (8–9 weeks) C57BL/6 females mated with young CBA males (13–15 weeks) were either subjected to differential cell staining (inner cell mass and trophectoderm) or underwent embryo transfer (ET) into young MF1 surrogates (8–9 weeks) to produce young (Young-ET, 9 litters) and old (Old-ET, 10 litters) embryo-derived offspring. Offspring health monitoring was carried out for 30 weeks.Participants/materials, setting, methods: all animals were fed with standard chow. Blood pressure was measured at post-natal Weeks 9, 15 and 21, and at post-natal Week 30 a glucose tolerance test (GTT) was performed. Two days after the GTT mice were killed for organ allometry. Blastocyst cell allocation variables were evaluated by T-test and developmental data were analysed with a multilevel random effects regression model.Main results and the role of chance: the total number of cells in blastocysts from aged mice was decreased (P < 0.05) relative to young mice due to a lower number of cells in the trophectoderm (mean ± SEM: 34.5 ± 2.1 versus 29.6 ± 1.0). Weekly body weight did not differ in male offspring, but an increase in body weight from Week 13 onwards was observed in Old-ET females (final body weight at post-natal Week 30: 38.5 ± 0.8 versus 33.4 ± 0.8 g, P < 0.05). Blood pressure was increased in Old-ET offspring at Weeks 9–15 in males (Week 9: 108.5 ± 3.13 versus 100.8 ± 1.5 mmHg, Week 15: 112.9 ± 3.2 versus 103.4 ± 2.1 mmHg) and Week 15 in females (115.9 ± 3.7 versus 102.8 ± 0.7 mmHg; all P < 0.05 versus Young-ET). The GTT results and organ allometry were not affected in male offspring. In contrast, Old-ET females displayed a greater (P < 0.05) peak glucose concentration at 30 min during the GTT (21.1 ± 0.4 versus 17.8 ± 1.16 mmol/l) and their spleen weight (88.2 ± 2.6 ± 105.1 ± 4.6 mg) and several organ:body weight ratios (g/g × 103) were decreased (P < 0.05 versus Young-ET), including the heart (3.7 ± 0.06 versus 4.4 ± 0.08), lungs (4.4 ± 0.1 versus 5.0 ± 0.1), spleen (2.4 ± 0.06 versus 3.2 ± 0.1) and liver (36.4 ± 0.6 versus 39.1 ± 0.9).Limitations, reasons for caution: results from experimental animal models cannot be extrapolated to humans. Nevertheless, they are valuable to develop conceptual models that can produce hypotheses for eventual testing in the target species (i.e. humans).Wider implications of the findings: our data show that offspring from mouse embryos from aged mothers can develop altered phenotypes during post-natal development compared with embryos from young mothers. Because all embryos were transferred into young mothers for the duration of pregnancy to normalize the maternal in vivo environment, our findings indicate that adverse programming via AMA is already established at the blastocyst stage. Whilst human embryos display increased aneuploidy compared with mouse, we believe our data have implications for women of AMA undergoing assisted reproduction, including surrogacy programmes.Study funding/competeing interest(s): this work was supported through the European Union FP7-CP-FP Epihealth programme (278418) to T.P.F. and the BBSRC (BB/F007450/1) to T.P.F. The authors have no conflicts of interest to declar

Movement in Ethiopia / Ethiopia in Movement: A Country in Change as Reflected by an Academic Event

By producing a rhetorical mirror effect in which the various facets of the past and present of Ethiopia are reflected, the word of ‘movement’ has defined the central theme of the Eighteenth International Conference of Ethiopian Studies (ICES 18 in abbreviation). This major academic event took place from Monday 29 October to Friday 2 November 2012 in the Chartered City of Dire Dawa, Ethiopia. It gathered 286 registered participants on the basis of the 335 papers selected by the organizing comm..

Walnut Creek and Squaw Creek Watersheds, Iowa: National Institute of Food and Agriculture–Conservation Effects Assessment Project

The goal of the Iowa National Institute of Food and Agriculture–Conservation Effects Assessment Project (NIFA–CEAP), Economic and Water Quality Effects of Multiple Conservation Practices in Three Midwest Watersheds, was to provide science-based information to policymakers concerning the water quality benefits and economic costs of implementing multiple agricultural conservation practices in these watersheds. The three primary watersheds were (1) Walnut Creek Watershed in south central Iowa and the Squaw Creek Watershed (which was the “control watershed” within the paired-watershed study), (2) Sny Magill Creek Watershed and Bloody Run Creek Watershed (which was also a “control watershed” within that paired-watershed study), and (3) the South Fork of the Iowa River Watershed in north central Iowa

The Microbial Rosetta Stone Database: A compilation of global and emerging infectious microorganisms and bioterrorist threat agents

BACKGROUND: Thousands of different microorganisms affect the health, safety, and economic stability of populations. Many different medical and governmental organizations have created lists of the pathogenic microorganisms relevant to their missions; however, the nomenclature for biological agents on these lists and pathogens described in the literature is inexact. This ambiguity can be a significant block to effective communication among the diverse communities that must deal with epidemics or bioterrorist attacks. RESULTS: We have developed a database known as the Microbial Rosetta Stone. The database relates microorganism names, taxonomic classifications, diseases, specific detection and treatment protocols, and relevant literature. The database structure facilitates linkage to public genomic databases. This paper focuses on the information in the database for pathogens that impact global public health, emerging infectious organisms, and bioterrorist threat agents. CONCLUSION: The Microbial Rosetta Stone is available at . The database provides public access to up-to-date taxonomic classifications of organisms that cause human diseases, improves the consistency of nomenclature in disease reporting, and provides useful links between different public genomic and public health databases

Transfer of Small Resting B Cells into Immunodeficient Hosts Results in the Selection of a Self-renewing Activated B Cell Population

We studied the role of bone marrow B cell production in the renewal of peripheral B cells and the feedback mechanisms that control the entry of newly formed B cells into the peripheral B cell pools. When resting lymph node B cells are injected into B cell–deficient hosts, a fraction of the transferred cells expands and constitutes a highly selected population that survives for prolonged periods of time by continuous cell renewal at the periphery. Although the number of donor B cells recovered is low, a significant fraction shows an activated phenotype, and the serum immunoglobulin (Ig)M levels are as in normal mice. This population of activated B cells is resistant to replacement by a new cohort of B cells and is able to feedback regulate both the entry of newly formed B cells into the peripheral pool and terminal differentiation. These findings suggest that peripheral B cell selection follows the first come, first served rule and that IgM-secreting cells are generated from a pool of stable activated B cells with an independent homeostasis

Dark matter-rich early-type galaxies in the CASSOWARY 5 strong lensing system

We study the strong gravitational lensing system number 5 identified by the CASSOWARY survey. In this system, a source at redshift 1.069 is lensed into four detected images by two early-type galaxies at redshift 0.388. The observed positions of the multiple images are well reproduced by a model in which the total mass distribution of the deflector is described in terms of two singular isothermal sphere profiles. By modelling the lens galaxy spectral energy distributions, we measure the lens luminous masses and stellar mass-to-light ratios. These values are used to disentangle the luminous and dark matter components in the vicinity of the multiple images. We estimate that the dark over total mass ratio projected within a cylinder centred on the primary lens and with a radius of 12.6 kpc is 0.8 +/- 0.1. We contrast these measurements with the typical values found at similar distances (in units of the effective radius) in isolated lens galaxies and show that the amount of dark matter present in these lens galaxies is almost a factor four larger than in field lens galaxies with comparable luminous masses. Data and models are therefore consistent with interpreting the lens of this system as a galaxy group. We infer that the overdense environment and dark matter concentration in these galaxies must have affected the assembly of the lens luminous mass components. We conclude that further multi-diagnostics analyses on the internal properties of galaxy groups have the potential of providing us a unique insight into the complex baryonic and dark-matter physics interplay that rules the formation of cosmological structures.Comment: 9 pages, 6 figures; accepted for publication in MNRA