СИНДРОМ ЛАЙЕЛЛА В СУДЕБНО-МЕДИЦИНСКОЙ И ПАТОЛОГО- АНАТОМИЧЕСКОЙ ПРАКТИКЕ

We report 9 clinicopathologic cases of Lyell’s syndrome, known as toxic epidermal necrolysis (TEN). Five deceased patients had dermal exposure to cow parsnip, grey mercury ointment or whitening agents. In 4 cases, TEN developed in the course of drug treatment as a part of polytherapy, and in one of them it was accompanied with the infection. All of TEN patients suffered from acute or chronic diseases, endogenous or exogenous intoxication, immunodeficiency.Приводятся 9 клинико-морфологических наблюдений синдрома Лайелла (токсического эпидермального некролиза, ТЭН). У 5 умерших были перкутанные варианты ТЭН в результате контакта с борщевиком, серой ртутной мазью, белилами. В 4 наблюдениях причиной ТЭН были лекарственные средства при политерапии и в одном из них в сочетании с инфекцией. У всех пациентов ТЭН развился на фоне хронических и острых заболеваний, эндо- и экзотоксикозов, иммунодефицита

LYELL’S SYNDROME IN MEDICO-LEGAL AND PATHOLOGICAL-ANATOMICAL PRACTICE

We report 9 clinicopathologic cases of Lyell’s syndrome, known as toxic epidermal necrolysis (TEN). Five deceased patients had dermal exposure to cow parsnip, grey mercury ointment or whitening agents. In 4 cases, TEN developed in the course of drug treatment as a part of polytherapy, and in one of them it was accompanied with the infection. All of TEN patients suffered from acute or chronic diseases, endogenous or exogenous intoxication, immunodeficiency

Aluminum-Alumina Composites: Part I: Obtaining and Characterization of Powders

The process of advanced aluminum-alumina powders production for selective laser melting was studied. The economically effective method of obtaining aluminum-alumina powdery composites for further selective laser melting was comprehensively studied. The aluminum powders with 10–20 wt. % alumina content were obtained by oxidation of aluminum in water. Aluminum oxidation was carried out at ≤200 °C. The oxidized powders were further dried at 120 °C and calcined at 600 °C. Four oxidation modes with different process temperatures (120–200 °C) and pressures (0.15–1.80 MPa) were investigated. Parameters of aluminum powders oxidation to obtain composites with 10.0, 14.5, 17.4, and 20.0 wt. % alumina have been determined. The alumina content, particle morphology, and particle size distribution for the obtained aluminum-alumina powdery composites were studied by XRD, SEM, laser diffraction, and volumetric methods. According to the obtained characteristics of aluminum-alumina powdery composites, they are suitable for the SLM process