Investigation on Acid-Resistant High-Silicon Iron (IV) : Corrosion Resistance to Sulphuric Acid

Corrosion tests were carried out on acid-resistant high-silicon iron in sulphuric acid with various concentrations and temperatures. The effects of the acid concentration, temperature and duration of test were discussed. The appearance of surface of specimen was also examined

Investigation on Acid-Resistant High-Silicon Iron (III) : Effects of Cooling Rate and Annealing on Mechanical Properties and Corrosion Resistance

The effects of the cooling rate of castings and annealing on the mechanical properties and corrosion resistance of acid-resistant high-silicon iron were studied. The variations in cooling rate bring about great changes in graphite structure and influence mechanical properties but hardly the corrosion resistance. It seems that the annealing of castings is important only with respect to the relief of internal casting stress

Novel c.2216T > C (p.I739T) Mutation in Exon 13 and c.1481T > A (p.L494X) Mutation in Exon 8 of MUT Gene in a Female with Methylmalonic Acidemia

We report herein a 1.5-year-old girl with methylmalonic acidemia (MMA) in whom two missense mutations were found: a novel I739T mutation located in exon 13 and the L494X mutation in exon 8. The results of organic acid test showed a pronounced increase in methylmalonate excretion with increased methylcitrate and 3-OH-propionate excretion, leading to a diagnosis of MMA, and Vitamin B12 administration was started. Analysis of the mut gene confirmed a T-to-A substitution at nucleotide position 1481 in exon 8 and a T-to-C substitution at nucleotide position 2216 in exon 13, leading to the amino acid isoleucine at position 739 being changed to threonine, resulting in c.2216T > C (p.I739T). The patient has now been on high-dose oral administration of Vitamin B12 and carnitine therapy (900 mg of levocarnitine chloride) for 5 years without experiencing further attacks, and her cognitive and motor development is normal. Further tests on residual enzyme activity, as well as experience with more cases, may shed light on the relationship between gene mutations and phenotypes in MMA