1,116 research outputs found
Mathematical Modeling of an Electromagnetic Forming System with Flat Spiral Coils as Actuator
This study presents mathematical modeling and calculation procedure for problems of electromagnetic forming of thin circular metal sheets using flat spiral coil as actuator. The method focuses specifically on the calculation of the electromagnetic field generated by the flat coil and analysis of the circuit that models the electromagnetic forming system. The flat coil is approximated by concentric circles carrying the current discharge from the capacitors. The calculation of electromagnetic force and magnetic couplings between the coil and metal sheet are made to the initial time, before the plastic deformation of the sheet. The method is based on the Biot-Savart law, and the solution of magnetic induction integral equations is performed by numerical methods specifically with the use of Matlab commercial software. A routine calculation, which models the problem as a set of differential equations was implemented in the Matlab, this provides important information that serves as feedback for system design. Free bulging experiments were performed to demonstrate a good relationship with the mathematical model predictions for electrical discharge current in the coil and induced currents in the metal sheet, behavior of the transient electromagnetic force between coil and workpiece and, distribution of magnetic field and electromagnetic density force along the coil. Also, achieved results showed that there is a strong dependence of the back electromagnetic force with respect to plate thickness for the system analyzed. The difference phase between the current induced in the coil and workpiece with higher negative peaks generate the back electromagnetic force
Proposal for a Test Bench for Electromagnetic Forming of Thin Metal Sheets
This paper presents a proposal to build a test bench for electromagnetic forming processes. The project considers the analysis of the electrical circuit and forces involved in the system for selection of low voltage capacitors, resistors, buses, main discharge switch and material choice for actuator s insulation and rigidity, considering also the manufacturing process of actuators and dies. Among the aspects considered for the design, energy efficiency has been prioritized by the use of non-conducting material to the dies. Main switches by mechanical contact and spark gap types were used and its wear and functionality was assessed. Free bulging experiments were performed with aluminium AA1100 plates for a system configured with a flat coil actuator. Test measurements of electric currents in the coil actuator with and without the workpiece as the secondary circuit were performed, as well as an evaluation of wear and functionality of the system. It is observed that the main switch discharge is one of the most critical items of the system
Fragility Curves for Thin-Walled Cold-Formed Steel Wall Frames Affected by Ground Settlements Due to Land Subsidence
Land subsidence phenomenon due to ground water withdrawal is a current problem in many places around the world, particularly in the shallows of Mexico. This causes ground differential settlements that affect structures, mainly dwellings and buildings based on reinforced concrete and masonry. Eventually, these structural materials do not exhibit an adequate performance beyond a certain level of angular distortion. This work presents the results about a study regarding the performance of thin-walled cold-formed steel wall frames with different sheathing systems affected by angular distortions simulating ground differential settlements due to land subsidence. The wall frames are composed by vertical (studs) and horizontal elements (tracks), with different sheathing systems: polystyrene, OSB, gypsum and calcium silicate. By means of experimental testing of wall frames subjected to monotonic lateral loads, the rotational stiffness was obtained for the wall frames with polystyrene. Likewise the rotational stiffness of the other wall frame systems was calculated based on the data provided by other authorâs publications. On the other hand, by means of numerical simulation, all the wall frame systems were modeled in structural analysis software, calibrating them based on the rotational stiffness. Also, the moment-rotation curves were calculated for the studs and tracks based on the direct strength method. A non-linear static pull down analysis was performed producing several degrees of angular distortion simulating ground settlements for all the wall frames sheathing systems. With the data acquired fragility curves were calculated according three levels of damage for the wall frames with different sheathing system
Multiple Sclerosis and Its Relationship with Oxidative Stress, Glutathione Redox System, ATPase System, and Membrane Fluidity
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) with a focus on inflammation, demyelination, and damage to axons leading to neurological deficits. MS pathology is associated with excessive reactive oxygen species (ROS) and generation of reactive nitrogen species (RNS), causing oxidative/nitrosative stress. Deregulation of glutathione homeostasis and alterations in glutathioneâdependent enzymes are implicated in MS. Reactive oxygen species enhance both monocyte adhesion and migration across brain endothelial cells. In addition, ROS can activate the expression of the nuclear transcription factorâkappa, which upregulates the expression of many genes involved in MS, such as tumor necrosis factorâα and nitric oxide synthase, among others, leading to mitochondrial dysfunction and energy deficits that result in mitochondrial and cellular calcium overload. Loss of mitochondrial membrane potential can increase the release of cytochrome c, one pathway that leads to neuronal apoptosis. Clinical studies suggest that omegaâ3 longâchain polyunsaturated fatty acids (PUFAs) including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have antiâinflammatory, antioxidant, and neuroprotective effects in MS and animal models of MS. Here, we review the relationship of oxidative stress, the glutathione redox system, the ATPase system, and membrane fluidity with the development of MS. In addition, we describe the main findings of a clinical trial conducted with relapsingâremitting MS patients who received a diet supplemented with 4âg/day of fish oil or olive oil. The effects of PUFAs supplementation on the parameters indicated above are analyzed in this work
Oxidative Stress and Parkinsonâs Disease: Effects on Environmental Toxicology
Epidemiological studies have found an increased risk of Parkinsonâs disease (PD) with environmental factors such as exposure to substances derived from industrial processes, use of agrochemicals, or living in a rural environment. The hypothesis that certain environmental toxins could be the source of the EP is supported by the discovery that chemicals such as herbicides paraquat, diquat, and the fungicide maneb are selectively toxic in nigrostriatal dopaminergic neurons. Also, one of the insecticides produced by plants, such as rotenone, and by-product of the synthesis of synthetic heroin MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) can be reproduced in animal models where neurochemicals, histopathological, and clinical characteristic of PD can be found. Interestingly, there are similarities in the chemical structure of paraquat and MPTP. Recent evidence exhibited that inflammation and oxidative stress play an essential role in the development of PD. So, in our laboratory we found that in an animal model melatonin decreases the products of lipid oxidation, nitric oxide metabolites, and the activity of cyclooxygenase 2, which are induced by an intraperitoneal injection of MPTP. This suggests that the neuroprotective effects of melatonin are partially attributed to its antioxidant scavenging and anti-inflammatory action
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