El patrimonio territorial: El territorio como recurso cultural y económico

The consideration of territory as a cultural and economic resource develops on its recent and on-going valuation as part of the historic and cultural heritage. This understanding as «heritage», rests on two main coordinates: the evolution suffered by the very conception of heritage, key element in modern occidental culture, and the progressive theoretical re-elaboration of the concept of «territory». Both collide, in the last few years, in a identification that allows to talk of territorial heritage, qualifying, thus, not only the construed object but the «construction» of space, beyond the building. This perspective, which is the one to justify this meeting, constitutes the starting point of this analysis.La consideración del territorio como un recurso cultural y económico deriva de su reciente y progresiva valoración como parte del patrimonio histórico y cultural. Este entendimiento como «patrimonio», reposa sobre dos principales coordenadas: la evolución habida en la concepción del propio patrimonio, elemento clave de la cultura occidental moderna, y la progresiva reelaboración teórica del concepto de «territorio». Ambas confluyen, en los últimos años, en una identificación que permite hablar de patrimonio territorial, cualificando, de este modo, no sólo el objeto edificado, sino la «construcción» del espacio, más allá del edificio. Esta perspectiva, que es la que sustenta este encuentro, constituye el punto de partida de este análisis

La Montaña Palentina

Producción CientíficaEstudio del medio físico, población, poblamiento, economía y nivel de vida de la Montaña Palentina, analizando los problemas existentes, potencialidades y propuestas de actuación.GeografíaEstudio realizado en el marco del Convenio firmado entre la Consejería de Economía y Hacienda de la Junta de Castilla y León y la Universidad de Valladolid con fecha 26 de febrero de 1999

IFBiD: Inference-Free Bias Detection

Also published online by CEUR Workshop Proceedings (CEUR-WS.org, ISSN 1613-0073)This paper is the first to explore an automatic way to detect bias in deep convolutional neural networks by simply look- ing at their weights. Furthermore, it is also a step towards understanding neural networks and how they work. We show that it is indeed possible to know if a model is biased or not simply by looking at its weights, without the model infer- ence for an specific input. We analyze how bias is encoded in the weights of deep networks through a toy example using the Colored MNIST database and we also provide a realistic case study in gender detection from face images using state- of-the-art methods and experimental resources. To do so, we generated two databases with 36K and 48K biased models each. In the MNIST models we were able to detect whether they presented a strong or low bias with more than 99% ac- curacy, and we were also able to classify between four levels of bias with more than 70% accuracy. For the face models, we achieved 90% accuracy in distinguishing between models biased towards Asian, Black, or Caucasian ethnicityThis work has been supported by projects: TRESPASSETN (MSCA-ITN-2019-860813), PRIMA (MSCAITN-2019-860315), BIBECA (RTI2018-101248-B-I00 MINECO/FEDER), and BB for TAI (PID2021-127641OB-I00 MICINN/FEDER). I. Serna is supported by a FPI fellowship from UAM

Plan piloto desarrollo de un programa de mentoría en el programa de doctorado “Formación en la Sociedad del Conocimiento” y creación de un espacio de trabajo colaborativo online

Memoria ID-027 Ayudas de la Universidad de Salamanca para la innovación docente, curso 2020-2021

Aproximación multidisciplinar a la supervisión del practicum en las carreras de educación, medicina, odontología, informática, comunicación y documentación

Memoria ID-035. Ayudas de la Universidad de Salamanca para la innovación docente, curso 2013-2014

ADAMTS13 recovery in acute thrombotic thrombocytopenic purpura after caplacizumab therapy

Caplacizumab prevents the interaction between von Willebrand factor and platelets and is used to treat immune thrombotic thrombocytopenic purpura (iTTP). Its administration has been associated with a delay in ADAMTS13 activity restoration after plasma exchange (PEX) suspension. We analyzed the outcomes of 113 iTTP episodes, 75 of which were treated with caplacizumab, in 108 patients from the Spanish Registry of Thrombotic Thrombocytopenic Purpura. Caplacizumab shortened the time to platelet count normalization and reduced PEX requirement, exacerbations, and relapses. There was no difference in the time to achieve ADAMTS13 activity ≥20% after PEX end between caplacizumab-treated and nontreated episodes (median [interquartile range], 14.5 [7.7-27.2] vs 13.0 [8.0-29.0] days, P = .653). However, considering the 36 episodes in which caplacizumab was started ≤3 days after iTTP diagnosis, the time for ADAMTS13 restoration from PEX end was higher than in those episodes in which caplacizumab was started >3 days after iTTP diagnosis (20.0 [12.0-43.0] vs 11.0 [3.5-20.0] days, P = .003) or than in non-caplacizumab-treated episodes (P = .033). This finding could be related to a significantly shorter duration of PEX in early caplacizumab-treated episodes than in late caplacizumab-treated episodes (5.5 [4.0-9.0] vs 15.0 [11.0-21.5] days, P < .001) or non-caplacizumab-treated episodes (11.0 [6.0-26.0] days, P < .001). There were no differences in time to ADAMTS-13 restoration from PEX start (28.0 [17.2-47.5], 27.0 [19.0-37.5] and 29.5 [15.2-45.0] days in early caplacizumab-treated, late caplacizumab-treated and non-caplacizumab-treated episodes). Early administered caplacizumab does not prevent the requirement for immunosuppression but has beneficial effects by shortening PEX requirement without major safety concerns.Peer reviewe

Recommendations for the Clinical Approach to Immune Thrombocytopenia: Spanish ITP Working Group (GEPTI)

© 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).Primary immune thrombocytopenia (ITP) is a complex autoimmune disease whose hallmark is a deregulation of cellular and humoral immunity leading to increased destruction and reduced production of platelets. The heterogeneity of presentation and clinical course hampers personalized approaches for diagnosis and management. In 2021, the Spanish ITP Group (GEPTI) of the Spanish Society of Hematology and Hemotherapy (SEHH) updated a consensus document that had been launched in 2011. The updated guidelines have been the reference for the diagnosis and management of primary ITP in Spain ever since. Nevertheless, the emergence of new tools and strategies makes it advisable to review them again. For this reason, we have updated the main recommendations appropriately. Our aim is to provide a practical tool to facilitate the integral management of all aspects of primary ITP management.Peer reviewe

El patrimonio territorial: El territorio como recurso cultural y económico

The consideration of territory as a cultural and economic resource develops on its recent and on-going valuation as part of the historic and cultural heritage. This understanding as «heritage», rests on two main coordinates: the evolution suffered by the very conception of heritage, key element in modern occidental culture, and the progressive theoretical re-elaboration of the concept of «territory». Both collide, in the last few years, in a identification that allows to talk of territorial heritage, qualifying, thus, not only the construed object but the «construction» of space, beyond the building. This perspective, which is the one to justify this meeting, constitutes the starting point of this analysis.La consideración del territorio como un recurso cultural y económico deriva de su reciente y progresiva valoración como parte del patrimonio histórico y cultural. Este entendimiento como «patrimonio», reposa sobre dos principales coordenadas: la evolución habida en la concepción del propio patrimonio, elemento clave de la cultura occidental moderna, y la progresiva reelaboración teórica del concepto de «territorio». Ambas confluyen, en los últimos años, en una identificación que permite hablar de patrimonio territorial, cualificando, de este modo, no sólo el objeto edificado, sino la «construcción» del espacio, más allá del edificio. Esta perspectiva, que es la que sustenta este encuentro, constituye el punto de partida de este análisis

Áreas de montaña: de la supervivencia a la integración

La montaña, espacio construido socialmente, no es, exclusivamente, un espacio rural. El desarrollo territorial de la montaña supone, desde época histórica, la consolidación de una jerarquía de asentamientos y estructuras sociales y de actividad diversas y complejas. Las actividades agrarias, ganaderas, forestales e incluso, las industriales, configuran los espacios de montaña. El patrimonio de las áreas rurales de montaña comprenden herencias diversas cuya superposición temporal y espacial componen el espacio heredado y le dan auténtica dimensión cultural. El artículo analiza la evolución de las políticas de desarrollo de las áreas de montaña en Europa y España, el tránsito de una visión agrarista de la montaña a un enfoque integral que supone la consideración de patrimonio territorial de estas áreas y su integración en las políticas de ordenación territorial, de escala regional, como una parte funcional del conjunto