3 research outputs found
Education for the Eradication of Poverty
Abstract: This study examines the possible education for the eradication of poverty in Nigeria. It defines poverty as a state pf shortage or deficiency of meeting basic needs. Majors causes of poverty are overpopulation, illiteracy, unemployment, environmental degradation and government insensitive to the welfare of the people. Effects of poverty include homelessness, malnutrition and starvation, illness, crime, violence and antisocial behaviour like Internet Fraud (Yahoo business) and Advance Fee Fraud Populace (419). Some poverty eradication strategies highlighted include: (i) Organisation of international workshops on eradication of poverty, (ii) Respect for human rights, (iii) Quality basic education for girls (iv) Meaningful contributions by NGOs, (v) Provision of jobs for the people. Some recommendations are made for the way forward
Interaction of RNA polymerase I transcription factors with a promoter in the nontranscribed spacer of rat ribosomal DNA.
The spacer promoter of the rat rDNA repeat consists of two functional domains: a core (proximal) element that is sufficient for transcription in vitro, and an upstream (distal) promoter element that increases the efficiency of transcription. Two of the transcription factors that interact with the 45S promoter also interact with the spacer promoter. Rat SL-1, is required for transcription of the spacer promoter by heterologous extracts, e.g. human, and rat SF-1 is required for efficient transcription in vitro. Order-of-addition experiments demonstrated that the preinitiation complex formed by these factors on the spacer promoter is not as stable as the complex formed on the 45S promoter. DNase 1 footprinting experiments demonstrated binding sites for rat SL-1 and SF-1 on the distal element of the spacer promoter. The topology of the domains of the spacer promoter may explain both the reduced stability of the preinitiation complex formed on that promoter and the lower efficiency of transcription of that promoter when compared to the 45S promoter