912 research outputs found

    Impact Analysis of Malware Based on Call Network API with Heuristic Detection Method

    Get PDF
    Malware is a program that has a negative influence on computer systems that don\u27t have user permissions. The purpose of making malware by hackers is to get profits in an illegal way. Therefore, we need a malware analysis. Malware analysis aims to determine the specifics of malware so that security can be built to protect computer devices. One method for analyzing malware is heuristic detection. Heuristic detection is an analytical method that allows finding new types of malware in a file or application. Many malwares are made to attack through the internet because of technological advancements. Based on these conditions, the malware analysis is carried out using the API call network with the heuristic detection method. This aims to identify the behavior of malware that attacks the network. The results of the analysis carried out are that most malware is spyware, which is lurking user activity and retrieving user data without the user\u27s knowledge. In addition, there is also malware that is adware, which displays advertisements through pop-up windows on computer devices that interfaces with user activity. So that with these results, it can also be identified actions that can be taken by the user to protect his computer device, such as by installing antivirus or antimalware, not downloading unauthorized applications and not accessing unsafe websites. &nbsp

    Mind the Gap: A Study in Global Development through Persistent Homology

    Full text link
    The Gapminder project set out to use statistics to dispel simplistic notions about global development. In the same spirit, we use persistent homology, a technique from computational algebraic topology, to explore the relationship between country development and geography. For each country, four indicators, gross domestic product per capita; average life expectancy; infant mortality; and gross national income per capita, were used to quantify the development. Two analyses were performed. The first considers clusters of the countries based on these indicators, and the second uncovers cycles in the data when combined with geographic border structure. Our analysis is a multi-scale approach that reveals similarities and connections among countries at a variety of levels. We discover localized development patterns that are invisible in standard statistical methods

    Vitamin D Prevents Endothelial Damage Induced by Increased Neutrophil Extracellular Traps Formation in Patients with Systemic Lupus Erythematosus

    Get PDF
    Aim: to investigate the effects of Vitamin D calcitriol/1,25(OH)2D3 on NETosis in systemic lupus erythematosus (SLE) patients with hypovitamin D. Methods: neutrophlis of five SLE patients with hypovitamin D were divided into 4 groups, P0 (0 nM/control), P1 (1 nM), P2 (10 nM), and P3 (100 nM) as cultured samples. Phorbol Myristate Acetate (PMA) was used to stimulate NETs formation. The supernatant was separated and cocultured with HUVECs. Externalization of Neutrophil Elastase (NE) and Myeloperoxidase (MPO) during NETosis was measured by immunofluorescence and ELISA respectively. Early and late apoptosis of endothelial cell was measured by flowcytometry using cell death kit (Annexin V and PI antibody). Results: this study showed significant decrease in early apoptosis with 10 nM of 1,25(OH)2D3 compared to control group. Significance of NE externalization found in all treatment groups (p<0.05), while MPO absorbance in the same tendency but not statistically significant. Further analysis also found a moderate positive correlation between NE externalizations with early apoptosis. Conclusion: vitamin D 1,25(OH)2D3 could reduce endothelial damage by decreasing NETosis activity. This result may reveal the possibility of Vitamin D as supplementary therapy for SLE patients with hypovitamin D to prevent endothelial damage. Key words: NETs, NE, MPO, 1,25(OH)2D3, HUVECs

    Under one roof? A population-based survey of patient use and preference for sexual health services

    Get PDF
    To compare patterns of population service use and preference in areas with and without one-stop shop services. A number of strategy documents have recommended adopting a more integrated approach to sexual health service provision. One proposed model of integration is one-stop shops, where services for contraception and sexually transmitted infections are provided under the same roof. Currently, the potential impact of one-stop shop services on patient service use and preference is unclear, particularly at a population level. Three different models of one-stop shop were studied: a dedicated young persons’ service, a specialist mainstream service, and an enhanced general practice. In each model, the one-stop shop site was matched to two control sites with traditional service provision. Random samples of male and female patients were selected from general practices close to either the one-stop shop or control sites. These patients received a postal survey asking about their use or preference for services for six sexual health needs. One-stop shop and control samples were compared using multivariate logistic regression. Of the 14 387 patients surveyed, 3101 (21.6%) responded. In the young persons’ model, few significant differences were found in service use or preference between those living in one-stop shop and control site areas. In the specialist services model, women in the one-stop shop area were significantly more likely to cite specialist services for emergency contraception and abortion advice, when compared to those served by non-integrated control services. In the general practice model, respondents in the one-stop shop area were significantly more likely to cite general practice for all six sexual health needs. Overall, general practice was the preferred service provider cited for all sexual health needs, except condoms and pregnancy tests. These findings are discussed in terms of their implications for the provision of integrated sexual health services. In addition, key methodological issues and future research possibilities are identified. © 2009, Cambridge University Press. All rights reserved

    (De)Localization in the Prime Schrodinger Operator

    Full text link
    It is reported a combined numerical approach to study the localization properties of the one-dimensional tight-binding model with potential modulated along the prime numbers. A localization-delocalization transition was found as function of the potential intensity; it is also argued that there are delocalized states for any value of the potential intensity.Comment: 7 pages, 4 figures; to be published in J. Phys. A: Math. Ge

    Charged Particles in a 2+1 Curved Background

    Full text link
    The coupling to a 2+1 background geometry of a quantized charged test particle in a strong magnetic field is analyzed. Canonical operators adapting to the fast and slow freedoms produce a natural expansion in the inverse square root of the magnetic field strength. The fast freedom is solved to the second order. At any given time, space is parameterized by a couple of conjugate operators and effectively behaves as the `phase space' of the slow freedom. The slow Hamiltonian depends on the magnetic field norm, its covariant derivatives, the scalar curvature and presents a peculiar coupling with the spin-connection.Comment: 22 page

    一言語聴覚士の臨床遍歴

    Get PDF
    回想General Articl
    corecore