Label-free imaging by stimulated parametric emission microscopy reveals a difference in hemoglobin distribution between live and fixed erythrocytes

Hieu M. Dang, Gen Omura, Toshiyuki Omano, Masatomo Yamagiwa, Shin'ichiro Kajiyama, Yasuyuki Ozeki, Kazuyoshi Itoh, and Kiichi Fukui "Label-free imaging by stimulated parametric emission microscopy reveals a difference in hemoglobin distribution between live and fixed erythrocytes," Journal of Biomedical Optics 14(4), 040506 (1 July 2009). https://doi.org/10.1117/1.320715

Prevalence of adrenal masses in Japanese patients with type 2 diabetes mellitus

<p>Abstract</p> <p>Introduction</p> <p>To date, there have been no reports on the prevalence of adrenal masses in type 2 diabetic patients. The present study aimed to evaluate the prevalence of adrenal incidentaloma in type 2 diabetic patients in Japan.</p> <p>Subjects</p> <p>We retrospectively evaluated the presence of adrenal masses using abdominal CT scans in 304 type 2 diabetic patients. In those with adrenal masses, we examined the hormone production capacity of the adrenal mass.</p> <p>Results</p> <p>Fourteen patients (4.6%) had an adrenal mass. Hormonal analysis identified one case as having subclinical Cushing's syndrome, two with primary aldosteronism. Eleven cases had non-functioning masses.</p> <p>Discussion</p> <p>The reported prevalence of adrenal incidentaloma in normal subjects is 0.6-4.0% in abdominal CT scan series. Our results show a relatively high prevalence of adrenal tumors in diabetic patients. On the other hand, the frequency of functional adenoma in diabetic patients is 21.4%, which is similar to that of normal subjects.</p> <p>Conclusion</p> <p>Although further studies are needed to evaluate the prevalence of adrenal tumors in diabetic patients, our data suggest that evaluation of the presence of adrenal masses may be needed in patients with type 2 diabetes mellitus.</p

〈Case Reports〉New catheter stent using a nelaton catheter for treatment of cervical stenosis in postmenopausal women with pyometra

[Abstract]　We developed a new catheter stent as a safe, easy and effective treatment method for cervical stenosis. Two postmenopausal women with pyometra were treated using a new catheter stent. The cervical canal is identified with a uterine sound under ultrasound guidance. A sterilized catheter stent using a nelaton catheter is then placed in the cervical canal for 3 months because of increasing re-stenosis of uterine cervix placing the another catheter within 2 months. Resolution of pyometra was achieved in both patients immediately after catheter stent insertion. At follow-up after removal of the tube, there was no evidence of recurrence of cervical stenosis. The new catheter stent can be placed for a long period and removed easily without any sutures or specialized instruments. There is no need for general anesthesia during our management procedure, which is beneficial in the office setting. This temporary catheter stent is both effective and safe in the treatment of cervical stenosis.Mituhashi, Youji, Ohmura, Gen, Amano, Youk

〈Case Reports〉Effective combination chemotherapy of taxanes and platinum in advanced uterine cervica cancer: a case report

[Abstract]　The prognosis of advanced cervical cancer remains poor. Recently, the significant activity of paclitaxel has been shown in advanced cervical cancers. We report a patient with advanced uterine cervical cancer who responded to neoadjuvant combination chemotherapy with taxanes and platinum. The patient was a 53-year old woman who presented with pollakisuria, lumbago, and pain in the anus and inguinal lesion, without genital bleeding. The findings indicated a clinical diagnosis of stage 4b disease with lung metastasis. We performed neoadjuvant combination chemotherapy with 7 courses of TC therapy (paclitaxel and carboplatin) and 7 courses of DP therapy (docetaxel and cisplatin) with a good effect.Mituhashi, Youji, Ohmura, Gen, Amano, Youk