PHYSICOCHEMICAL STUDIES OF MANGANESE (II) AND COPPER (II) COMPLEXES AND THEIR ADDUCT

 Bis(salicylaldehydato) manganese (II) and Bis(4,4,4-trifluoro-1-(2-Naphthyl)-1,3-butanedionato) copper(II),  their 2,2'-bipyridine, ethylenediamine, 1,10-phenanthroline and tetramethylethylenediamine adducts have been synthesized and characterized by metal analysis, FT-IR, UV–Visible, magnetic susceptibility and antimicrobial activity. The complexes and adducts were obtained as brown, yellow or light green colour. The metal analyses were in close agreement with the theoretical values expected. The infrared spectra of the manganese(II) complex revealed the coordination of salicylaldehyde through the carbonyl group and the hydroxyl group, while 2,2'-bipyridine, ethylenediamine, 1,10-phenanthroline and tetramethylethylenediamine coordinated to the metal through the nitrogen atoms. The magnetic moment data suggests low-spin octahedral geometry for [Mn(sal)2(H2O)2] (μeff = 2.14 B.M), high-spin octahedral geometries for [Mn(sal)2(en)].5H2O (μeff = 5.50 B.M), [Mn(sal)2(phen)] (μeff = 6.2 B.M),[Mn(sal)2bipy](μeff =5.95 B.M)  and [Mn(sal)2(tmen)](μeff =5.98 B.M.). The electronic measurements are indicative of a probable four-coordinate square planar geometry for [Cu(tfnb)2] while five-coordinate square pyramidal geometry are proposed for the copper(II) adducts. The complexes and adducts were screened against various bacteria and fungi. The copper complex and adducts were moderately active against fungal strain except [Cu(tfnb)2] and [Cu(tfnb)2en] in Aspergillus niger which showed pronounced activity and resistance respectivel

Oclusión espontánea de malformación arteriovenosa cerebral parcialmente embolizada: reporte de dos casos Spontaneous occlusion of previously cerebral embolized residual arteriovenous malformation: report of two cases

OBJETIVO: Mostrar dos casos de oclusión espontánea de remanente malformativo previamente embolizado y analizar sus probables causas. MÉTODO: Revisión retrospectiva de pacientes con malformaciones arteriovenosas cerebrales (MAV) embolizadas entre Enero de 1999 y Agosto de 2005 en nuestra institución y análisis de dos casos de oclusión de MAV remanentes. RESULTADOS: Se presentan dos casos de MAV tratadas por vía endovascular, con remanentes del nido malformativo post-embolización, que posteriormente en controles angiográficos presentan desaparición completa de las lesiones sin mediar otro tratamiento. CONCLUSIÓN: La oclusión espontánea de un remanente arteriovenoso es un hecho infrecuente. Se discuten diversos mecanismos relacionados.<br>OBJECTIVE: To report two cases of spontaneous occlusion of residual malformations that had previously been embolized and to analyze their probable causes. METHOD: Retrospective review of patients with embolized arteriovenous malformations (AVMs) between January 1999 and August 2005 in our institution and analysis of two cases of occlusion in residual AVMs. RESULTS: Two cases of AVMs that received endovascular treatment and had post-embolization residual nidus malformation, which in later angiographic controls showed a complete disappearance of the lesions without other treatment. CONCLUSION: The spontaneous occlusion of residual arteriovenous malformations is an infrequent occurrence. Several related mechanisms are discussed