Evaluation of hair growth promoting activity of petroleum ether extracts of Hemidesmus indicus Linn. (Seed) on Wistar Albino rats

In present investigation was carried out to screening of hair growth promoting potentiality of petroleum ether extract of Hemidesmus indicus Linn. (Seeds). Preliminary chemical tests and TLC analysis revealed the presence flavonoids and saponins. Hair growth promoting activity of petroleum ether of Hemidesmus indicus was screened by considering different parameters which included time taken for covering bald patch, length of hair produced, percentage of hair follicles in anagen and telogen phases, time of hair growth initiation and completion and level of minerals in blood. The petroleum ether extract of Hemidesmus indicus showed a very good hair growth promoting activity at a dose of 300 mg/kg which was comparable to that of 2% minoxidil. After 30 days of treatment with test and standard drugs it was observed that, time taken for covering the bald patch, hair growth initiation and completion time and quantitative hair growth were found to be comparable to that of the standard drug. An increase in percentage of hair follicles turning from telogen phase to anagen phase was noted. The control treated group of animals showed poor hair growth for all the parameters. Keywords:  Hemidesmus indicus Linn., Anagen, Catagen, Telogen, Minoxidil

Formulation and evaluation of new polyherbal germicidal toothpaste containing ajwain oil

The main object of the present research is to provide a formulation useful as natural herbal tooth paste which obviates the drawbacks of the earlier tooth pastes.And its to provide a good tooth paste which can give effective protection to teeth and free them from any toxicity or toxic residue and irritation when regularly used. It should be cosmetically acceptable having pleasant odour and should not leave stain on teeth or fingers after use. Brightening the teeth by removing stains would be a prerequisite of the formulation.Still another object of the present invention is highlight the potential of extract of ajwain seed in inhibiting  the activity of Streptococcus mutans bacteria which are major cause of dental caries. The study attributed presence of naphthalene derivative responsible for such protective antibiofilm activity. Ajwain oil is proven to cure tooth pain. Along with equal parts of clove oil and water, it is used as home remedy to floss mouth and treat tooth ache, bad breath and tooth decay. Keywords: Halitosis, Gingivitis and Periodontiti

Evaluation of hair growth promoting activity of petroleum ether extract of Abrus precatorius Linn. on Wistar Albino rats

In present investigation was carried out to screening of hair growth promoting potentiality of petroleum ether extract of Abrus precatorius leaf. Preliminary chemical tests and TLC analysis revealed the presence flavonoids and saponins. Hair growth promoting activity of petroleum ether of Abrus precatorius was screened by considering different parameters which included time taken for covering bald patch, length of hair produced, percentage of hair follicles in anagen and telogen phases, time of hair growth initiation and completion and level of minerals in blood. The petroleum ether extract of Abrus precatorius showed a very good hair growth promoting activity at a dose of 300 mg/kg which was comparable to that of 2% minoxidil. After 30 days of treatment with test and standard drugs it was observed that, time taken for covering the bald patch, hair growth initiation and completion time and quantitative hair growth were found to be comparable to that of the standard drug. An increase in percentage of hair follicles turning from telogen phase to anagen phase was noted. The control treated group of animals showed poor hair growth for all the parameters. Keywords: Abrus precatorius Linn, Anagen, Catagen, Telogen, Minoxidi