222 research outputs found

    Enabling Development; design of a the Single Seat Wintec Electric Vehicle.(SSWEV)

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    The research project is related to the single seat three-wheel electric vehicle. Due to the high consumption of the oil in New Zealand (NZ) which have a direct impact on the economy, the authorities are now looking for an alternative source to power the vehicles and revolutionize the transport industry. There is another motive behind the development of electric vehicle (EV) which is linked with the environmental conditions of the country. The Internal Combustion Engine (ICE) vehicles increase the air pollution in the country and due to which the global warming has become a serious issue. To reduce the global warming effect and air pollution the electric vehicles have become a strong candidate or choice for the transportation. This project covers the electric vehicle in three parts: the Road Legal Status of EV in New Zealand, the Battery Electric System(BES), and Vehicle Design. There are some limitations which are associated with electric vehicles such as legislation does not encourage the people to purchase an electric vehicle, and the manufacturers are still interested in ICE vehicles. The research project proposes the desired policy for the EV in New Zealand. The possible design of the EV is proposed which is modeled in SolidWorks. Furthermore, the entire battery electric system and its management is included in the report which describes the proposed Battery electric system for single-seat electric vehicle. The primary goal in developing the battery electric system of the EV was to ensure that it has long driving range. The current EV are struggling to achieve the long driving range. The design selected for the EV is Reverse-trike. The unique features include the shifting of the centre of mass of the more extensive position. This design provides more stability and traction to the vehicle as the weight shift is towards the front wheels of the car

    Native/Aboriginal Students use Natural Health Products for Health Maintenance More so than Other University Students

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    Background and aim: University student use of Natural Health Products (NHP) for health maintenance (HealthM) is assessed in Canada. We hypothesize greater use of NHP by Native/Aboriginal and female students. Demographic predictor variables and the top ten NHP used are determined. Methods: A cross-sectional survey of 963 students (n=212 Native/Aboriginal; n=751 non-Native/Aboriginal) was conducted. χ2 and Fisher’s exact tests analyzed group differences. Multiple logistic regressions determined predictor variables of NHP use. Results: Of 963 surveyed students, 268 (27.8%) used NHP for HealthM, while 695 students (72.2%) did not. More Native/Aboriginal students used commercial tobacco (47% vs. 13%, P\u3c0.001) and NHP (67% vs. 45%, P\u3c0.001) than non- Native/Aboriginal students. Gender was not associated with NHP use (P=0.527). Canadians used echinacea more than non-Canadians (Odds Ratio [OR]=4.96; 95% Confidence Interval [CI]: 1.2-21.0). Ginger (OR=0.39; 95% CI: 0.2-0.78) and garlic (OR=0.28; 95% CI: 0.13-0.6) were popular amongst non-Canadians. Native/Aboriginal students used homeopathics (OR=39.9; 95% CI: 8.6-185.4) and rat root (OR=56.73; 95% CI: 6.91-465.8). Chamomile was less used by males (OR=0.33; 95% CI: 0.13-0.83) and used more by upperclassmen (OR=2.6 95% CI: 1.3-5.3). Conclusion: Homeopathics and rat root are popular amongst Native/Aboriginal students. Garlic and ginger are popular amongst non-Canadians than Canadian students; however, more Canadians used echinacea for HealthM than non-Canadians. Chamomile is less popular amongst males. Commercial tobacco is used more by Native/Aboriginal students. Predictors of NHP use are: Native /Aboriginal and upperclassman

    Impact of tobacco smoking on oral microbiota – a case-control study.

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    Oral microbiota is a vital part of human microbiota, including bacterial, protozoa, viral and fungal species. Beneficial microbes form biofilms to form a first-line defense against harmful microorganisms. Tobacco smoking is considered a major environmental factor affecting the orodental microbiota. Smokers harbor more pathogenic microbes than non-smokers. In fact, cigarette smoking exposes the oral cavity to a large number of toxicants, perturbing the oral microbial ecology through various mechanisms. In Saudi Arabia, research on the impact of tobacco smoking on oral microbiota is still lacking. Therefore, this case-control study is an important addition to the literature in terms of tobacco use and its effects on oral microbiota and oral hygiene. 130 men were recruited for this study, including 65 smokers and 65 non-smokers. The following parameters were recorded for all 130 participants – age, weight, height and education. The aim of this study was to investigate and compare the effect of tobacco smoking on the oral microbiome of smokers and non-smokers. The majority of the smokers were young adults between the ages of 21 and 30 inclusive (n=27). The results show that excessive microorganism growth was seen in smokers to a greater degree than non-smokers (38.5% of smokers vs. 8.8% of non-smokers). Not surprisingly, a significant majority (85.3%) of non-smokers had moderate microorganism growth compared to only 53.8% of smokers. cigarette smoking facilitates excessive growth of oral microorganisms, predisposing smokers to various periodontal diseases. In fact, smoking perturbs the balance of oral microbiota, producing a viable environment for microbes to cause diseases. Further large scale prospective studies are required to determine the exact mechanism that causes tobacco to affect oral microbiota

    Age-Related EMG Responses Of The Biceps Brachii Muscle Of Young Adults

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    Although the effect of an Electromyographic (EMG) signal on the Biceps Brachii (BB) muscle is at the forefront of human movement analysis,there is limited information regarding the importance of the differences in the age-related EMG responses during contraction.The present study aimed to compare the BB muscle activity of three different groups of young adults divided based on age and to find a relationship between surface EMG and endurance time during isometric contraction.The EMG signal was recorded in 30 healthy right-arm-dominant young male subjects during a handgrip force task.The subjects were rationally divided into one of the three age groups (ten in each group):adolescents (‘A’;aged 17.3 ± 1.4 years), vicenarians (‘V’; 24.6 ± 2.1 years),and tricenarians (‘T’; 33.2 ± 1.1 years).The muscle activation during contraction was determined as the root mean square (RMS) EMG signal normalised to the peak RMS EMG signal during a 10-s isometric contraction.The statistical analysis included linear regression to examine the relationship between the EMG amplitude and the endurance time based on five levels of contraction [60%,70%,80%,90% and 100% of the maximal voluntary contraction (MVC)],repeated measures ANOVA to assess differences among the different age groups and the coefficient of variation (CoV) to investigate the steadiness of the EMG activation. The result shows that the early age groups exhibit higher and steadier muscle activity (V: 3.65 ± 0.42 mV,11.46% and A: 3.12 ± 0.29 mV,9.29%) compared with the elderly subjects (T: 2.78 ± 0.33 mV, 11.98%).The most important finding is that the linear slope coefficient for the EMG (amplitude) as a function of time for the muscle of the ‘V’ group (r2=0.591,P0.05) and ‘A’ groups (r2=0.203, P > 0.05).The results obtained in this study can be used to improve the current understanding of the mechanics and muscle functions of the BB muscle of individuals from different age groups during isometric contraction

    A Phytochemical Analysis, Microbial Evaluation and Molecular Interaction of Major Compounds of Centaurea bruguieriana Using HPLC-Spectrophotometric Analysis and Molecular Docking

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    Centaurea is one of the most important genera within the family Asteraceae. An investigation of the phytochemical composition of Centaurea bruguieriana using Gas-Chromatography coupled to Mass spectrometry (GC-MS) was performed. Antimicrobial activity was evaluated using the minimum inhibitory concentration method (MIC) and validated by molecular docking for the major compounds of the most active fraction (1,10-di-epi-cubenol and methyl 8-oxooctanoate) of C. bruguieriana against three bacterial receptors (TyrRS, DNA gyrase, and dihydrofolate reductase (DHFR)). Evaluation of antioxidant activity was conducted using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assays. High-performance liquid chromatography (HPLC) was used to identify and quantify the contents of major compounds from ethyl acetate fraction (luteolin 7-O-glucoside, chlorogenic acid, kaempferol and isorhamnetin). The antimicrobial activity test showed that the chloroform fraction was more active against all microbial strains. The results of the molecular docking of two major compounds from chloroform fraction showed that good affinities were made between 1,10-di-epi-cubenol and the three selected receptors (TyrRs: −6.0 Kcal/mol against −8.2 Kcal/mol obtained with clorobiocin (standard); DNA gyrase: −6.6 Kcal/mol against −9.1 Kcal/mole obtained with clorobiocin; DHFR: −7.4 Kcal/mol against −6.3 Kcal/mol obtained with SCHEMBL2181345 Standard). Antioxidant evaluation showed that the ethyl acetate fraction was the most active fraction in DPPH (IC50 49.4 µg/mL) and ABTS (IC50 52.8 µg/mL) models. HPLC results showed the contents of luteolin 7-O-glucoside (7.4 µg/mg), and chlorogenic acid (3.2 µg/mg). Our study demonstrated that C. bruguierana is a promising source of bioactive compounds

    A Phytochemical Analysis, Microbial Evaluation and Molecular Interaction of Major Compounds of Centaurea bruguieriana Using HPLC-Spectrophotometric Analysis and Molecular Docking

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    Centaurea is one of the most important genera within the family Asteraceae. An investigation of the phytochemical composition of Centaurea bruguieriana using Gas-Chromatography coupled to Mass spectrometry (GC-MS) was performed. Antimicrobial activity was evaluated using the minimum inhibitory concentration method (MIC) and validated by molecular docking for the major compounds of the most active fraction (1,10-di-epi-cubenol and methyl 8-oxooctanoate) of C. bruguieriana against three bacterial receptors (TyrRS, DNA gyrase, and dihydrofolate reductase (DHFR)). Evaluation of antioxidant activity was conducted using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assays. High-performance liquid chromatography (HPLC) was used to identify and quantify the contents of major compounds from ethyl acetate fraction (luteolin 7-O-glucoside, chlorogenic acid, kaempferol and isorhamnetin). The antimicrobial activity test showed that the chloroform fraction was more active against all microbial strains. The results of the molecular docking of two major compounds from chloroform fraction showed that good affinities were made between 1,10-di-epi-cubenol and the three selected receptors (TyrRs: −6.0 Kcal/mol against −8.2 Kcal/mol obtained with clorobiocin (standard); DNA gyrase: −6.6 Kcal/mol against −9.1 Kcal/mole obtained with clorobiocin; DHFR: −7.4 Kcal/mol against −6.3 Kcal/mol obtained with SCHEMBL2181345 Standard). Antioxidant evaluation showed that the ethyl acetate fraction was the most active fraction in DPPH (IC50 49.4 µg/mL) and ABTS (IC50 52.8 µg/mL) models. HPLC results showed the contents of luteolin 7-O-glucoside (7.4 µg/mg), and chlorogenic acid (3.2 µg/mg). Our study demonstrated that C. bruguierana is a promising source of bioactive compounds

    Sentiment analysis in geo social streams by using machine learning technique

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    Dissertation submitted in partial fulfilment of the requirements for the degree of Master of Science in Geospatial TechnologiesMassive amounts of sentiment rich data are generated on social media in the form of Tweets, status updates, blog post, reviews, etc. Different people and organizations are using these user generated content for decision making. Symbolic techniques or Knowledge base approaches and Machine learning techniques are two main techniques used for analysis sentiments from text. The rapid increase in the volume of sentiment rich data on the web has resulted in an increased interaction among researchers regarding sentiment analysis and opinion (Kaushik & Mishra, 2014). However, limited research has been conducted considering location as another dimension along with the sentiment rich data. In this work, we analyze the sentiments of Geotweets, tweets containing latitude and longitude coordinates, and visualize the results in the form of a map in real time. We collect tweets from Twitter using its Streaming API, filtered by English language and location (bounding box). For those tweets which don’t have geographic coordinates, we geocode them using geocoder from GeoPy. Textblob, an open source library in python was used to calculate the sentiments of Geotweets. Map visualization was implemented using Leaflet. Plugins for clusters, heat maps and real-time have been used in this visualization. The visualization gives an insight of location sentiments

    Impact of tobacco smoking on oral microbiota – a case-control study.

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    Oral microbiota is a vital part of human microbiota, including bacterial, protozoa, viral and fungal species. Beneficial microbes form biofilms to form a first-line defense against harmful microorganisms. Tobacco smoking is considered a major environmental factor affecting the orodental microbiota. Smokers harbor more pathogenic microbes than non-smokers. In fact, cigarette smoking exposes the oral cavity to a large number of toxicants, perturbing the oral microbial ecology through various mechanisms. In Saudi Arabia, research on the impact of tobacco smoking on oral microbiota is still lacking. Therefore, this case-control study is an important addition to the literature in terms of tobacco use and its effects on oral microbiota and oral hygiene. 130 men were recruited for this study, including 65 smokers and 65 non-smokers. The following parameters were recorded for all 130 participants – age, weight, height and education. The aim of this study was to investigate and compare the effect of tobacco smoking on the oral microbiome of smokers and non-smokers. The majority of the smokers were young adults between the ages of 21 and 30 inclusive (n=27). The results show that excessive microorganism growth was seen in smokers to a greater degree than non-smokers (38.5% of smokers vs. 8.8% of non-smokers). Not surprisingly, a significant majority (85.3%) of non-smokers had moderate microorganism growth compared to only 53.8% of smokers. cigarette smoking facilitates excessive growth of oral microorganisms, predisposing smokers to various periodontal diseases. In fact, smoking perturbs the balance of oral microbiota, producing a viable environment for microbes to cause diseases. Further large scale prospective studies are required to determine the exact mechanism that causes tobacco to affect oral microbiota

    Determination of Phenolic Compounds in Various Propolis Samples Collected from an African and an Asian Region and Their Impact on Antioxidant and Antibacterial Activities

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    The biological activities of propolis samples are the result of many bioactive compounds present in the propolis. The aim of the present study was to determine the various chemical compounds of some selected propolis samples collected from Palestine and Morocco by the High-Performance Liquid Chromatography–Photodiode Array Detection (HPLC-PDA) method, as well as the antioxidant and antibacterial activities of this bee product. The chemical analysis of propolis samples by HPLC-PDA shows the cinnamic acid content in the Palestinian sample is higher compared to that in Moroccan propolis. The results of antioxidant activity demonstrated an important free radical scavenging activity (2,2-Diphenyl-1-picrylhydrazyl (DPPH); 2,2′-azino-bis 3-ethylbenzothiazoline-6-sulphonic acid (ABTS) and reducing power assays) with EC50 values ranging between 0.02 ± 0.001 and 0.14 ± 0.01 mg/mL. Additionally, all tested propolis samples possessed a moderate antibacterial activity against bacterial strains. Notably, Minimum Inhibitory Concentrations (MICs) values ranged from 0.31 to 2.50 mg/mL for Gram-negative bacterial strains and from 0.09 to 0.125 mg/mL for Gram-positive bacterial strains. The S2 sample from Morocco and the S4 sample from Palestine had the highest content of polyphenol level. Thus, the strong antioxidant and antibacterial properties were apparently due to the high total phenolic and flavone/flavonol contents in the samples. As a conclusion, the activities of propolis samples collected from both countries are similar, while the cinnamic acid in the Palestinian samples was more than that of the Moroccan samples
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