SPATIAL ORGANIZATION OF INDUSTRIAL TOURISM OBJECTS: CASE OF THE KEMEROVO REGION – KUZBASS

In recent years, the industrialized regions of Russia have faced the need to diversify the economy and develop new industries. The advantage of such regions is that they can use their industrial heritage to develop primarily industrial tourism. The purpose of the article is to analyze the spatial organization of industrial tourism objects on the territory of the Kemerovo region – Kuzbass. The authors analyze the approaches to the essence of the concept of "industrial tourism", study international and Russian experience in the development of industrial areas and assess the state of industrial tourism in the region with the help of SWOT-analysis method. Authors also identify the potential objects of industrial tourism and analyze their spatial organization. With the help of the QGIS 3.20 program, thematic map-scheme of the location of industrial tourism objects has been made. The conclusions about the prospects and directions of development of industrial tourism in the Kemerovo region – Kuzbass are made

Teachers and Expression of Emotions in Digital Communication

This article introduces an empirical study of the way teachers express emotions during digital communication, both in typing and in video conferencing. The study involved 170 female and 20 male members of school and university teaching staff (mean age = 43.78 y.o). It relied on an authentic multiple-choice questionnaire, grid questions, and case tasks. The participants knew special online means of expressing emotions but seldom used them with students. At video conferences, they referred to the same methods of transmitting emotions as in real communication. The women and the school teachers were more emotional in the digital environment than the rest. The research revealed emotionally limited digital communication between teachers and students, which needs further research on how to develop the lacking competencies

Relationship between Epicardial and Coronary Adipose Tissue and the Expression of Adiponectin, Leptin, and Interleukin 6 in Patients with Coronary Artery Disease

Adipose tissue (AT) is an endocrine and paracrine organ that synthesizes biologically active adipocytokines, which affect inflammation, fibrosis, and atherogenesis. Epicardial and perivascular fat depots are of great interest to researchers, owing to their potential effects on the myocardium and blood vessels. The aim of the study was to assess the expression and secretion of adipocytokine genes in the AT of patients with coronary artery disease (CAD) and patients with aortic or mitral valve replacement. This study included 84 patients with CAD and 50 patients with aortic or mitral valve replacement. Adipocytes were isolated from subcutaneous, epicardial (EAT), and perivascular AT (PVAT), and were cultured for 24 h. EAT exhibited the lowest level of adiponectin gene expression and secretion, regardless of nosology, and high expression levels of the leptin gene and interleukin-6 (IL-6). However, EAT adipocytes in patients with CAD were characterized by more pronounced changes in comparison with the group with heart defects. High leptin and IL-6 levels resulted in increased pro-inflammatory activity, as observed in both EAT and PVAT adipocytes, especially in individuals with CAD. Therefore, our results revealed the pathogenetic significance of alterations in the adipokine and cytokine status of adipocytes of EAT and PVAT in patients with CAD

Prevalence of Clostridium perfringens and Detection of Its Toxins in Meat Products in Selected Areas of West Kazakhstan

Objectives. The current study aimed to investigate the prevalence of Clostridium perfringens in meat products at meat fairs in four cities of West Kazakhstan from April to October 2021. Methods. In total, 240 samples were collected and subsequently examined for the presence of Clostridium perfringens and its associated toxins using a standard culture method and multiplex PCR assay. Results. In the 240 samples, 67 (30%) tested positive for Clostridium perfringens. All isolates were classified as biotype A with the ability to produce α toxin. The prevalence of Clostridium perfringens was found in almost all types of meat products tested. Beef samples 20/40 (50%) were found the most contaminated with a pathogen, followed by minced lamb 16/40 (40%), ground beef 11/40 (27.5%), lamb 9/40 (22.5%), beef intestines 7/40 (17.5%) and lamb intestines 4/40 (10%). Conclusions. The outcomes of our study demonstrated the high contamination rate of Clostridium perfringens in local meat products. This study is also the first survey on Clostridium perfringens prevalence in meats in Kazakhstan. The findings in this report will enhance knowledge of epidemiology and help develop coordinated actions to prevent and control possible food poisoning outbreaks