Early Localization of Bronchogenic Cancerous/Precancerous Lesions With Lung Imaging Fluorescence Endoscope

The result of the clinical trial using the lung imaging fluorescence endoscope (LIFE) was reported. A total of 77 biopsy confirmed sites from 30 patients were evaluated. The sensitivity for metaplasia detection by the LIFE system was 96% compared to 28% by conventional bronchoscopy. The LIFE system was found to be useful in detecting subtle cancerous/precancerous lesions

Alpha-fetoprotein-producing primary lung carcinoma: A case report

Alpha-fetoprotein (AFP)-producing lung adenocarcinoma is a rare type of lung cancer, with its characteristics not yet fully clarified. We recently encountered a case of this type of lung cancer. The patient was a 69-year-old man who consulted an internist with the chief complaint of epigastric pain. Chest X-ray and CT revealed a lobulated mass measuring 70 mm in diameter in the right lower lung field and a metastasis in the right hilar lymph nodes. Of the tumor markers, the serum AFP was elevated (4620 ng/ml), and the serum carcinoembryonic antigen and carbohydrate antigen 19-9 were also slightly elevated. Transbronchial lung biopsy revealed the diagnosis of lung cancer. Under thoracoscopic assistance, right lower lobectomy + mediastinal lymph node dissection was carried out. Immunostaining showed the tumor cells to be AFP-positive. The tumor was thus diagnosed as an AFP-producing lung adenocarcinoma. The patient followed an uneventful clinical course after the surgery, with serum AFP decreasing to the normal range by about 2 weeks after the surgery. As of this writing, no sign of tumor recurrence has been noted. This case is presented here with a review of the literature

FLUORESCENCE PHOTODIAGNOSIS IN TUMORS USING LASERS

No abstract availabl