6 research outputs found
Smart museum of everyday life history in Petrozavodsk State University: Software design and implementation of the semantic layer
Since 2016 a smart museum of everyday life history has been developed within the History Museum of Petrozavodsk State University. This R&D project aims at solutions to the two important problems for creating a digital service-oriented environment for museum visitors and personnel: 1) offering personal recommendations on the museum collection with the use of semantic ranking methods and in context of the user and exhibition, 2) collaborative addition of information sources and their semantic annotation within the museum collection. Such solutions form the semantic layer of smart museum environment. This paper introduces our a) system design models for agent- based programming of museum information services, b) ranking models for semantic data mining in historical and cultural heritage domain. Our software implementation demonstrates the feasibility of the proposed models in respect to the user mobility, service personalization, and collaborative work opportunity
Immunoglobulin, glucocorticoid, or combination therapy for multisystem inflammatory syndrome in children: a propensity-weighted cohort study.
BACKGROUND: Multisystem inflammatory syndrome in children (MIS-C), a hyperinflammatory condition associated with SARS-CoV-2 infection, has emerged as a serious illness in children worldwide. Immunoglobulin or glucocorticoids, or both, are currently recommended treatments. METHODS: The Best Available Treatment Study evaluated immunomodulatory treatments for MIS-C in an international observational cohort. Analysis of the first 614 patients was previously reported. In this propensity-weighted cohort study, clinical and outcome data from children with suspected or proven MIS-C were collected onto a web-based Research Electronic Data Capture database. After excluding neonates and incomplete or duplicate records, inverse probability weighting was used to compare primary treatments with intravenous immunoglobulin, intravenous immunoglobulin plus glucocorticoids, or glucocorticoids alone, using intravenous immunoglobulin as the reference treatment. Primary outcomes were a composite of inotropic or ventilator support from the second day after treatment initiation, or death, and time to improvement on an ordinal clinical severity scale. Secondary outcomes included treatment escalation, clinical deterioration, fever, and coronary artery aneurysm occurrence and resolution. This study is registered with the ISRCTN registry, ISRCTN69546370. FINDINGS: We enrolled 2101 children (aged 0 months to 19 years) with clinically diagnosed MIS-C from 39 countries between June 14, 2020, and April 25, 2022, and, following exclusions, 2009 patients were included for analysis (median age 8路0 years [IQR 4路2-11路4], 1191 [59路3%] male and 818 [40路7%] female, and 825 [41路1%] White). 680 (33路8%) patients received primary treatment with intravenous immunoglobulin, 698 (34路7%) with intravenous immunoglobulin plus glucocorticoids, 487 (24路2%) with glucocorticoids alone; 59 (2路9%) patients received other combinations, including biologicals, and 85 (4路2%) patients received no immunomodulators. There were no significant differences between treatments for primary outcomes for the 1586 patients with complete baseline and outcome data that were considered for primary analysis. Adjusted odds ratios for ventilation, inotropic support, or death were 1路09 (95% CI 0路75-1路58; corrected p value=1路00) for intravenous immunoglobulin plus glucocorticoids and 0路93 (0路58-1路47; corrected p value=1路00) for glucocorticoids alone, versus intravenous immunoglobulin alone. Adjusted average hazard ratios for time to improvement were 1路04 (95% CI 0路91-1路20; corrected p value=1路00) for intravenous immunoglobulin plus glucocorticoids, and 0路84 (0路70-1路00; corrected p value=0路22) for glucocorticoids alone, versus intravenous immunoglobulin alone. Treatment escalation was less frequent for intravenous immunoglobulin plus glucocorticoids (OR 0路15 [95% CI 0路11-0路20]; p<0路0001) and glucocorticoids alone (0路68 [0路50-0路93]; p=0路014) versus intravenous immunoglobulin alone. Persistent fever (from day 2 onward) was less common with intravenous immunoglobulin plus glucocorticoids compared with either intravenous immunoglobulin alone (OR 0路50 [95% CI 0路38-0路67]; p<0路0001) or glucocorticoids alone (0路63 [0路45-0路88]; p=0路0058). Coronary artery aneurysm occurrence and resolution did not differ significantly between treatment groups. INTERPRETATION: Recovery rates, including occurrence and resolution of coronary artery aneurysms, were similar for primary treatment with intravenous immunoglobulin when compared to glucocorticoids or intravenous immunoglobulin plus glucocorticoids. Initial treatment with glucocorticoids appears to be a safe alternative to immunoglobulin or combined therapy, and might be advantageous in view of the cost and limited availability of intravenous immunoglobulin in many countries. FUNDING: Imperial College London, the European Union's Horizon 2020, Wellcome Trust, the Medical Research Foundation, UK National Institute for Health and Care Research, and National Institutes of Health
Demo: Smart Services for the History Museum of Petrozavodsk State University
Smart museum of everyday life history within the History Museum of Petrozavodsk State University is a smart space-based system implemented using the Smart-M3 platform. This demo presents the smart services for the History Museum of Petrozavodsk State University: Visit service, Exhibition service, and Enrichment service. These smart services realize the semantic layer in the smart museum environment as a multiagent service-oriented information system deployed on the top of museum information systems. Museum personnel and visitors can directly access the multi-agent system and consume services using Personnel client and Visitor client
Smart service efficiency: Evaluation of cultural trip planning service
Nowadays the amount of “smart” services in e-Tourism grows rapidly. This is due to widespread using mobile devices with new input methods and large amount of digital data. Together with that, the smart services require complex methods and high cost of their creation. Thereby we have relevant problem of estimating smart service's efficiency. This paper presents evaluation of Cultural trip planning service based on defined smart attributes. For each of used attributes the execution scenario, ordinary service for comparison and used estimates are defined. Each estimate is calculated with taking into account the user experience. The evaluation results allow to compare Cultural trip planning service with some ordinary services
A smart space-based design of semantic layer for advancing museum information services
Nowadays many museums are being transformed to some “smart” variants: a cultural space in a digitally-equipped environment is formed where cultural heritage knowledge can be easily and collaboratively usable and creatable by interested visitors as well as by professionals. By using such innovative technologies as Internet of Things (IoT) and Smart Spaces it is possible to shorten the distance between museum exhibits and collected historical information on one side and consumers and providers of this information on the other side. In this paper, we study the smart museum concept for development of software that realizes connection between the involved actors and shared cultural heritage knowledge. Our research and development are focused on designing a semantic layer in the form of a software infrastructure. This infrastructure is a middleware on top of which such advanced museum information services can be constructed as personal visit planning, virtual exhibition preparation, and collaborative enrichment the museum collection. We introduce a suit of smart space-based solutions to create this type of software infrastructures. The generic solutions are theoretically analyzed based on the case study of the History Museum of Petrozavodsk State University (PetrSU)
Towards an understanding of smart service: The case study for cultural heritage e-Tourism
e-Tourism covers a wide niche of the digital services market. The existing services, although being presented in the large amount in today's Internet, do not achieve high intelligence level. The user still needs to perform a lot of operations manually: to solve a given problem she/he finds and accesses appropriate Internet services or uses mobile applications. A lot of information fragments are linked by the user her/himself, in the mind. In this paper, we discuss the problem of smart service development for the e-Tourism domain. The considered use-case scenario comes from cultural heritage tourism, which is an area of growing application interest We identify smart service attributes that allow a service to achieve a new level of the intelligence. The user becomes more focused on the substantial aspects of solving the problem. We contribute architectural solutions to service design. For the given use-case we show how the service-oriented system can be implemented in the form of a smart space deployed on user-surrounding devices based on the usage of external Internet services and multiple data sources