Diarrhoeal Disease Morbidity, Risk Factors and Treatments in a Low Socioeconomic Area of Ilorin, Kwara State, Nigeria

A 12-month diarrhoeal disease surveillance was carried out in a sample of 351 child-en under 3 years of age in a low - income traditional area of llorín, Nigeria to determine whether sociodemographic characteristics, including age of the child, sex, parity, mother's education, occupation, mother's age and household kitchen, were associated with the incidence of acute diarrhoea. Bivariate and multivariate analyses were used to determine association. Results indicated that only the age of the child and the type of kitchen used by the household had a significant association with diarrhoea. Diarrhoeal incidence decreases with the child's age while households with a private kitchen had a significantly lower incidence rate than those without a kitchen. This finding emphasises the importance of good hygiene in reducing the risk of having diarrhoea. Three common treatments applied by mothers are ORS (used in 14.8% of diarrhoea days), antibiotics (54.5%) and local herbs (27.7%). The younger a child is the more likely that ORS and antibiotics will be administered during diarrhoea. About 53% of the antibiotic use was by self medication while 40% were prescribed by the clinics. The need for educational campaigns to discourage the inappropriate use of antibiotics was emphasised. Key words'. Diarrhoea, Infantile; Risk factors; Diarrhoea morbidity; Diarrhoea mortality; Socioeconomic factors

EFFECT OF VITAMIN E ON SPERM AND OXIDATIVE STRESS PARAMETERS OF WEST AFRICAN DWARF GOAT BUCKS

The aim of the present study was to determine the effect of supplementation of vitamin E on sperm and oxidative stress parameters in West African Dwarf goat bucks. The bucks were allocated to 4 treatments consisting of 0 mg, 15 mg, 30 mg and 45 mg of vitamin E. At the end of 30 days consecutive administration of vitamin E, semen and blood samples were collected and evaluated for sperm and oxidative stress parameters. The results showed that sperm motility, acrosome integrity, membrane integrity and live spermatozoa; seminal Malondialdehyde (MDA), arginase activity and leukocytes; and serum MDA and testosterone were similar in all the levels of inclusion and comparable to the control. However, higher arginase activities were observed in all the levels of vitamin E compared to the control while 15 mg of vitamin E had higher percentage of sperm abnormality compared to other treatments and the control. The findings indicated that the levels of vitamin E used did not have beneficial effect on the sperm and oxidative stress parameters. Further study of higher levels of vitamin E is therefore necessary to ascertain the appropriate level required for optimal improvement in these parameters