Fertility Cancer and Hereditary Risks in Soil Sample of Nasarawa, Nasarawa State, Nigeria

A survey of Fertility Cancer and Hereditary Risks in Soil Sample of Nasarawa was carried out. This study assessed the level of Fertility Cancer and Hereditary Risks in some part of Nasarawa using the gamma-ray spectrometry. The mean concentration for 40K was 645.29 ± 07.32 Bq/kg, for 226Ra was 28.43 ± 4.8422 Bq/Kg and for 232Th was 66.84 ± 2.0201 Bq/Kg. The average effective dose due to the ingestion was 0.36±0.1µSv/y which was approximately 1000 times lower than the world average effective dose. Radium equivalent activity Raeq (Bq/kg), alpha index and total cancer risk were found to be 161.44±8.08 Bq/kg, 0.142±0.02 and (0.21±0.05) ×10-5 respectively. UNSCEAR/ USEPA stipulated that; radium equivalent activity, alpha index, effective dose and total cancer risk should not exceed the limit of 370 Bq/kg, unity, 300 µSv/y and 1 ×10-4 respectively. Hence the values obtained in this work were within the acceptable limits. This implies that the ingestion or inhalation of soil is not associated with any radiological risk of concern

Morphometric Characteristics of the Lower Orashi River, Niger Delta Region, Nigeria

The study examined the spatial analysis of the morphometric characteristics of the Lower Orashi River, Niger Delta Region, Nigeria. The river course was segmented into 30 equal distances of 4.8m from each other and at each point, the morphometric parameters like width, depth, and flow velocity. The discharge was measured from these parameters. Descriptive and inferential statistics were employed for data analysis while results are presented using tables and graphs. Results showed that width of the river ranged from 77.90m to 2788.00m with the mean width of 318.83m. The depth ranged from 2.10 to 7.60m with the mean depth recording 4.14m as it was higher at the upper section of the river while it becomes lower as it is entering the Atlantic Ocean. Furthermore, width was significantly correlated with the depth (r= -0.556, p<0.05), cross sectional area (r= 0.989, p<0.05) and discharge (r= 0.987, p<0.05).  Also, elevation was significantly correlated with cross sectional area (r= -0.506, p<0.05) and discharge (r = -0.511, p<0.05). More importantly, the cross sectional area was correlated with discharge (r=0.995, p<0.05). The study concluded that there is significant variation existing in the morphometric parameters namely width, elevation, cross sectional area and discharge among the segments along Orashi River. The study therefore recommended that the water course should be reduced of human activities to reduce the rate of soil loss or discharge and to boost the river floor with adequate morphological property

Harnessing History: Narratives, Identity and Perceptions of Russia's Post-Soviet Role

Russian political elites have long been aware of the power of myths to forge national unity. However, the past six or seven years have seen core myths increasingly situated within a highly selective narrative of Russian history. This narrative is accepted as contextual information for policy discussion, and so sets cognitive parameters for evaluations of Russia's history, identity and role. This standard narrative of Russian history prioritises the state, supports gradualism and continuity, and dramatically reduces the potential for re‐conceptualising Russia's role in contemporary international relations

'Concrete freedom' : C.L.R. James on culture and black politics

This article aims to provide a synoptic account of the cultural writings of the West Indian intellectual and activist C.L.R. James. I aim to make a case for greater recognition of his work among cultural sociologists. I go on to show how James’ original, historicising account of cultural forms relates closely to his wider political interventions including, specifically, his ground-breaking discussion of mid-twentieth century black politics in America

Distribution of a Knockdown Resistance Mutation (L1014S) in Anopheles gambiae s.s. and Anopheles arabiensis in Western and Southern Kenya

In Kenya, insecticide-treated mosquito nets (ITNs) distributed to pregnant women and children under 5 years old through various programs have resulted in a significant reduction in malaria deaths. All of the World Health Organization-recommended insecticides for mosquito nets are pyrethroids, and vector mosquito resistance to these insecticides is one of the major obstacles to an effective malaria control program. Anopheles gambiae s.s. and Anopheles arabiensis are major malaria vectors that are widely distributed in Kenya. Two point mutations in the voltage-gated sodium channel (L1014F and L1014S) are associated with knockdown resistance (kdr) to DDT and pyrethroids in An. gambiae s.s. While the same point mutations have been reported to be rare in An. arabiensis, some evidence of metabolic resistance has been reported in this species. In order to determine the distribution of the point mutation L1014S in An. gambiae s.s. and An. arabiensis in southern and western Kenya, we collected larvae and screened for the mutation by DNA sequencing. We found high allelic and homozygous frequencies of the L1014S mutation in An. gambiae s.s. The L1014S mutation was also widely distributed in An. arabiensis, although the allelic frequency was lower than in An. gambiae s.s. The same intron sequence (length: 57 base) found in both species indicated that the mutation was introgressed by hybridization. The allelic frequency of L1014S was higher in both species in western regions, demonstrating the strong selection pressure imposed by long-lasting insecticide-treated nets (LLITN)/ITN on the An. gambiae s.s. and An. arabiensis populations in those areas. The present contribution of the L1014S mutation to pyrethroid resistance in An. arabiensis may be negligible. However, the homozygous frequency could increase with continuing selection pressure due to expanded LLITN coverage in the future

Developing Global Maps of the Dominant Anopheles Vectors of Human Malaria

Simon Hay and colleagues describe how the Malaria Atlas Project has collated anopheline occurrence data to map the geographic distributions of the dominant mosquito vectors of human malaria

Optimizing Blood Transfusion Service Delivery across the West Africa Sub-Region

The sub-continent of West Africa is made up of 16 countries: Benin, Burkina Faso, Cape Verde, Ghana, Guinea, Guinea-Bissau, Ivory Coast, Liberia, Mali, Mauritania, Niger, Nigeria, Senegal, Sierra Leone, The Gambia and Togo. As of 2018, the population of the sub-continent was estimated at about 381 million. The main challenge associated with blood transfusion service delivery across the sub-region concerns adequacy and safety. In this chapter, we highlighted the challenges associated with the delivery of a quality blood transfusion service in countries in the sub-region including: implementation of component therapy rather than whole blood transfusion, effective cold chain management of blood and blood products, alloimmunization prevention, implementation of column agglutination and automation rather than the convention manual tube method in blood transfusion testing, effective management of major haemorrhage, optimization of screening for transfusion transmissible infections, optimizing blood donation, implementation of universal leucodepletion of blood and blood products, effective management of transfusion-dependent patients, pre-operative planning and management of surgical patients, management of Rhesus D negative pregnancy and women with clinically significant alloantibodies, implementation of haemovigilance system, implementation of alternatives to allogenic blood, availability and use of specialized blood products, optimizing safe blood donation, enhancing blood transfusion safety, operating a quality management system-based blood transfusion service and implementation of non-invasive cell-free foetal DNA testing. There is the urgent need for the implementation of evidence-based best practices in blood transfusion service delivery across the sub-region to allow for excellent, safe, adequate and timely blood transfusion service delivery across the sub-region

The dominant Anopheles vectors of human malaria in Africa, Europe and the Middle East: occurrence data, distribution maps and bionomic précis

<p>Abstract</p> <p>Background</p> <p>This is the second in a series of three articles documenting the geographical distribution of 41 dominant vector species (DVS) of human malaria. The first paper addressed the DVS of the Americas and the third will consider those of the Asian Pacific Region. Here, the DVS of Africa, Europe and the Middle East are discussed. The continent of Africa experiences the bulk of the global malaria burden due in part to the presence of the <it>An. gambiae </it>complex. <it>Anopheles gambiae </it>is one of four DVS within the <it>An. gambiae </it>complex, the others being <it>An. arabiensis </it>and the coastal <it>An. merus </it>and <it>An. melas</it>. There are a further three, highly anthropophilic DVS in Africa, <it>An. funestus</it>, <it>An. moucheti </it>and <it>An. nili</it>. Conversely, across Europe and the Middle East, malaria transmission is low and frequently absent, despite the presence of six DVS. To help control malaria in Africa and the Middle East, or to identify the risk of its re-emergence in Europe, the contemporary distribution and bionomics of the relevant DVS are needed.</p> <p>Results</p> <p>A contemporary database of occurrence data, compiled from the formal literature and other relevant resources, resulted in the collation of information for seven DVS from 44 countries in Africa containing 4234 geo-referenced, independent sites. In Europe and the Middle East, six DVS were identified from 2784 geo-referenced sites across 49 countries. These occurrence data were combined with expert opinion ranges and a suite of environmental and climatic variables of relevance to anopheline ecology to produce predictive distribution maps using the Boosted Regression Tree (BRT) method.</p> <p>Conclusions</p> <p>The predicted geographic extent for the following DVS (or species/suspected species complex*) is provided for Africa: <it>Anopheles </it>(<it>Cellia</it>) <it>arabiensis</it>, <it>An. </it>(<it>Cel.</it>) <it>funestus*</it>, <it>An. </it>(<it>Cel.</it>) <it>gambiae</it>, <it>An. </it>(<it>Cel.</it>) <it>melas</it>, <it>An. </it>(<it>Cel.</it>) <it>merus</it>, <it>An. </it>(<it>Cel.</it>) <it>moucheti </it>and <it>An. </it>(<it>Cel.</it>) <it>nili*</it>, and in the European and Middle Eastern Region: <it>An. </it>(<it>Anopheles</it>) <it>atroparvus</it>, <it>An. </it>(<it>Ano.</it>) <it>labranchiae</it>, <it>An. </it>(<it>Ano.</it>) <it>messeae</it>, <it>An. </it>(<it>Ano.</it>) <it>sacharovi</it>, <it>An. </it>(<it>Cel.</it>) <it>sergentii </it>and <it>An. </it>(<it>Cel.</it>) <it>superpictus*</it>. These maps are presented alongside a bionomics summary for each species relevant to its control.</p