1 research outputs found
Polyglucosan bodies in the prostatic stromal smooth muscles of aged dogs
Polyglucosan bodies (PGB) in the prostate of
aged dogs without neurological signs were examined by
light microscopy, histochemistry and immunohistochemistry. Prostatic PGB were round or oval and slightly
basophilic. Most of the bodies were situated within the
stromal smooth muscle cells. PGB were intensely
positive for PAS, Best’s carmine, Lugol’s iodine and
Grocott’s methenamine silver method. Moreover, canine
prostatic PGB were immunoreactive for monoclonal
antibodies raised against human polyglucosan. The
frequency of PGB in the smooth muscle cells was
significantly correlated with the age of dogs. The
occurrence of PGB in the canine prostate might be a
non-specific finding related to ageing