25 research outputs found

    Ecohealth and resilience thinking : a dialog from experiences in research and practice

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    Resilience thinking and ecosystems approaches to health (EAH), or ecohealth, share roots in complexity science, although they have distinct foundations in ecology and population health, respectively. The current articulations of these two approaches are strongly converging, but each approach has its strengths. Resilience thinking has developed theoretical models to the study of social– ecological systems, whereas ecohealth has a vast repertoire of experience in dealing with complex health issues. With the two fields dovetailing, there is ripe opportunity to create a dialog centered on concepts that are more thoroughly developed in one field, which can then serve to advance the other. In this article, we first present an overview of the ecohealth and resilience thinking frameworks before opening a dialog centered on seven themes that have strong potential for cross-pollination between the two approaches: scale interactions, regime shifts, adaptive environmental management, social learning, participation, social and gender equity, and knowledge to action. We conclude with some future research suggestions for those interested in theoretical and practical applications at the intersection of environment and health. In particular, closer collaboration between these two fields can lead to addressing blind spots in the ecosystem services framework, complementary social-network analysis, the application of resilience heuristics to the understanding of health, and the development of a normative dimension in resilience thinking

    The Unusual Infrared Object HDF-N J123656.3+621322

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    We describe an object in the Hubble Deep Field North with very unusual near-infrared properties. It is readily visible in Hubble Space Telescope NICMOS images at 1.6um and from the ground at 2.2um, but is undetected (with signal-to-noise <~ 2) in very deep WFPC2 and NICMOS data from 0.3 to 1.1um. The f_nu flux density drops by a factor >~ 8.3 (97.7% confidence) from 1.6 to 1.1um. The object is compact but may be slightly resolved in the NICMOS 1.6um image. In a low-resolution, near-infrared spectrogram, we find a possible emission line at 1.643um, but a reobservation at higher spectral resolution failed to confirm the line, leaving its reality in doubt. We consider various hypotheses for the nature of this object. Its colors are unlike those of known galactic stars, except perhaps the most extreme carbon stars or Mira variables with thick circumstellar dust shells. It does not appear to be possible to explain its spectral energy distribution as that of a normal galaxy at any redshift without additional opacity from either dust or intergalactic neutral hydrogen. The colors can be matched by those of a dusty galaxy at z >~ 2, by a maximally old elliptical galaxy at z >~ 3 (perhaps with some additional reddening), or by an object at z >~ 10 whose optical and 1.1um light have been suppressed by the intergalactic medium. Under the latter hypothesis, if the luminosity results from stars and not an AGN, the object would resemble a classical, unobscured protogalaxy, with a star formation rate >~ 100 M_sun/yr. Such UV-bright objects are evidently rare at 2 < z < 12.5, however, with a space density several hundred times lower than that of present-day L* galaxies.Comment: Accepted for publication in the Astrophysical Journal. 27 pages, LaTeX, with 7 figures (8 files); citations & references updated + minor format change

    Active, but not passive cigarette smoking was inversely associated with mammographic density

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    The opposing carcinogenic and antiestrogenic properties of tobacco smoke may explain why epidemiologic studies have not consistently reported positive associations for active smoking and breast cancer risk. A negative relation between mammographic density, a strong breast cancer risk factor, and active smoking would lend support for an antiestrogenic mechanism. We used multivariable linear regression to assess the associations of active smoking and secondhand smoke (SHS) exposure with mammographic density in 799 pre- and early perimenopausal women in the Study of Women’s Health Across the Nation (SWAN). We observed that current active smoking was associated with 7.2% lower mammographic density, compared to never active smoking and no SHS exposure (p = 0.02). Starting to smoke before 18 years of age and having smoked ≄20 cigarettes/day were also associated with statistically significantly lower percent densities. Among nulliparous women having smoked ≄20 cigarettes/day was associated with 23.8% lower density, compared to having smoked ≀9 cigarettes/day (p &lt; 0.001). Our findings support the hypothesis that tobacco smoke exerts an antiestrogenic effect on breast tissue, but counters the known increased risk of breast cancer with smoking prior to first full-term birth. Thus, our data suggest that the antiestrogenic but not the carcinogenic effects of smoking may be reflected by breast density

    La pratique de la transdisciplinarité dans les approches écosystémiques de la santé

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    Les approches Ă©cosystĂ©miques de la santĂ© (AÉS) reconnaissent l’interdĂ©pendance de la santĂ© humaine et animale, de la santĂ© des Ă©cosystĂšmes et de la sociĂ©tĂ©. Dans cet article, nous nous pencherons particuliĂšrement sur la transdisciplinaritĂ©, l’un des six principes associĂ©s Ă  ces approches. L’objectif gĂ©nĂ©ral de cet article est d’explorer comment la transdisciplinaritĂ© est dĂ©finie par des acteurs des AÉS, ainsi que d’identifier des avantages, des opportunitĂ©s, des dĂ©fis et des obstacles qu’elle favorise dans le cadre des AÉS. Des entrevues ont Ă©tĂ© menĂ©es auprĂšs de chercheurs, de praticiens et d’étudiants ayant une expĂ©rience des AÉS et provenant de divers milieux : privĂ© (ONG), universitaire et gouvernemental. Les rĂ©sultats ont montrĂ© que la dĂ©finition de la transdisciplinaritĂ© pour les rĂ©pondants se prĂ©sente sur un continuum entre le paradigme et l’outil de collaboration et que de façon paradoxale, mais non irrĂ©conciliable, la plupart des Ă©lĂ©ments discutĂ©s en tant que dĂ©fis pour certains sont des avantages pour d’autres. Nous concluons sur l’absence de dĂ©finition de la transdisciplinaritĂ© et de savoir-faire communs dans les AÉS ainsi que sur l’intĂ©rĂȘt de poursuivre certaines pistes de rĂ©flexion concernant le partage d’une vision commune de la pratique transdisciplinaire au sein de ces approches, le dĂ©veloppement d’outils facilitant sa pratique et la mise en place de processus d’évaluation des projets

    Functional expression of the plant alternative oxidase affects growth of the yeast i Schizosaccharomyces pombe.

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    We have investigated the extent to which functional expression of the plant alternative oxidase (from Sauromatum guttatum) in Schizosaccharomyces pombe affects yeast growth. When cells are cultured on glycerol, the maximum specific growth rate is decreased from 0.13 to 0.11 h(-1) while growth yield is lowered by 20% (from 1.14 x 10(8) to 9.12 x 10(7) cells ml(-1)). Kinetic studies suggest that the effect on growth is mitochondrial in origin. In isolated mitochondria we found that the alternative oxidase actively competes with the cytochrome pathway for reducing equivalents and contributes up to 24% to the overall respiratory activity. Metabolic control analysis reveals that the alternative oxidase exerts a considerable degree of control (22%) on total electron flux. Furthermore, the negative control exerted by the alternative oxidase on the flux ratio of electrons through the cytochrome and alternative pathways is comparable with the positive control exerted on this flux-ratio by the cytochrome pathway. To our knowledge, this is the first paper to report a phenotypic effect because of plant alternative oxidase expression. We suggest that the effect on growth is the result of high engagement of the non-protonmotive alternative oxidase in yeast respiration that, consequently, lowers the efficiency of energy conservation and hence growth
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