Development of an Instrumentation System for a Laboratory Model Food Product Dryer

To achieve optimal dryer performance, the process parameters required for both the optimization and control of the drying process must be made available via the instrumentation system. A few works have been reported on the development of instrumentation systems for handling drying system parameters. Out of which, some are deficient in the number of drying process parameters that can be handled, while others are unreliable and inaccurate. Therefore, there is the need to develop a microcontroller-based instrumentation system that can monitor, measure, control, display and store the main drying process parameters and sample weight with a high degree of reliability and accuracy. In this study, the sensors were selected based on system specifications and interfaced with the microcontroller. The codes for controlling, logging and displaying of drying parameters were developed and installed on the microcontroller. When tested at steady-state conditions, the system yielded satisfactory results with maximum control and detection errors being 2.0% and 1.8% for the temperature and sample weight, respectively. The developed system can be used for efficient computation of both the dry and wet basis sample moisture content values and also detect the set sample weight. Keywords— Dryer, Drying parameters, Instrumentation system, Moisture content, Sensor

Development and Performance Evaluation of a Manually-Operated Multipurpose Fruit Juice Extractor

A simply and manually-operated multipurpose fruit juice extractor was designed, constructed and its performance was evaluated in terms of juice yield, extraction efficiency, juice content, extraction loss and extraction capacity. The machine has two major parts which are: the extraction chamber and the structural frame. The extraction chamber is made of stainless steel and consists of a turning handle (f24.5 x 400mm), screw rod (f32 x 620 mm), compression plate (f100 mm), perforated inner cylinder (f115 x 180 mm), non-perforated outer cylinder (f120 x 180 mm) and discharge pipe. The structural frame (350 mm x 415 mm x 60 mm) is made of mild steel of U-channel section. The machine basically works on the principle of transmission of compressive force to rupture the juice cells of the fruit for the liberation of juice. Sweet orange, watermelon, red apple, green apple, pineapple, lime, lemon and grape were used for the performance evaluation process. Results obtained showed that pineapple had the highest values of juice yield (68.74%),juice content (66.40%), extraction capacity (92.85 g/min) and extraction efficiency (82.99%) while sweet orange and lime had the lowest extraction loss and extraction capacity of 1.67% and  29.81 (g/min) respectively

Provider Attitudes and Practice Patterns for Direct-Acting Antiviral Therapy for Patients with Hepatocellular Carcinoma

BACKGROUND & AIMS: Direct-acting antivirals (DAAs) are effective against hepatitis C virus and sustained virologic response is associated with reduced incidence of hepatocellular carcinoma (HCC). However, there is controversy over the use of DAAs in patients with active or treated HCC and uncertainty about optimal management of these patients. We aimed to characterize attitudes and practice patterns of hepatology practitioners in the United States regarding the use of DAAs in patients with HCC. METHODS: We conducted a survey of hepatology providers at 47 tertiary care centers in 25 states. Surveys were sent to 476 providers and we received 279 responses (58.6%). RESULTS: Provider beliefs about risk of HCC recurrence after DAA therapy varied: 48% responded that DAAs reduce risk, 36% responded that DAAs do not change risk, and 16% responded that DAAs increase risk of HCC recurrence. However, most providers believed DAAs to be beneficial to and reduce mortality of patients with complete responses to HCC treatment. Accordingly, nearly all providers (94.9%) reported recommending DAA therapy to patients with early-stage HCC who received curative treatment. However, fewer providers recommended DAA therapy for patients with intermediate (72.9%) or advanced (57.5%) HCC undergoing palliative therapies. Timing of DAA initiation varied among providers based on HCC treatment modality: 49.1% of providers reported they would initiate DAA therapy within 3 months of surgical resection whereas 45.9% and 5.0% would delay DAA initiation for 3-12 months and \u3e1 year post-surgery, respectively. For patients undergoing transarterial chemoembolization (TACE), 42.0% of providers would provide DAAs within 3 months of the procedure, 46.7% would delay DAAs until 3-12 months afterward, and 11.3% would delay DAAs more than 1 year after TACE. CONCLUSION: Based on a survey sent to hepatology providers, there is variation in provider attitudes and practice patterns regarding use and timing of DAAs for patients with HCC. Further studies are needed to characterize the risks and benefits of DAA therapy in this patient population