4 research outputs found
Antimicrobial activity of the ethanol extract of the aerial parts of sida acuta burm.f. (malvaceae)
Purpose: The antimicrobial activity of the 90 % ethanol extract of the
aerial parts of sida acuta Burm. F. (Malvaceae) was investigated in
other to verify its claimed ethno medicinal use in the treatment of
microbial infections. Method: The antimicrobial activity of the extract
was tested against standard strains and clinical isolates of some
aerobic bacteria and a fungus using the Agar well diffusion method.
Commercial antibiotics were used as positive reference standards to
determine the sensitivity of the strains. Results: The extracts showed
significant inhibitory activity against standard strains and clinical
isolates of Staphylococcus aureus, clinical isolates of Bacillus
subtilis and Streptococcus faecalis. The MIC values obtained using the
Agar-dilution test ranged from 5.0 mg/ml. -10.0 mg/ml. Neither the
concentrated extract nor its dilutions inhibited Escherichia coli ,
Klebsiella pneumonia , Pseudomonas aeruginosa and Candida albicans
Conclusion: The results demonstrate that the crude extract of the
aerial parts of Sida acuta has a narrow spectrum of activity and
suggest that it may be useful in the treatment of infections caused by
Gram positive aerobic bacteria