41 research outputs found
Rational Clinical Dose Selection of Adeno‐Associated Virus‐Mediated Gene Therapy Based on Allometric Principles
No full textIntegration of Physiologically‐Based Pharmacokinetic Modeling into Early Clinical Development: An Investigation of the Pharmacokinetic Nonlinearity
No full text
Quantitative prediction of drug interactions. Use of codeine depletion time profiles in rat microsomes and hepatocytes.
No full textQuantitiative prediction of drug interactions. Inhibition of morphine formation from codeine (CYP2D6)and substrate binding/uptake in rat microsomes and hepatocytes.
No full textEffects of Statins on the Recovery of Olfactory Function in a 3-Methylindole–Induced Anosmia Mouse Model
No full textNo Clinically Relevant Interactions of St. John's Wort Extract Ze 117 Low in Hyperforin With Cytochrome P450 Enzymes and P‐glycoprotein
No full text
Evaluation of Various Static In Vitro–In Vivo Extrapolation Models for Risk Assessment of the CYP3A Inhibition Potential of an Investigational Drug
No full text
