7 research outputs found
Developing personas & use cases with user survey data: A study on the millennials’ media usage
The aim of the study is to investigate the characteristics of millennials on the usage of media (music, photo/video) and media-related devices. An online survey was conducted on 360 millennials. Based on the results, we developed representative use cases to be used in experience design projects based on the actual media usage data collected. We also classified the millennials into four specific groups by applying statistical cluster analysis techniques. The characteristics of each group were further identified. The results of this study will help designers to develop products and services that meet the needs of their target consumers.11Nssciscopu
The Role of IL-7 and IL-7R in Cancer Pathophysiology and Immunotherapy
Interleukin-7 (IL-7) is a multipotent cytokine that maintains the homeostasis of the immune system. IL-7 plays a vital role in T-cell development, proliferation, and differentiation, as well as in B cell maturation through the activation of the IL-7 receptor (IL-7R). IL-7 is closely associated with tumor development and has been used in cancer clinical research and therapy. In this review, we first summarize the roles of IL-7 and IL-7Rα and their downstream signaling pathways in immunity and cancer. Furthermore, we summarize and discuss the recent advances in the use of IL-7 and IL-7Rα as cancer immunotherapy tools and highlight their potential for therapeutic applications. This review will help in the development of cancer immunotherapy regimens based on IL-7 and IL-7Rα, and will also advance their exploitation as more effective and safe immunotherapy tools