8 research outputs found
Combined anatomical and functional diagnostic work-up of patients with suspected coronary artery disease using cardiac computed tomography and magnetic resonance imaging
Effects of the pollution by petroleum on the tracheids along the stem of Podocarpus lambertii Klotzsch ex Endl., Podocarpaceae
DEFINING THE NORMAL LIMITS OF MYOCARDIAL BLOOD FLOW IN PATIENTS EVALUATED FOR CORONARY ARTERY DISEASE BY MEANS OF [15O] POSITRON EMISSION TOMOGRAPHY: IMPACT OF GENDER AND RISK PROFILE
A Role For The Prefrontal Cortex In Heroin-Seeking After Forced Abstinence By Adult Male Rats But Not Adolescents
Opiate versus psychostimulant addiction: the differences do matter
The publication of the psychomotor stimulant theory of addiction in 1987 and the finding that addictive drugs increase dopamine concentrations in the rat mesolimbic system in 1988 have led to a predominance of psychobiological theories that consider addiction to opiates and addiction to psychostimulants as essentially identical phenomena. Indeed, current theories of addiction - hedonic allostasis, incentive sensitization, aberrant learning and frontostriatal dysfunction - all argue for a unitary account of drug addiction. This view is challenged by behavioural, cognitive and neurobiological findings in laboratory animals and humans. Here, we argue that opiate addiction and psychostimulant addiction are behaviourally and neurobiologically distinct and that the differences have important implications for addiction treatment, addiction theories and future research