Assessment of antimicrobial activity of polyazolidinammonium modified by iodine hydrate ions depending on its physical and chemical characteristics.

Aim: to study antimicrobial activity of variants of polymeric compound polyazolidinammonium modified by iodine hydrate-ions (PAAG-M), depending on the polymeric chain length and concentration of the iodine hydrate-ions against standard strains of gram-positive and gram-negative bacteria as well as microscopic fungi. Materials and methods. Minimum inhibitory concentrations of all variants of the polymeric compound for tested microbial strains have been determined by using serial dilution method. Results. High sensitivity of Eschehchia coli 113-13 and Pseudomonas aeruginosa ATCC 27853 was shown to the variants of PAAG-M with molecular weight <100 and 100-200 kD. Staphylococcus aureus 209 P was more sensitive to the variants with molecular weight 200-350 and 400-500 kD. Direct relation of sensitivity was demonstrated for all microbial strains on the increase of iodine hydrate-ions concentration in the polymeric compound. Standard strain Candida albicans 13108 was sensitive to variants of the polymer with maximum iodine hydrate-ions concentration. Conclusion. The received results allow to carry out a choice of the most effective chemotherapeutic antimicrobic preparations depending on biological properties of the activator of infectious process

Child health status — the future of the country (part 2)

The article deals with the problems of increasing the incidence and prevalence of childhood diseases during 1994–2016 against the background of a global reduction in the staffing of children’s specialists by 1.7 times, with an extremely inadequate supply of the regions of the South-East, Donetsk and Luhansk regions. All of this has a negative impact on the proper medical care of the child population, including the detection of childhood diseases. The authors substantiate the need to restore the personnel and material-technical potential of the pediatric service, the development of modern diagnostic and treatment technologies, the preservation of immunization and the prevention of disability of common childhood diseases that is an important component of the national health care and safety system of the country as a whole