441 research outputs found
This thing called communitarianism: A critical review of Matolino's Personhood in African Philosophy
The subject of personal identity has received substantial treatment in contemporary
African philosophy. Importantly, the dominant approach to personal identity is
communitarian. Bernard Matolino's new book Personhood in African Philosophy
enters into this discussion by way of contesting some of the assumptions underlying
communitarian approaches. His own critical assessment leads him to what I believe
is an unprecedented objection in the literature; the conclusion that communitarian
philosophers are involved in a category mistake when framing the question and
articulating the notion of personhood. I intend to present a brief summary of the
chapters of the book and reflect on some of the main philosophical issues that the
book provokes, noting what I take to be refreshing insights that Matolino brings to
the discussion while also engaging critically with the ones I find most contentious.
In particular, I briefly assess Matolino's implicit suggestion that an Akan inspired
quasi-physicalist account of mind avoids the mind-body interaction problem; I
object to the category mistake charge on behalf of communitarians; and lastly, I raise
questions about, and propose ways Matolino can refine, his proposal concerning
a new way of thinking about personhood, which goes under the rubric of Limited
Communitarianism.IS
On the alpha activity of natural tungsten isotopes
The indication for the alpha decay of 180-W with a half-life
T1/2=1.1+0.8-0.4(stat)+-0.3(syst)x10^18 yr has been observed for the first time
with the help of the super-low background 116-CdWO_4 crystal scintillators. In
conservative approach the lower limit on half-life of 180-W has been
established as T1/2>0.7x10^18 yr at 90% C.L. Besides, new T1/2 bounds were set
for alpha decay of 182-W, 183-W, 184-W and 186-W at the level of 10^20 yr.Comment: 16 pages, 8 figures, accepted in Phys. Rev.
A Randomized, Placebo-controlled Trial of Preemptive Antifungal Therapy for the Prevention of Invasive Candidiasis Following Gastrointestinal Surgery for Intra-abdominal Infections.
BACKGROUND: Patients undergoing emergency gastrointestinal surgery for intra-abdominal infection are at risk of invasive candidiasis (IC) and candidates for preemptive antifungal therapy.
METHODS: This exploratory, randomized, double-blind, placebo-controlled trial assessed a preemptive antifungal approach with micafungin (100 mg/d) in intensive care unit patients requiring surgery for intra-abdominal infection. Coprimary efficacy variables were the incidence of IC and the time from baseline to first IC in the full analysis set; an independent data review board confirmed IC. An exploratory biomarker analysis was performed using logistic regression.
RESULTS: The full analysis set comprised 124 placebo- and 117 micafungin-treated patients. The incidence of IC was 8.9% for placebo and 11.1% for micafungin (difference, 2.24%; [95% confidence interval, -5.52 to 10.20]). There was no difference between the arms in median time to IC. The estimated odds ratio showed that patients with a positive (1,3)-β-d-glucan (ßDG) result were 3.66 (95% confidence interval, 1.01-13.29) times more likely to have confirmed IC than those with a negative result.
CONCLUSIONS: This study was unable to provide evidence that preemptive administration of an echinocandin was effective in preventing IC in high-risk surgical intensive care unit patients with intra-abdominal infections. This may have been because the drug was administered too late to prevent IC coupled with an overall low number of IC events. It does provide some support for using ßDG to identify patients at high risk of IC.
CLINICAL TRIALS REGISTRATION: NCT01122368
The high-pressure phase of boron, {\gamma}-B28: disputes and conclusions of 5 years after discovery
{\gamma}-B28 is a recently established high-pressure phase of boron. Its
structure consists of icosahedral B12 clusters and B2 dumbbells in a NaCl-type
arrangement (B2){\delta}+(B12){\delta}- and displays a significant charge
transfer {\delta}~0.5- 0.6. The discovery of this phase proved essential for
the understanding and construction of the phase diagram of boron. {\gamma}-B28
was first experimentally obtained as a pure boron allotrope in early 2004 and
its structure was discovered in 2006. This paper reviews recent results and in
particular deals with the contentious issues related to the equation of state,
hardness, putative isostructural phase transformation at ~40 GPa, and debates
on the nature of chemical bonding in this phase. Our analysis confirms that (a)
calculations based on density functional theory give an accurate description of
its equation of state, (b) the reported isostructural phase transformation in
{\gamma}-B28 is an artifact rather than a fact, (c) the best estimate of
hardness of this phase is 50 GPa, (d) chemical bonding in this phase has a
significant degree of ionicity. Apart from presenting an overview of previous
results within a consistent view grounded in experiment, thermodynamics and
quantum mechanics, we present new results on Bader charges in {\gamma}-B28
using different levels of quantum-mechanical theory (GGA, exact exchange, and
HSE06 hybrid functional), and show that the earlier conclusion about
significant degree of partial ionicity in this phase is very robust
Strongly Hyperbolic Extensions of the ADM Hamiltonian
The ADM Hamiltonian formulation of general relativity with prescribed lapse
and shift is a weakly hyperbolic system of partial differential equations. In
general weakly hyperbolic systems are not mathematically well posed. For well
posedness, the theory should be reformulated so that the complete system,
evolution equations plus gauge conditions, is (at least) strongly hyperbolic.
Traditionally, reformulation has been carried out at the level of equations of
motion. This typically destroys the variational and Hamiltonian structures of
the theory. Here I show that one can extend the ADM formalism to (i)
incorporate the gauge conditions as dynamical equations and (ii) affect the
hyperbolicity of the complete system, all while maintaining a Hamiltonian
description. The extended ADM formulation is used to obtain a strongly
hyperbolic Hamiltonian description of Einstein's theory that is generally
covariant under spatial diffeomorphisms and time reparametrizations, and has
physical characteristics. The extended Hamiltonian formulation with 1+log
slicing and gamma--driver shift conditions is weakly hyperbolic.Comment: This version contains minor corrections and clarifications. The
format has been changed to conform with IOP styl
Active Brownian Particles. From Individual to Collective Stochastic Dynamics
We review theoretical models of individual motility as well as collective
dynamics and pattern formation of active particles. We focus on simple models
of active dynamics with a particular emphasis on nonlinear and stochastic
dynamics of such self-propelled entities in the framework of statistical
mechanics. Examples of such active units in complex physico-chemical and
biological systems are chemically powered nano-rods, localized patterns in
reaction-diffusion system, motile cells or macroscopic animals. Based on the
description of individual motion of point-like active particles by stochastic
differential equations, we discuss different velocity-dependent friction
functions, the impact of various types of fluctuations and calculate
characteristic observables such as stationary velocity distributions or
diffusion coefficients. Finally, we consider not only the free and confined
individual active dynamics but also different types of interaction between
active particles. The resulting collective dynamical behavior of large
assemblies and aggregates of active units is discussed and an overview over
some recent results on spatiotemporal pattern formation in such systems is
given.Comment: 161 pages, Review, Eur Phys J Special-Topics, accepte
The COMPASS Experiment at CERN
The COMPASS experiment makes use of the CERN SPS high-intensitymuon and
hadron beams for the investigation of the nucleon spin structure and the
spectroscopy of hadrons. One or more outgoing particles are detected in
coincidence with the incoming muon or hadron. A large polarized target inside a
superconducting solenoid is used for the measurements with the muon beam.
Outgoing particles are detected by a two-stage, large angle and large momentum
range spectrometer. The setup is built using several types of tracking
detectors, according to the expected incident rate, required space resolution
and the solid angle to be covered. Particle identification is achieved using a
RICH counter and both hadron and electromagnetic calorimeters. The setup has
been successfully operated from 2002 onwards using a muon beam. Data with a
hadron beam were also collected in 2004. This article describes the main
features and performances of the spectrometer in 2004; a short summary of the
2006 upgrade is also given.Comment: 84 papes, 74 figure
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