9 research outputs found

    The effect of amixin and agmatine on cytochrome c release from isolated mitochondria

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    Mitochondrial nicotinic acetylcholine receptors (nAChRs) control permeability transition pore formation and cytochrome c release in the presence of apoptogenic factors. This study demonstrates that pharmacological agents amixin and agmatine affect mitochondrial nAChR functioning: they slightly suppress cytochrome c release from mouse brain and liver mitochondria stimulated with apoptogenic dose of 小邪2+ and prevent the effect of 伪7 nAChR agonist PNU282987. We conclude that mitochondria may be one of therapeutic targets of amixin and agmatine

    The role of nicotinic cholinergic neurotransmission in delusional thinking

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    Lie groups and homogeneous spaces

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