66 research outputs found
PROBLEMS OF ENVIRONMENTAL TERMINOLOGY TRANSLATION BY STUDENTS IN THE PROCESS OF STUDYING FOREIGN LANGUAGE IN HIGHER EDUCATIONAL INSTITUTION
The analysis of the problem of environmental terminology translation by students in the process of studying foreign language in higher educational institutions is given. On the basis of scientific research by prominent scientists, the essence of the concepts of "term" and "ecological term" is analyzed. The main attention is devoted to the study of the causes arising during the translation of the environmental sphere terms. Some aspects of simplifying the process of terms translation are considered. Further research in this area is possible in order to find sources of English and Ukrainian environmental terminology origin.Key words: term, ecological term, terminology system, ecology, term definition, environmental protection, simple term, derivative term.Кулько В. А., Горбаньова О. О., кандидат філологічних наук Бірюкова Д. В. Проблеми перекладу екологічної термінології студентами в процесі вивчення іноземної мови у ВНЗ / Університет митної справи та фінансів, Україна, ДніпроВ даній статті надано аналіз проблеми перекладу екологічної термінології студентами в процесі вивчення іноземної мови у ВНЗ. На основі наукових досліджень видатних вчених проаналізовано сутність понять «термін» та «екологічний термін». Основну увагу приділено дослідженню причин, які виникають у студентів під час перекладу термінів екологічної сфери. Розглянуто деякі аспекти щодо спрощення процесу перекладу термінів. Подальші дослідження в цій області можливі з метою пошуку джерел походження англійської та української екологічної термінології.Ключові слова: термін, екологічний термін, термінологічна система, екологія, дефініції терміна, охорона навколишнього середовища, простий термін, похідний термін
IMPROVING STUDENTS` READING SKILLS AS INTEGRAL PART OF PROFESSIONAL DEVELOPMENT
The purpose of this study is to analyze the effectiveness of obtaining reading skills by students in the process of teaching а foreign language at a higher educational institution. The principal result of our research is the analysis of the efficiency of using teaching techniques on acquiring reading competence. The major conclusions estimate the significance of gaining reading competence in learning process for professional development. Keywords: reading skills, teaching foreign languages, text comprehension, guesses, semantic synthesis, semantic processing.Горбаньова О. О., Кулько В. В., кандидат філологічних наук, доцент, Бірюкова Д. В. Розвиток навичок читання студентів як невід’ємна частина професійного росту / Університет митної справи та фінансів Дніпро, Україна Метою даного дослідження є аналіз ефективності одержання навичок читання студентами у процесі викладання іноземної мови у вищому навчальному закладі. Основним результатом нашого дослідження є аналіз ефективності використання методики викладання для досягнення компетентності в читанні. Основні висновки оцінюють важливість набуття компетентності в читанні для професійного розвитку. Ключові слова: навички читання, викладання іноземних мов, розуміння тексту, здогади, семантичний синтез, семантична обробка.Горбанева О. А., Кулько В. В., кандидат филологических наук, Бирюкова Д. В. Развитие навыков чтения студентов как неотъемлемая часть профессионального роста / Университет таможенного дела и финансов, Днепр, УкраинаЦель данного исследования - проанализировать эффективность получения студентами навыков чтения в процессе обучения иностранному языку в вузе. Основным результатом нашего исследования является анализ эффективности использования методик обучения при приобретении навыков чтения. Основные выводы оценивают важность получения навыков чтения в процессе обучения для профессионального развития. Ключевые слова: навыки чтения, обучение иностранным языкам, понимание текста, догадки, семантический синтез, семантическая обработка
Chemiluminescence activity of neutrophil granulocytes under the influence of magnetic nanoparticles of ferrihydrite (<i>in vitro</i>)
The article presents the results of studying and evaluating the impact of magnetic nanoparticles of ferrihydrite on neutrophil granulocytes in human blood (in vitro) in order to determine their bio compatibility and eco toxicity. The subject soft here search were blood neutrophil granulocytes of 29 conditionally-healthy donors of blood, as well as magnetic nanoparticles of ferrihydrite (NP), the preparation dose in minimum concentration reached 25 mg, in maximum concentration it reached 50 mg per 106 cells/ml. We implemented the sol of magnetic NP, obtained by biogenic synthesis in International Scientific Centre for Studying Extreme States of an Organism. Functional activity of blood neutrophil granulocytes has been determined by luminol-dependent chemiluminescence. Magnetic NP were introduced into pilot samples straight before chemiluminescent analysis, and also after the incubation with in 30 minutes under 37 °С entigrade. As a result of thee stimation of the early response of neutrophil granulocytes to the influence of minimum concentration of magnetic NP in vitro we found statistically true decrease of the intensity (1.6 times), the area under the curve (2.1 times) in zymosan-induced chemiluminescent response, the activation index (2.3 times). When evaluating the late response of neutrophil granulocytes to the influence of maximum concentration of magnetic NP in vitro we have found statistically true lowering of the time of reaching the peak (10 times) of spontaneous chemiluminescence. More over we marked consider able lowering of maximum intensity 6 times and the reduction of the area under the curve of zymosan-induced chemiluminescence 5.6 times under the influence of magnetic NP under the lowering of activation index 3.7 times. The authors determined that magnetic NP were intensively decreasing the functional activity of neutrophil granulocytes. The intensity of the impact is higher under the preliminary incubation of the cells with magnetic NP. At the same time, short effect of magnetic NP to neutrophil granulocytes can be a modulating one and depends on the initial level of cell reactivity. We revealed that magnetic NP influence concerns only activated cells
Effectiveness and safety of therapeutics used for treatment of experimental or spontaneous <i>Mycoplasma</i> infections
Mycoplasmoses of cattle and small ruminants, pigs and poultry are widely spread and the infection process is frequently associated with other diseases. Mycoplasma spp. cause inflammatory respiratory diseases, diseases of joints and meninges, keratoconjunctivitis, mastitis and endometritis, abortion and stillbirths. Etiotropic therapy of mycoplasmal infections consists in prescribing antibiotics: enrofloxacin, difloxacin, oxytetracycline, chlortetracycline, doxycycline, tylosin, tilmicosin, tylvalosin, tiamulin, florfenicol, lincomycin, spectinomycin, tulathromycin. The results of studies described in different publications show high sensitivity of Mycoplasma synoviae and Mycoplasma gallisepticum to tetracyclines, tiamulin and tylvalosin. Isolates with increased resistance to tilmicosin are also resistant to tylosin and lincomycin. Treatment of respiratory infections in lambs, the main causative agents of which are Mannheimia haemolytica and Mycoplasma, has been successful with the use of fluoroquinolones, tilmicosin, tulathromycin, chlortetracycline, enrofloxacin, doxycycline, and oxytetracycline. Isolates of Mycoplasma bovis are largely sensitive to oxytetracycline, florfenicol and tulathromycin. Enrofloxacin has a less pronounced therapeutic effect. Tilmicosin and oxytetracycline are effective in the treatment of respiratory diseases of young cattle, associated with Mycoplasma spp. Tulathromycin and tilmicosin have a significant therapeutic effect in the treatment of pneumonia in weaned piglets experimentally infected with Mycoplasma hyopneumoniae. Multiple (course) use of enrofloxacin significantly increases the therapeutic effect. Tilmicosin is effective in the control of other bacterial infections of pigs (pasteurellosis, streptococcosis, hemophilic polyserositis, infectious atrophic rhinitis).The general prophylaxis of mycoplasmal infections is to comply with veterinary and sanitary standards and to implement quarantine measures in the infection outbreak
Analysis of thermal work of boiler DKVR-20-13
The paper presents the results of a study of the thermal efficiency of the boiler DKVR-20-13. Based on the results of the study, the efficiency of the boiler is determined at various loads. There are given recommendations for increasing thermal efficiency.В работе изложены результаты исследования тепловой эффективности котла ДКВР-20-13. По результатам исследования определён КПД котла при различных нагрузках. Даны рекомендации по увеличению тепловой эффективности
Chronic endometritis and infertility — in vitro fertilization outcomes: systematic review and meta-analysis
Background. The relevance of the problem is related to the high prevalence of chronic endometritis (CE); its role in female infertility, implantation failures during assisted reproductive technology procedures, and recurrent miscarriage; as well as the lack of a unified strategy in the diagnosis and treatment of this pathology. The present systematic review with a meta-analysis focuses on evaluating the impact of CE and its therapy on the outcome of in vitro fertilization. In addition, the effect of CE of various severity on the outcomes of assisted reproductive technologies is analyzed. Objective. To analyze the effect of CE of varying severity and its treatment on the outcomes of in vitro fertilization. Methods. Using PubMed, Medline, Scopus, Embase, ELibrary, Cochrane Central Register of Controlled Trials (CENTRAL), WHO International Clinical Trials Registry, and Russian Science Citation Index, a systematic search was conducted for articles published over the past 12 years that met the following criteria: randomized controlled trial examining the effect of CE of varying severity on fertility and ways to treat it. The following indicators were calculated: ongoing pregnancy/live birth, clinical pregnancy, and miscarriage rates. A total of 4145 patients (from ten studies) were included. A meta-analysis was performed using Stata 11.0 software (The Cochrane Collaboration, Oxford, UK). The heterogeneity was considered low at I2 <30%, moderate at 30–50%, and high at >50%. Results. Women with CE exhibited lower ongoing pregnancy/live birth (OR 1.97; p = 0.02) and clinical pregnancy rates (OR 2.28; p = 0.002) as compared to women without it. CE treatment increased the ongoing pregnancy/live birth (OR 5.33; p < 0.0001) and clinical pregnancy rates (OR 3.64; p = 0.0001). In vitro fertilization outcomes were comparable in women treated for CE and women without CE (ongoing pregnancy/live birth rate, clinical pregnancy rate, and miscarriage rate: p = ns). Women with severe CE exhibited lower ongoing pregnancy/live birth (OR 0.43; p = 0.003) and clinical pregnancy rates (OR 0.40; p = 0.0007). Mild CE showed no significant effect on in vitro fertilization outcomes (ongoing pregnancy/ live birth rate, clinical pregnancy rate, and miscarriage rate: p = ns). Conclusion. The conducted meta-analysis showed that CE significantly reduces the ongoing pregnancy/live birth and clinical pregnancy rates in infertile women undergoing in vitro fertilization. Noteworthy is that antimicrobial therapy in such patients improves the results of assisted reproductive technologies, which are comparable to those of patients without CE. The negative impact of this pathology on the implantation capacity of the endometrium is most often observed in the severe form, while its mild form has virtually no effect on the in vitro fertilization outcome
CLINICAL EXPERIENCE OF POST-STROKE REHABILITATION WITH THE USE OF HAND EXOSKELETON CONTROLLED BY BRAIN-COMPUTER INTERFACE
Aim - to evaluate the efficiency of the motor recovery rehabilitation procedure with the use of hand exoskeleton controlled by the brain-computer interface (BCI). Materials and methods. 60 post-stroke patients participated in the study. 46 patients had ischemic stroke and 14 had hemorrhagic stroke. 42 patients of the main experimental group were trained in kinesthetic motor imagery using hand exoskeleton controlled by BCI, 18 patients of the control group carried out the imitating procedure. Exoskeleton - BCI system consists of encephalograph NVX52 («Medical Computer Systems», Russia), personal computer and hand exoskeleton («Android Technique», Russia). Motor functions were estimated by neurological scales ARAT and Fugl-Meyer. Results were statistically analyzed by Mann-Whitney, Wilcoxon and x2 tests, Spearman's correlation and RM-ANOVA using Statsoft Statistica v. 6.0. Results. It is shown that post-stroke patients are able to control BCI with the same efficiency as healthy subjects, regardless of the duration, severity and localization of the disease. Ten days of BCI training significantly improved patients’ motor functions according to neurological scales ARAT and Fugl-Meyer. Improvement was mainly provided by the small movements of the hand. According to several sections of neurological scales, improvement in the main group is significantly higher than in the control group. However, according to general scores, statistically significant difference between two groups was not observed. Conclusion. It is shown that the rehabilitation procedure using hand exsoskeleton controlled by BCI significantly improves motor functions of the paretic arm regardless of the duration, severity and localization of the disease. Increase of the training duration enhances the rehabilitation efficiency
Электрофоретическая подвижность эритроцитов у больных с тяжелыми формами интоксикации
Objective: to study the diagnostic and prognostic value of changes in red blood cell electrophoretic mobility (RBCEM) in patients with infectious and noninfectious forms of intoxication.Materials and methods. A cytoferometer (Opton) was used to determine RBCEM; venous blood samples taken on heparin were studied. Thirty patients with peritonitis (infectious intoxication) and 22 patients with a pancreatic tumor and mechanical jaundice (noninfectious intoxication) were examined. All the patients received standard therapy for this disease. Eight out of 30 patients died on days 3—10 postoperatively.Results. On postoperative days 1—2, the values of RBCEM were outside the lower normal range in 90% of the patients with peritonitis (p<0.01). At the same time the patients with a good outcome of the disease differed from those who subsequently died (p<0.05), but they did not differ in the severity of the disease (APACHE II scale) and the results of laboratory and clinical blood tests. On days 7—14 versus days 1—2 after surgery, the survivors, unlike the deceased, showed an increase in RBCEM (p<0.05) and a reduction in disease severity by the APACHE II scale (p<0.05). On admission, in 95% of patients with pancreatic tumor, the values of RBCEM were beyond the lower normal range (p<0.01). Seven-day disintoxicant therapy caused a rise in this index.Conclusion. Intoxication with infectious and noninfectious agents leads to lower RBCEM. In patients with general peritonitis, the values of this index and its changes are of diagnostic and prognostic value in evaluating the severity and outcome of the disease and the efficiency of performed therapeutic measures. Цель. Изучение диагностической и прогностической значимости изменений электрофоретической подвижности эритроцитов (ЭФПЭ) у больных с инфекционной и неинфекционной формами интоксикации организма.Материалы и методы. Для определения ЭФПЭ был использован цитоферометр фирмы «Opton», материалом для исследования служила венозная кровь, взятая на гепарине. Обследование проведено у 30 больных с перитонитом (инфекционная форма интоксикации) и у 22 больных опухолью поджелудочной железы с механической желтухой (неинфекционная форма интоксикации). Всем больным проводили стандартизированную терапию для данного заболевания. Из 30 больных перитонитом 8 умерли на 3—10 сутки после операции.Результаты. На 1—2-е сутки после операции у 90% больных с перитонитом величины ЭФПЭ находились за пределами нижней границы нормы (р<0,01). При этом больные с благоприятным исходом заболевания отличались от впоследствии умерших более высокими значениями этого показателя (р<0,05), но не различались по тяжести состояния (шкала АРАСНЕ II), результатам лабораторно-клинического анализа крови. На 7—14-е сутки после операции у выживших больных, в отличие от умерших, наблюдалось увеличение ЭФПЭ (р<0,05) и уменьшение тяжести их состояния по шкале АРАСНЕ II (р<0,05) по сравнению с 1—2 сутками послеоперационного периода. При поступлении в стационар у 95% больных с опухолью поджелудочной железы величины ЭФПЭ были меньше нижней границы нормы (р<0,01). Проведение дезинтоксикационной терапии в течение 7 суток сопровождалось увеличением значений этого показателя.Заключение. Интоксикация организма инфекционными и неинфекционными агентами приводит к снижению ЭФПЭ. У больных с разлитым перитонитом значения этого показателя и его динамика имеют диагностическую и прогностическую значимость для оценки тяжести и исхода заболевания, эффективности проводимых лечебных мероприятий.
Evaluation of the effectiveness of age macular degeneration treatment
We examined 176 patients with an established diagnosis of age-related macular degeneration 'dry* form in the early and intermediate stages. The average age - 71,2 + 2,6, the average duration of the disease from the time of diagnosis of the disease 1,9 ± 1,3 years. All patients were divided into two groups: primary - 90 people and a comparison group of 86 people. The study group consisted of patients who underwent neyroprotektional vasodilator therapy: 5 mg Retinalamin subconjunctival injection number 10 and intramuscular injections of nicotinic acid 2,0 № 10. In the comparison group performed neuroprotective and vasodilator therapy in combination simpatocorrection number 10. The result has been found most effective therapeutic strategy: simpatocorrection in combination with the following regimen: 5 mg subconjunctival injection Retinalamin number 10, and intramuscular injection of nicotinic acid, 2.0 N° 10.Нами обследовано 176 больных с установленным диагнозом возрастной макулярной дегенерации «сухая» форма в ранней и промежуточной стадиях. Средний возраст-71,2 + 2,6, средняя продолжительность заболевания от момента диагностики заболевания 1,9+1,3 года. Все пациенты были разделены на две группы: основную - 90 человек и группу сравнения 86 человек. В основную группу вошли пациенты, которым была проведена нейропротекторнаяи сосудорасширяющая терапия: Ретиналамин 5 мг субконъюнктивально №10 и внутримышечные инъекции никотиновой кислоты 2,0 №10. В группе сравнения проводилась нейропротекторная и сосудорасширяющая терапия в сочетании симпатокоррекцией №10. В результате была выявлена наиболее эффективная терапевтическая стратегия, а именно, сочетание симпатокоррекции со следующей схемой лечения: Ретиналамин 5 мг субконъюнктивально № 10, внутримышечные инъекции никотиновой кислоты 2.0 №10
Investigation of oncolytic potential of vaccine strains of yellow fever and tick-borne encephalitis viruses against glioblastoma and pancreatic carcinoma cell lines
Introduction. Flaviviruses, possessing natural neurotropicity could be used in glioblastoma therapy using attenuated strains or as a delivery system for antitumor agents in an inactivated form.
Objective. To investigate the sensitivity of glioblastoma and pancreatic carcinoma cell lines to vaccine strains of yellow fever and tick-borne encephalitis viruses.
Materials and methods. Cell lines: glioblastoma GL-6, T98G, LN-229, pancreatic carcinoma MIA RaCa-2 and human pancreatic ductal carcinoma PANC-1. Viral strains: 17D yellow fever virus (YF), Sofjin tick-borne encephalitis virus (TBEV). Virus concentration were determined by plaque assay and quantitative PCR. Determination of cell sensitivity to viruses by MTT assay.
Results. 17D YF was effective only against pancreatic carcinoma tumor cells MIA Paca-2 and had a limited effect against PANC-1. In glioblastoma cell lines (LN229, GL6, T98G), virus had no oncolytic effect and the viral RNA concentration fell in the culture medium. Sofjin TBEV showed CPE50 against MIA Paca-2 and a very limited cytotoxic effect against PANC-1. However, it had no oncolytic effect against glioblastoma cell lines (LN229, T98G and GL6), although virus reproduction continued in these cultures. For the GL6 glioblastoma cell line, the viral RNA concentration at the level with the infection dose was determined within 13 days, despite medium replacement, while in the case of the LN229 cell line, the virus concentration increased from 1 × 109 to 1 × 1010 copies/ml.
Conclusion. Tumor behavior in organism is more complex and is determined by different microenvironmental factors and immune status. In the future, it is advisable to continue studying the antitumor oncolytic and immunomodulatory effects of viral strains 17D YF and Sofjin TBEV using in vivo models
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