9 research outputs found
Evaluation of chromosomal instability in somatic cells of farmed foxes
The micronucleus
(MN) test is a common tool used to evaluate cellular genetic instability at
the chromosomal level. It determines the effect of physical, chemical and
environmental factors on DNA, and thus the body's individual resistance to
harmful substances. The karyotypes of blue and silver foxes and their
interspecific hybrids are characterized by morphological and structural
variation. This variation is partly attributable to the presence of
chromosomal polymorphism, which may significantly influence the stability of
genetic material in the cells of these species. The objective of the study
was to evaluate genetic material stability in selected Canidae species. To
this end, analyses using the MN test were performed. Binucleated cells (BNCs)
were analysed in microscopic preparations, and the number of micronuclei was
determined within these cells. For the proportions of both MN and BNCs,
highly significant differences were observed between the fox species. The
interspecific hybrids differed from the other fox species in MN percentage.
The lowest average was noted in blue foxes (3.33) and the highest in
interspecific hybrids (15.21).</p