Peculiarities of the induction immunosuppressive therapy in renal transplantation

Peculiarities of the induction immunosuppressive therapy in renal transplantatio

Efficacy of the staged endoscopic ligature of the varicose veins in children, suffering portal hypertension

Objective. To estimate the efficacy of first procedure of endoscopic ligature for the varicose esophageal veins in children, suffering portal hypertension in accordance to data of endoscopic examination. Materials and methods. Endoscopic ligature of the varicose esophageal veins was performed in 24 patients, suffering portal hypertension, aiming at prophylaxis of hemorrhage from the varicose veins. Results. Reduction of the varicose veins degree after first ligature procedure was observed in 14 (58.33%) children, eradication of the varicose veins - in 5 (20.83%) of them. In 1 (4.17%) patient a complication (hemorrhage) have occurred in a moment of a ligature application. In 2 (8.33%) patients a hemorrhage from the varicose veins of stomach have occurred. Conclusion. Endoscopic ligature constitutes a secure and effective prophylactic method for hemorrhage from the esophageal varicose in children, suffering portal hypertension, and permits to control the varicose degree on stages of the portal hypertension treatment. Even after first procedure of endoscopic ligature the esophageal varicose degree have had reduced at average (p < 0.05). After endoscopic ligature the hemorrhage occurrence risk have reduced: p=0.05, and the risks ratio constitutes 0.14 (95% CI 0.04-0.56)