Comparison of quality of life in patients with primary postoperative and autoimmune hypothyreosis

Background. Achieving a high level of quality of life is one of the priorities in the treatment of chronic diseases. Focusing on the quality of life, it is possible to optimally adjust the treatment plan for patients, influencing the link that suffers most in this pathology. Hypothyroidism is mainly formed as a result of surgery on the thyroid gland, or autoimmune thyroiditis, and at the same time is one of the most common endocrine diseases, is of great social importance due to the potentially adverse effect on most organs and systems, resulting in a decrease in quality of life.The aim. To analyze the impact of primary hypothyroidism (postoperative hypothyroidism and autoimmune thyroiditis) on the quality of life of patients.Materials and methods. During the study, a clinical, laboratory and psychological study of 78 women with uncompensated primary hypothyroidism was carried out: 40 women aged 32–76 years with postoperative hypothyroidism (main group) and 38 women aged 36–60 years with autoimmune thyroiditis (comparison group). The quality of life was judged by the indicators of the MOS SF-36 questionnaire.Conclusion. In the examined patients with primary hypothyroidism, an association between an increase in TSH levels and a decrease in all indicators of the quality of life was revealed. First, indicators of physical functioning, general health, role and emotional functioning worsened. The dependence of indicators on the MOS SF-36 scales with the age of patients, the duration of hypothyroidism, and the level of TSH was revealed. The quality of life in patients with postoperative hypothyroidism was significantly reduced compared to patients who had hypothyroidism due to autoimmune thyroiditis

Влияние регуляторов роста на урожайность и качество картофеля

The potato is one of the most versatile, accessible and at the same time widespread vegetable crops of the globe, and in particular of the Russian Federation. Today notable can be imagined without it. But despite the plasticity of the potato crop, there are still “white spots” in its production. With late and even return spring and early autumn frosts, the climatic features of Siberia significantly affect the crop’s growing season, preventing it from realising its full potential. Like that of many other crops, potato production is associated with seasonality, and there are often significant losses during cultivation and especially during storage. An important challenge is to protect plants during growth and development by applying innovative, environmentally friendly crop protection and stimulation products. Organomineral growth and development regulators were particularly popular. In the work schemes of application of perspective, organomineral growth regulators in conditions of forest-steppe of Western Siberia were tested and perfected. Their influence on the primary phases of growth and development of potatoes and their maturity, and their influence on biometrical parameters of plants, a phytosanitary condition of crops, a crop capacity, and its safety are established. On average, under the influence of growth regulators Epin-Extra and Zircon, the growing season is shortened by 3-5 days; the spread of diseases is reduced by 1.5-2 times; the yield increases to 8.3 tons per hectare. These studies are confirmed by the calculation of economic efficiency. Thus, the use of these growth regulators provides the level of profitability of production up to 252%.Картофель – одна из самых пластичных, доступных и в то же время распространённых овощных культур земного шара и в особенности Российской Федерации. Без неё на сегодняшний день нельзя представить ни одного стола. Но несмотря на пластичность культуры картофеля, есть ещё «белые пятна» в его производстве, особенно в условиях Сибири, климатические особенности которой с поздними и даже возвратными весенними и ранними осенними заморозками существенно влияют на вегетационный период культуры, не позволяя ей в полной мере реализовать свой потенциал. Производство картофеля, как и многих других культур, связано с сезонностью и зачастую наблюдаются большие потери при его выращивании и особенно в период хранения. Важной задачей является защита растений в процессе роста и развития путем применения инновационных экологически приемлемых средств защиты и стимуляции растений. Особую популярность при этом завоевали органоминеральные регуляторы роста и развития растений. В процессе выполнения работы были испытаны и отработаны схемы применения перспективных органоминеральных регуляторов роста в условиях лесостепи Западной Сибири. Установлено их влияние на основные фазы роста и развития картофеля и сроки его созревания, а также оценено их влияние на биометрические параметры растений, фитосанитарное состояние посевов, урожайность и его сохранность. В среднем под действием регуляторов роста Эпин-Экстра и Циркон отмечается сокращение периода вегетации на 3 – 5 дней, снижается распространение болезней в 1,5 2 раза и, как следствие, повышается урожайность до 8,3 т/га. Данные исследования подтверждены расчетом экономической эффективности. Так, применение данных регуляторов роста обеспечивает уровень рентабельности продукции до 252%