Structure, chemical composition, and mechanic properties of bone tissue under the effect of natural zeolites and fluorine

In the experiment with Wistar lab rats, the structure, physical-chemical properties, the strength characteristics of the bone tissue under the joint action of natural zeolites and sodium fluoride are investigated. Morphological studies were carried out with the aid of the atomic-force and scanning electron microscopy. Physical-chemical studies were carried out with the aid of the Raman spectroscopy and the atomic absorption spectrophotometry. Micromechnic tests were conducted by the microindentation method with the use of a micro hardness meter. It was shown that natural zeolites used as food additives and acting together with fluorine imposes an extreme impact on the bone tissue due to hypermineralization effect on membranes of bone canalicules with the secondary disorder of trophics of the bone matrix and the worsening of bone hardness characteristics. These circumstances cast doubt on promises of using zeolite and fluorine-containing medical drugs in osteoporosis correction technologies