First delivery of a COVID-19 positive patient in Cameroon

Since its appearance in China in December 2019, COVID-19 which is caused by the SARS-CoV-2 virus has become a real global health problem. Pregnant women are not immune to this novel infection, which makes it difficult for proper management of pregnancy and childbirth. Authors present here the first case of childbirth in Cameroon of a 19-year-old adolescent tested positive for COVID-19

Effect of hysteresis on water flow in the vadose zone under natural boundary conditions, Siloam Village case study, South Africa

A one-dimensional vadose zone model was used to simulate flow under natural boundary conditions. The effects of hysteresis and temporal variability of meteorological conditions were evaluated. Simulations were performed in HYDRUS-1D code for the period April 2013–January 2014 (6601 hours) at three different locations in a delineated portion of the sub-quaternary catchment A80A of Nzhelele with different soil textures. Soil hydraulic characteristics were estimated in a Rosetta library dynamically linked to the HYDRUS-1D model which is based on the numerical solution of a one-dimensional Richard’s equation. Analysis of the simulation results suggests that ignoring hysteresis for soils of similar textural class does not lead to any significant deviation of the model predicted soil moisture, unlike for soils with different textural classesResearch and Publications Committee (RPC) which is under the Directorate of Research and Innovation of the University of Venda, South Afric

Human NK cells of mice with reconstituted human immune system components require pre-activation to acquire functional competence

To investigate human natural killer (NK)– cell reactivity in vivo we have reconstituted human immune system components by transplantation of human hematopoietic progenitor cells into NODscid IL2Rnull mice. We demonstrate here that this model allows the development of all NK-cell subsets that are also found in human adult peripheral and cord blood, including NKp46CD56 NK cells. Similar to human cord blood, NK cells from these reconstituted mice require preactivation by interleukin-15 to reach the functional competence of human adult NK cells. Mainly the terminally differentiated CD16 NK cells demonstrate lower reactivity without this stimulation. After preactivation, both CD16 and CD16 NK cells efficiently produce interferon- and degranulate in response to stimulation with NK cell–susceptible targets, including K562 erythroleukemia cells. NK-cell lines, established from reconstituted mice, demonstrate cytotoxicity against this tumor cell line. Importantly, preactivation can as well be achieved by bystander cell maturation via poly I:C stimulation in vitro and injection of this maturation stimulus in vivo. Preactivation in vivo enhances killing of human leukocyte antigen class I negative tumor cells after their adoptive transfer. These data suggest that a functional, but resting, NK-cell compartment can be established in immune-compromised mice after human hematopoietic progenitor cell transfer

Mitteilungen aus der Stadtbibliothek in Hamburg ...

"Bericht über die verwaltung der Stadtbibliothek" included in "Mittheilungen", 1887-94.Title varies slightly.Mode of access: Internet.Nos. 1-11, 1884-94, edited by F. Eyssenhardt, librarian, were issued separately; the series was continued irregularly in "Jahrbuch der hamburgischen wissenschaftlichen anstalten" until 1911, after which publication was suspended until 1925, when a new series was begun