2,845 research outputs found
Justice Delayed Is ... Delay Ignored: The Indifference of Judges and Law Professors to Legal Lassitude
The Use of Wearable Technology in the Detection of Operator Fatigue
Introduction: Operator fatigue is a prevalent cause of injury and death. Many studies have proven reliable ways of determining operator fatigue through the use of engineering and technological advances including blink rate, lid lag, respiratory rate, cardiac rate, chest expansion, etc. However the implementation of these advances has yet to be utilized. This systematic literature review seeks to elucidate the need for implementation of wearable technology for those who suffer from operator fatigue.
Methods: The target population includes anyone who operates a vehicle including drivers, aviation pilots, train conductors/engineers, marine pilots, operators of heavy machinery, fishermen and professional/overnight drivers. All technological and engineering interventions used in the detection of operator fatigue will be analyzed with successful detection of driver fatigue being the outcome. Data is being compiled form PubMed, Scopus, Cochrane Library and TRID.
Results: We are in the process of publishing a preferred reporting items for systematic review and meta-analyses protocol (PRISMA-P). In addition, the results from each database suggest wearable technology is successful in detecting operator fatigue.
Discussion: The PRISMA-P is a necessary step to provide validity for a systematic literature review to show we aren’t manipulating parameters to skew our results. Upon publishing this, we anticipate that our PRISMA P will further support the need for a systematic literature review on the use of wearable technology in the detection of operator fatigue
Cif Is Negatively Regulated by the TetR Family Repressor CifR
We previously reported that the novel Pseudomonas aeruginosa toxin Cif is capable of decreasing apical membrane expression of the cystic fibrosis transmembrane conductance regulator (CFTR). We further demonstrated that Cif is capable of degrading the synthetic epoxide hydrolase (EH) substrate S-NEPC [(2S,3S)-trans-3-phenyl-2-oxiranylmethyl 4-nitrophenol carbonate], suggesting that Cif may be reducing apical membrane expression of CFTR via its EH activity. Here we report that Cif is capable of degrading the xenobiotic epoxide epibromohydrin (EBH) to its vicinal diol 3-bromo-1,2-propanediol. We also demonstrate that this epoxide is a potent inducer of cif gene expression. We show that the predicted TetR family transcriptional repressor encoded by the PA2931 gene, which is immediately adjacent to and divergently transcribed from the cif-containing, three-gene operon, negatively regulates cif gene expression by binding to the promoter region immediately upstream of the cif-containing operon. Furthermore, this protein-DNA interaction is disrupted by the epoxide EBH in vitro, suggesting that the binding of EBH by the PA2931 protein product drives the disassociation from its DNA-binding site. Given its role as a repressor of cif gene expression, we have renamed PA2931 as CifR. Finally, we demonstrate that P. aeruginosa strains isolated from cystic fibrosis patient sputum with increased cif gene expression are impaired for the expression of the cifR gene
Resonance-like piezoelectric electron-phonon interaction in layered structures
We show that mismatch of the piezoelectric parameters between layers of
multiple-quantum well structures leads to modification of the electron-phonon
interaction. In particular, short-wavelength phonons propagating perpendicular
to the layers with wavevector close to , where is the period of
the structure, induce a strong smoothly-varying component of the
piezo-potential. As a result, they interact efficiently with 2D electrons. It
is shown, that this property leads to emission of collimated
quasi-monochromatic beams of high-frequency acoustic phonons from hot electrons
in multiple-quantum well structures. We argue that this effect is responsible
for the recently reported monochromatic transverse phonon emission from
optically excited GaAs/AlAs superlattices, and provide additional experimental
evidences of this.Comment: 6 pages, 7 figure
PROCEEDINGS OF THE 2019 CALIFORNIA WATER LAW SYMPOSIUM PANEL ORGANIZED BY GGU SCHOOL OF LAW: SGMA AND INTERCONNECTED GROUNDWATERSURFACE WATER
California’s Sustainable Groundwater Management Act (“SGMA”) has been the topic of many discussions since its enactment in 2014. The overarching goal of SGMA is to achieve sustainable groundwater basins through management plans “without causing undesirable results.” Considering the importance and magnitude of this task, it comes as no surprise that SGMA was the theme for the February 2019 California Water Law Symposium, held at the University of California (“UC”), Hastings College of Law in San Francisco. For the Symposium, Golden Gate University School of Law (“GGU”) students gathered a panel of experts to explore the relationship between groundwater plans and surface water within the context of SGMA. The GGU panel focused on issues stemming from the hydrological connections — particularly the undesirable results — between surface water and groundwater, impacts on fisheries, and the public trust doctrine
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