Sensitivity of the Cherenkov Telescope Array to TeV photon emission from the Large Magellanic Cloud

A deep survey of the Large Magellanic Cloud at ∼0.1–100 TeV photon energies with the Cherenkov Telescope Array is planned. We assess the detection prospects based on a model for the emission of the galaxy, comprising the four known TeV emitters, mock populations of sources, and interstellar emission on galactic scales. We also assess the detectability of 30 Doradus and SN 1987A, and the constraints that can be derived on the nature of dark matter. The survey will allow for fine spectral studies of N 157B, N 132D, LMC P3, and 30 Doradus C, and half a dozen other sources should be revealed, mainly pulsar-powered objects. The remnant from SN 1987A could be detected if it produces cosmic-ray nuclei with a flat power-law spectrum at high energies, or with a steeper index 2.3–2.4 pending a flux increase by a factor of >3–4 over ∼2015–2035. Large-scale interstellar emission remains mostly out of reach of the survey if its >10 GeV spectrum has a soft photon index ∼2.7, but degree-scale 0.1–10 TeV pion-decay emission could be detected if the cosmic-ray spectrum hardens above >100 GeV. The 30 Doradus star-forming region is detectable if acceleration efficiency is on the order of 1−10 per cent of the mechanical luminosity and diffusion is suppressed by two orders of magnitude within <100 pc. Finally, the survey could probe the canonical velocity-averaged cross-section for self-annihilation of weakly interacting massive particles for cuspy Navarro–Frenk–White profiles

Parameter Sensitivity for In Vitro Anthrax Studies

Studies done on interactions between spores and macrophages done in vitro show inconsistent results based on experimental protocol and inhibit meaningful extrapolation to in vivo. In this study, we perform a sensitivity analysis of a model representing in vitro studies of interactions between anthrax spores and macrophages to help address the effects of these inconsistencies. We perform both local and global analyses using Latin hypercube sampling and partial rank correlation coefficients. Our analysis indicates the amount of intracellular bacteria over time is most sensitive to the killing of intracellular bacteria by the macrophages and replication of the bacteria inside the macrophage. Extracellular germination rates are shown to affect the amount of intracellular bacteria only during the incubation period, due to the assumption that any remaining extracellular bacteria is assumed to be washed away after the incubation period

Bessel-Gauss beams of arbitrary integer order: propagation profile, coherence properties and quality factor

We present a novel approach to generate Bessel-Gauss modes of arbitrary integer order and well-defined optical angular momentum in a gradient index medium of transverse parabolic profile. The propagation and coherence properties, as well as the quality factor, are studied using algebraic techniques that are widely used in quantum mechanics. It is found that imposing the well-defined optical angular momentum condition, the Lie group $SU(1,1)$ comes to light as a characteristic symmetry of the Bessel-Gauss beams.Comment: 24 pages, 12 figure