Benefit of irrigation water transfers in the National River Linking Project: a case study of the Ken-Betwa link

River basin managementRiver basin developmentDevelopment projectsWater transferIrrigation waterCrop productionCrop managementLivestock

Two Gallium data sets, spin flavour precession and KamLAND

We reexamine the possibility of a time modulation of the low energy solar neutrino flux which is suggested by the average decrease of the Ga data in line with our previous arguments. We perform two separate fits to the solar neutrino data, one corresponding to 'high' and the other to 'low' Ga data, associated with low and high solar activity respectively. We therefore consider an alternative to the conventional solar+KamLAND fitting, which allows one to explore the much wider range of the $\theta_{12}$ angle permitted by the KamLAND fitting alone. We find a solution with parameters $\Delta m^2_{21}=8.2\times 10^{-5} eV^2, tan^{2}\theta=0.31$ in which the 'high' and the 'low' Ga rates lie far apart and are close to their central values and is of comparable quality to the global best fit, where these rates lie much closer to each other. This is an indication that the best fit in which all solar and KamLAND data are used is not a good measure of the separation of the two Ga data sets, as the information from the low energy neutrino modulation is dissimulated in the wealth of data. Furthermore for the parameter set proposed one obtains an equally good fit to the KamLAND energy spectrum and an even better fit than the 'conventional' LMA one for the reactor antineutrino survival probability as measured by KamLAND.Comment: V2: 15 pages, 3 eps figures, fit improved, final version to appear in Journal of Physics

Tenure clock policy transparency for biological clock (family friendly) events

The intention of this study is to investigate the transparency of information on university websites regarding the policies in place related to leave and/or tenure clock extensions for child-related events such as childbirth, adoption, or placement of a foster child. The main purpose is to improve awareness about the policies existing in academia related to these events. The secondary purpose is to determine whether major institutional characteristics affect the family-friendly policies of these institutions. Nearly 80% of the institutions studied communicated some type of information on their website related to tenure clock extension policies. An analysis of the data from these colleges/universities is provided so that other institutions who are developing or reviewing their own policies are aware of the typical policies provided by other institutions. The study found significant differences in policy availability and attributes based on major institutional characteristics

Seaweeds A Potential Source for Functional Foods

Seaweeds are microalgae growing in coastal regions and resistant to salinity. Seaweeds are rich resources of natural nutrients some of which cannot be obtained from terrestrial plants. Bioactive compounds of seaweeds such as sulphated polysaccharides, peptides, minerals, phlorotannins, carotenoids and sulfolipids have proven health benefits against various diseases. Traditionally, seaweeds are used as folk medicine for treating diseases like goiter, wounds, burns, rashes, inflammation, diabetes and also gaining attention of pharmaceutical industries due to their anti-cancer, anti-aging, anti-angiogenesis, anti-bacterial, anti-viral and antioxidant properties. Seaweeds polysaccharides have wide applications in foods as well as in pharmaceutical industry due to their bio-chemical properties such as stabilizer, emulsifier and gelling property. In food industry, seaweed polysaccharides are used as a functional ingredient in many products such as frozen foods, ice-cream, jam, jelly, beverages etc. Several commercial food preparations from seaweeds are also available in the market such as sea salt, nori snack wasabi, pink rock salt, seaweed thins toasted coconuts, crunchy seaweed chips, raw unroasted seaweed under different brand names. The present review is a compilation of nutritional, pharmacological and food properties of seaweeds along with its potential towards development of functional foods

Retrieval of sea surface velocities using sequential Ocean Colour Monitor (OCM) data

The Indian remote sensing satellite, IRS-P4 (Oceansat-I) launched on May 26th, 1999 carried two sensors on board, i.e., the Ocean Colour Monitor (OCM) and the Multi-frequency Scanning Microwave Radiometer (MSMR) dedicated for oceanographic research. Sequential data of IRS-P4 OCM has been analysed over parts of both east and west coast of India and a methodology to retrieve sea surface current velocities has been applied. The method is based on matching suspended sediment dispersion patterns, in sequential two time lapsed images. The pattern matching is performed on a pair of atmospherically corrected and geo-referenced sequential images by Maximum Cross-Correlation (MCC) technique. The MCC technique involves computing matrices of cross-correlation coefficients and identifying correlation peaks. The movement of the pattern can be calculated knowing the displacement of windows required to match patterns in successive images. The technique provides actual flow during a specified period by integrating both tidal and wind influences. The current velocities retrieved were compared with synchronous data collected along the east coast during the GSI cruise ST-133 of R.V. Samudra Kaustubh in January 2000. The current data were measured using the ocean current meter supplied by the Environmental Measurement and CONtrol (EMCON), Kochi available with the Geological Survey of India, Marine Wing. This current meter can measure direction and magnitude with an accuracy of ±5‡ and 2% respectively. The measurement accuracies with coefficient of determination (R2 ) of 0.99, for both magnitude (cm.s-1) and direction (deg.) were achieved

An immunotherapy survivor population: health-related quality of life and toxicity in patients with metastatic melanoma treated with immune checkpoint inhibitors

© The Author(s) 2019. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.Purpose The immune checkpoint inhibitors (ICIs) have resulted in subgroups of patients with metastatic melanoma achievinghigh-quality durable responses. Metastatic melanoma survivors are a new population in the era of cancer survivorship. The aimofthis study was to evaluate metastatic melanoma survivors in terms of health-related quality of life (HRQoL), immune-relatedadverse events (irAEs) and exposure to immunosuppressive agents in a large single centre in the UK.Methods We defined the survivor population as patients with a diagnosis of metastatic melanoma who achieved a durableresponse to an ICI and had been followed-up for a minimum of 12 months from initiation of ICI without disease progression.HRQoL was assessed using SF-36. Electronic health records were accessed to collect data on demographics, treatments, irAEsand survival. HRQoL data was compared with two norm-based datasets.Results Eighty-four metastatic melanoma survivors were eligible and 87% (N = 73) completed the SF-36. ICI-related toxicity ofany grade occurred in 92%of patients and 43%had experienced a grade 3 or 4 toxicity. Almost half (49%) of the patients requiredsteroids for the treatment of ICI-related toxicity, whilst 14% required treatment with an immunosuppressive agent beyondsteroids.Melanoma survivors had statistically significant lower HRQoL scores with regard to physical, social and physical rolefunctioning and general health compared with the normative population. There was a trend towards inferior scores in patientswith previous exposure to ipilimumab compared with those never exposed to ipilimumab.Conclusions Our results show that metastatic melanoma survivors have potentially experienced significant ICI-related toxicityand experience significant impairments in specific HRQoL domains. Future service planning is required to meet this population’sunique survivorship needs.Peer reviewe