When four months equal a year: An exploration of inconsistencies in students' monthly versus yearly reports of drug use

https://deepblue.lib.umich.edu/bitstream/2027.42/137903/1/occ9.pd

The impacts of response styles on black-white differences in self-esteem: An analysis of six samples of youth

https://deepblue.lib.umich.edu/bitstream/2027.42/137900/1/occ16.pd

Interleukin-6 Modulates Colonic Transepithelial Ion Transport in the Stress-Sensitive Wistar Kyoto Rat

Immunological challenge stimulates secretion of the pro-inflammatory cytokine interleukin (IL)-6, resulting in variety of biological responses. In the gastrointestinal tract, IL-6 modulates the excitability of submucosal neurons and stimulates secretion into the colonic lumen. When considered in the context of the functional bowel disorder, irritable bowel syndrome (IBS), where plasma levels of IL-6 are elevated, this may reflect an important molecular mechanism contributing to symptom flares, particularly in the diarrhea-predominant phenotype. In these studies, colonic ion transport, an indicator of absorption and secretion, was assessed in the stress-sensitive Wistar Kyoto (WKY) rat model of IBS. Mucosa-submucosal colonic preparations from WKY and control Sprague Dawley (SD) rats were mounted in Ussing chambers and the basal short circuit current (I(SC)) was electrophysiologically recorded and compared between the strains. Exposure to IL-6 (1 nM) stimulated a secretory current of greater amplitude in WKY as compared to SD samples. Furthermore, the observed IL-6-mediated potentiation of secretory currents evoked by veratridine and capsaicin in SD rats was blunted in WKY rats. Exposure to IL-6 also stimulated an increase in transepithelial resistance in both SD and WKY colonic tissue. These studies demonstrate that the neuroexcitatory effects of IL-6 on submucosal plexi have functional consequences with alterations in both colonic secretory activity and permeability. The IL-6-induced increase in colonic secretory activity appears to neurally mediated. Thus, local increases in IL-6 levels and subsequent activation of enteric neurons may underlie alterations in absorpto-secretory function in the WKY model of IBS

Change and consistency in the correlates of drug use among high school seniors: 1975-1986

https://deepblue.lib.umich.edu/bitstream/2027.42/137898/1/occ21.pd

National survey results on drug use from the Monitoring the Future study, 1975-1992. Volume I: Secondary school students.

https://deepblue.lib.umich.edu/bitstream/2027.42/137824/1/mtf-vol1_1992.pd

The Monitoring the Future project after twenty-two years: Design and procedures

https://deepblue.lib.umich.edu/bitstream/2027.42/137888/1/occ38.pd

Highlights from drugs and the class of '78: Behaviors, attitudes and recent national trends.

https://deepblue.lib.umich.edu/bitstream/2027.42/137846/1/mtf-highlights_1978.pd

National survey results on drug use from the Monitoring the Future study, 1975-1995. Volume I: Secondary school students.

https://deepblue.lib.umich.edu/bitstream/2027.42/137816/1/mtf-vol1_1995.pd

Drug use among American high school seniors, college students and young adults, 1975-1990. Volume II: College students and young adults.

https://deepblue.lib.umich.edu/bitstream/2027.42/137830/1/mtf-vol2_1990.pd

Differentiation of period, age, and cohort effects on drug use 1976-1986

https://deepblue.lib.umich.edu/bitstream/2027.42/137896/1/occ22.pd