Clinical features of low back pain in people with hip osteoarthritis: A cross sectional study.

BACKGROUND: Low back pain (LBP) is commonly reported in people with hip osteoarthritis (OA) and is a poor prognostic indicator of outcome in OA. This study aimed to identify the clinical features associated with LBP in people with hip OA attending orthopaedic and rheumatology clinics. METHODS: A cross-sectional study was undertaken. Twenty-four people with radiographically confirmed OA were recruited and completed self-report questionnaires for hip and LBP severity (Visual Analogue Scale), hip-related disability (Western Ontario and McMaster Universities Osteoarthritis Index) and back-related disability (Roland Morris Disability Questionnaire). Physical examination comprised spinal palpation, pelvic girdle pain provocation tests and hip and spinal range of motion tests. Between-group (presence/absence of LBP) differences in self-report and physical examination items were compared using Mann-Whitney U and Chi-squared tests. RESULTS: A total of 16/24 (66.7%) patients reported LBP. Those with LBP were younger, reported more pain locations and had higher self-report pain and disability. On physical examination, people with LBP and OA hip had reduced hip flexion, greater pain provocation with hip abduction, hip lateral rotation, spinal palpation and a greater number of painful pelvic girdle tests and spinal level palpation. CONCLUSIONS: Assessment of patients with hip OA should incorporate examination of the lumbar spine and pelvic regions. It appears from our study that LBP is a common co-morbidity in those with OA of the hip and may indicate greater severity of hip disease, although the small sample size limits interpretation of results. Further research should investigate the exact relationships between presence of LBP and hip OA

Research Reference Document 01/19 : Kennebec River Diadromous Fish Restoration Annual Progress Report (2001)

https://digitalmaine.com/dmr_research_reference_documents/1004/thumbnail.jp

Research Reference Document 00/18 : Restoring Our Native Fish Resources : Kennebec River Diadromous Fish Restoration Annual Progress Report - 2000

https://digitalmaine.com/dmr_research_reference_documents/1002/thumbnail.jp

Mapping Crustal Shear Wave Velocity Structure and Radial Anisotropy Beneath West Antarctica Using Seismic Ambient Noise

Using 8- to 25-s-period Rayleigh and Love wave phase velocity dispersion data extracted from seismic ambient noise, we (i) model the 3-D shear wave velocity structure of the West Antarctic crust and (ii) map variations in crustal radial anisotropy. Enhanced regional resolution is offered by the UK Antarctic Seismic Network. In the West Antarctic Rift System (WARS), a ridge of crust ∼26–30km thick extending south from Marie Byrd Land separates domains of more extended crust (∼22km thick) in the Ross and Amundsen Sea Embayments, suggesting along-strike variability in the Cenozoic evolution of the WARS. The southern margin of the WARS is defined along the southern Transantarctic Mountains and Haag-Ellsworth Whitmore Mountains (HEW) block by a sharp crustal thickness gradient. Crust ∼35–40km is modeled beneath the Haag Nunataks-Ellsworth Mountains, decreasing to ∼30–32km thick beneath the Whitmore Mountains, reflecting distinct structural domains within the composite HEW block. Our analysis suggests that the lower crust and potentially the middle crust is positively radially anisotropic (VSH \u3e VSV) across West Antarctica. The strongest anisotropic signature is observed in the HEW block, emphasizing its unique provenance among West Antarctica\u27s crustal units, and conceivably reflects a ∼13-km-thick metasedimentary succession atop Precambrian metamorphic basement. Positive radial anisotropy in the WARS crust is consistent with observations in extensional settings and likely reflects the lattice-preferred orientation of minerals such as mica and amphibole by extensional deformation. Our observations support a contention that anisotropy may be ubiquitous in the continental crust

What Provosts Think Librarians Should Know

Three senior leaders will reveal what Provosts worry about when they think about libraries. Charged to be frank and direct, they will talk about what they value in libraries, but also about what the challenges are that they face that affect how they think about libraries. Budget, facilities, and their perception of what faculty and students want and need will all play into this. This session is an opportunity for a frank exchange of views with real provosts—without worrying about how they react

Marketing and value-added opportunities with alternative swine systems

Jan O\u27Donnell is the executive director of the Minnesota Food Association, a nonprofit membership organization dedicated to forming a coalition of food producers and consumers to build a more sustainable food system. Paul Willis shared his experiences in developing a relationship with a West Coast company to market high-quality pork

Pulmonary hypertension is a manifestation of congestive heart failure and left ventricular diastolic dysfunction in octogenarians with severe aortic stenosis

Previous studies have suggested that pulmonary hypertension (PH) in severe aortic stenosis (AS) is a risk factor for operative mortality with aortic valve replacement (AVR). Conversely, others have shown that patients with AS and PH extract a large symptomatic and survival benefit from AVR compared with those patients not treated surgically. We sought to evaluate the prevalence, severity, and mechanism of PH in an elderly patient cohort with severe AS. We prospectively evaluated 41 patients aged ≥80 years with severe AS. All patients underwent cardiac catheterization and transthoracic echocardiography within 24 hours. We found that PH was common in this cohort: 32 patients (78%) had PH; however, the predominant mechanism of PH was left heart congestion. Patients with PH had nearly double the pulmonary artery wedge pressure of patients without PH (23 vs. 13 mmHg; P ≤ 0.001). In patients with PH compared with those without, pulmonary vascular resistance was higher yet still under 3 Wood units (WU; 2.9 vs. 1.5 WU; P = 0.001), and the transpulmonary gradient (11 vs. 7 mmHg; P = 0.01) and diastolic pulmonary gradient (DPG; 3.0 vs. 2.7 mmHg; P = 0.74) were in normal range. Left ventricular diastolic abnormalities were more common in patients with severe AS and PH. Right ventricular (RV) dysfunction was common (13/41 patients, 32%), but the PH and non-PH groups had similar tricuspid annular plane systolic excursion (2.0 vs. 2.3 cm; P = 0.15). Only 2 subjects had both RV dysfunction and an elevated DPG. In conclusion, PH is common in elderly patients with severe AS. This occurs largely due to left heart congestion, with a relative absence of pulmonary vascular disease and RV dysfunction, and as such, PH may serve as a heart failure equivalent in these patients

Mobilized Peripheral Blood Stem Cells Versus Unstimulated Bone Marrow As a Graft Source for T-Cell-Replete Haploidentical Donor Transplantation Using Post-Transplant Cyclophosphamide.

Purpose T-cell-replete HLA-haploidentical donor hematopoietic transplantation using post-transplant cyclophosphamide was originally described using bone marrow (BM). With increasing use of mobilized peripheral blood (PB), we compared transplant outcomes after PB and BM transplants. Patients and Methods A total of 681 patients with hematologic malignancy who underwent transplantation in the United States between 2009 and 2014 received BM (n = 481) or PB (n = 190) grafts. Cox regression models were built to examine differences in transplant outcomes by graft type, adjusting for patient, disease, and transplant characteristics. Results Hematopoietic recovery was similar after transplantation of BM and PB (28-day neutrophil recovery, 88% v 93%, P = .07; 100-day platelet recovery, 88% v 85%, P = .33). Risks of grade 2 to 4 acute (hazard ratio [HR], 0.45; P \u3c .001) and chronic (HR, 0.35; P \u3c .001) graft-versus-host disease were lower with transplantation of BM compared with PB. There were no significant differences in overall survival by graft type (HR, 0.99; P = .98), with rates of 54% and 57% at 2 years after transplantation of BM and PB, respectively. There were no differences in nonrelapse mortality risks (HR, 0.92; P = .74) but relapse risks were higher after transplantation of BM (HR, 1.49; P = .009). Additional exploration confirmed that the higher relapse risks after transplantation of BM were limited to patients with leukemia (HR, 1.73; P = .002) and not lymphoma (HR, 0.87; P = .64). Conclusion PB and BM grafts are suitable for haploidentical transplantation with the post-transplant cyclophosphamide approach but with differing patterns of treatment failure. Although, to our knowledge, this is the most comprehensive comparison, these findings must be validated in a randomized prospective comparison with adequate follow-up