Microbubbles and Cavitation

The present report arose from a joint effort of the California Institute of Technology, The Catholic University of America and the David Taylor Naval Ship Research and Development Center. The initial purpose was to document by both light-scattering and holographic techniques the distribution of microbubbles in laboratory cavitation test facilities (under different conditions of cavitation testing), to compare these two different techniques where feasible and then, as the last stage, to make similar observations of nuclei in natural or oceanic waters. It has been apparent to many workers in the field of cavitation inception that there has not yet been adequate correlation of laboratory and field conditions for cavitation testing - particularly for cavitation inception testing. Thus the proposed work offered the first real opportunity to explore this important connection. Caltech's role in this work was to design and build a holographic system that would be suitable for use either in the laboratory or the field. In the first case we anticipated making laboratory nuclei observations in the Institute's Low Turbulence Water Tunnel (LTWT) jointly with the light-scattering device designed by Professor S. C. Ling of C.U.A. and developed further by Mr. S. Gowing of DTNSRDC. For the latter case, the field work, it was proposed to install the holographic system in a submersible tank to permit holographic recordings of a suitable test volume of fluid. As an initial goal a depth of 100 feet was selected for the maximum depth of operation

Enumeration of distinct mechanically stable disk packings in small systems

We create mechanically stable (MS) packings of bidisperse disks using an algorithm in which we successively grow or shrink soft repulsive disks followed by energy minimization until the overlaps are vanishingly small. We focus on small systems because this enables us to enumerate nearly all distinct MS packings. We measure the probability to obtain a MS packing at packing fraction $\phi$ and find several notable results. First, the probability is highly nonuniform. When averaged over narrow packing fraction intervals, the most probable MS packing occurs at the highest $\phi$ and the probability decays exponentially with decreasing $\phi$. Even more striking, within each packing-fraction interval, the probability can vary by many orders of magnitude. By using two different packing-generation protocols, we show that these results are robust and the packing frequencies do not change qualitatively with different protocols.Comment: 4 pages, 3 figures, Conference Proceedings for X International Workshop on Disordered System

HIV-1 and the Mycobacterium tuberculosis granuloma: A systematic review and meta-analysis

SummaryInfection with HIV-1 greatly increases the risk of active tuberculosis (TB). Although hypotheses suggest HIV-1 disrupts Mycobacterium tuberculosis (Mtb) granuloma function, few studies have examined this directly. The objective of this study was to determine what evidence exists about the effect HIV-1 co-infection has upon Mtb granulomas. A systematic search of PubMed, Web of Science, and Medline up to 20 March 2015 was conducted, to identify studies comparing Mtb-infected tissue from HIV-1 infected and uninfected persons, or HIV-1 infected persons with stratified peripheral CD4 T cell (pCD4) counts. We summarized findings that focused on how HIV-1 changes granuloma formation, bacterial presence, cellular composition, and cytokine production. Nineteen studies with a combined sample size of 899 persons were included. Although studies frequently were limited by variable or inadequately described definitions of outcomes and analytical methods, HIV-1 was found to be associated with increased bacillary load within Mtb-infected tissue. Reductions in pCD4 counts within co-infected persons associated with both poorer granuloma formation and higher bacterial load. The high degree of heterogeneity among studies combined with experimental limitations made it difficult to conclusively support previously published and prevalent hypotheses about HIV-1/Mtb co-infection granulomas. To elucidate the validity of these hypotheses we have described areas that can be improved in future studies in order to clarify the influence HIV-1 co-infection has upon the Mtb granuloma

Sliding Phases in XY-Models, Crystals, and Cationic Lipid-DNA Complexes

We predict the existence of a totally new class of phases in weakly coupled, three-dimensional stacks of two-dimensional (2D) XY-models. These ``sliding phases'' behave essentially like decoupled, independent 2D XY-models with precisely zero free energy cost associated with rotating spins in one layer relative to those in neighboring layers. As a result, the two-point spin correlation function decays algebraically with in-plane separation. Our results, which contradict past studies because we include higher-gradient couplings between layers, also apply to crystals and may explain recently observed behavior in cationic lipid-DNA complexes.Comment: 4 pages of double column text in REVTEX format and 1 postscript figur

Two dimensional anisotropic non Fermi-liquid phase of coupled Luttinger liquids

We show using bosonization techniques, that strong forward scattering interactions between one dimensional spinless Luttinger liquids (LL) can stabilize a phase where charge-density wave, superconducting and transverse single particle hopping perturbations are irrelevant. This new phase retains its LL like properties in the directions of the chains, but with relations between exponents modified by the transverse interactions, whereas, it is a perfect insulator in the transverse direction. The mechanism that stabilizes this phase are strong transverse charge density wave fluctuations at incommensurate wavevector, which frustrates crystal formation by preventing lock-in of the in-chain density waves.Comment: (4 pages, 2 figures

Glass transition in granular media

In the framework of schematic hard spheres lattice models for granular media we investigate the phenomenon of the ``jamming transition''. In particular, using Edwards' approach, by analytical calculations at a mean field level, we derive the system phase diagram and show that ``jamming'' corresponds to a phase transition from a ``fluid'' to a ``glassy'' phase, observed when crystallization is avoided. Interestingly, the nature of such a ``glassy'' phase turns out to be the same found in mean field models for glass formers.Comment: 7 pages, 4 figure