Technical appraisal of some maize shellers in Oyo and Kwara States of Nigeria

This study assessed the performance of some maize shellers in use in grain markets in Oyo and Kwara States, Nigeria. A preliminary survey conducted identified shellers in use as basic maize sheller (BMS) without blower, maize sheller with blower attachment (MSB) and the multi-purpose sheller (MPS). The shelling/cleaning performance of the shellers were assessed using yellow maize (SWAN 1 variety) and some key equipment parameters, which impact performance were measured. The air velocity for MSB and MPS ranged between 0.4 and 2.4 m/s which was not sufficient for efficient cleaning of chaff from shelled grains. Shaft speed for BMS, MSB and MPS were 845, 920 and 820 rpm, respectively. Average throughput for BMS, MSB and MPS was 1,714, 600 and 840 kg/hr, respectively with mean shelling efficiencies of 92.9, 82.7 and 97.9%, respectively. Mean cleaning efficiencies were 54.0 and 57.7% for MSB and MPS, respectively. The percentage grain loss for BMS, MSB and MPS were 17, 7.1 and 1.9%, respectively. It was observed that many fabricators do not consult agricultural engineers when producing machines, relying more on previous experience. Additionally, there was a lack of consideration for operator safety with the exposure of moving parts of the equipment in all the designs evaluated. A key recommendation from this study is that sheller designs should be standardized to ensure the provision of quality and highly efficient machinery for processors

In vivo quantitative imaging of hippocampal inflammation in autoimmune neuroinflammatory conditions: a systematic review

The hippocampus is a morphologically complex region of the brain limbic system centrally involved in important cognitive, affective, and behavioural regulatory roles. It has exquisite vulnerability to neuroinflammatory processes, with some of its subregions found to be specific sites of neuroinflammatory pathology in ex-vivo studies. Optimising neuroimaging correlates of hippocampal neuroinflammation would enable direct study of functional consequences of hippocampal neuroinflammatory pathology, as well as the definition of therapeutic end points for treatments targeting neuroinflammation, and their related affective or cognitive sequelae. However, in vivo traditional imaging of the hippocampus and its subregions is fraught with difficulties, due to methodological challenges deriving from its unique anatomical characteristics. The main objective of this review is to provide a current update on the characterisation of quantitative neuroimaging correlates of hippocampal neuroinflammation, by focusing on three prototypical autoimmune neuro-inflammatory conditions [Multiple Sclerosis (MS), Systemic Lupus Erythematosus- (SLE), Autoimmune Encephalitis (AE)]. We focused on studies employing TSPO-targeting Positron Emission Tomography (PET), and Quantitative Magnetic Resonance Imaging (MRI) and Spectroscopy techniques assumed to be sensitive to neuroinflammatory tissue changes. We found 18 eligible studies (14, 2 and 2 studies in MS, AE and SLE respectively). Across conditions, the largest effect was seen in TSPO PET and diffusion weighted MRI studies. No study examined neuroinflammation-related changes at hippocampal subfields level. Overall, results were largely inconsistent due to heterogeneous imaging methods, small sample sizes and different population studies. We discuss how these data could inform future study design and conclude by suggesting further methodological directions aimed at improving precision and sensitivity of neuroimaging techniques to characterise hippocampal neuroinflammatory pathology in the human brain

Technical Appraisal of some Maize Shellers in Oyo and Kwara States of Nigeria

This study assessed the performance of some maize shellers in use in grain markets in Oyo and Kwara States, Nigeria. A preliminary survey conducted identified shellers in use as basic maize sheller (BMS) without blower, maize sheller with blower attachment (MSB) and the multi-purpose sheller (MPS). The shelling/cleaning performance of the shellers were assessed using yellow maize (SWAN 1 variety) and some key equipment parameters, which impact performance were measured. The air velocity for MSB and MPS ranged between 0.4 and 2.4 m/s which was not sufficient for efficient cleaning of chaff from shelled grains. Shaft speed for BMS, MSB and MPS were 845, 920 and 820 rpm, respectively. Average throughput for BMS, MSB and MPS was 1,714, 600 and 840 kg/hr, respectively with mean shelling efficiencies of 92.9, 82.7 and 97.9%, respectively. Mean cleaning efficiencies were 54.0 and 57.7% for MSB and MPS, respectively. The percentage grain loss for BMS, MSB and MPS were 17, 7.1 and 1.9%, respectively. It was observed that many fabricators do not consult agricultural engineers when producing machines, relying more on previous experience. Additionally, there was a lack of consideration for operator safety with the exposure of moving parts of the equipment in all the designs evaluated.  A key recommendation from this study is that sheller designs should be standardized to ensure the provision of quality and highly efficient machinery for processors