Animal Cruelty: A Review

Animal Cruelty cases make headlines around the world every day, whether it’s the person who kills the neighbour’s cat, the hoarder of sick and dying animals or the family whose freezing, starving dog is tied up outside in the middle of the winter. Animal Cruelty has several types which may be one of Simple Neglect, Gross Neglect, Intentional Abuse, Animal Hoarding, Organized Abuse, Ritualistic Abuse or Animal Sexual Assault. These cases of Cruelty cannot be overlooked as it has proven to have severe implications ranging from the fact that it is linked to other crimes, to the factual truth that these practises inflict great pain on these animals that have nobody to speak for them. Combating this menace of Animal Cruelty is a Journey that must be undertaken and everybody including the Government, NGOs and even Culture has a major role to play in this.  This review looks at Animal Cruelty in the world while paying a little more attention to Nigeria

Characterizing the weather band variability of the Texas shelf current

Considering the benefits of understanding the circulation patterns of the shelf, it is not surprising that there are numerous studies of the Texas Shelf circulation patterns. Given that previous studies were focused on the low-frequency variability of the circulation which is upcoast (northeast flow) in the summer and downcoast (southwest flow) especially on the inner shelf in the non-summer seasons, this study investigates the weather band (2–15 days) variability of the Texas Shelf near-surface circulation pattern. Current meter data at 1.5 m below the sea surface from the inner, mid, and outer shelves were analyzed. This study demonstrated that there are high-frequency current reversals within the weather band in each season. From the estimated persistence of the currents during reversals, the inner and mid shelf currents are predominantly downcoast in the non-summer seasons and upcoast in the summer season whereas the outer shelf currents are mostly upcoast all year round. The Wavelets analysis of the currents revealed that most of the variabilities on the inner and mid shelf regions were within the 4-12-day band whereas on the outer shelf the dominant variability was within the 3–8-day band. From the cross-spectra analysis of both the currents and wind data, it was determined that the influence of the wind was more dominant on the inner and mid shelf regions at the 8–15-day band than on the outer shelf where the contribution of the wind is prevalent at the 2–4-day band

Persistence of onchocerciasis in villages in Enugu and Ogun states in Nigeria following many rounds of mass distribution of ivermectin

BACKGROUND: Onchocerciasis is endemic in most local government areas (LGAs) in Enugu and Ogun states. Most meso- and hyper-endemic LGAs have received many rounds of ivermectin mass drug administration (MDA). This study aimed to determine the current prevalence of onchocerciasis in villages in Enugu and Ogun states that were formerly highly endemic and to assess progress toward elimination of the infection in areas believed to be at high risk for persistence. METHODS: Cross-sectional community surveys were conducted 8 to 12 months after the last round of MDA in 16 villages (6 in Enugu state and 10 in Ogun state) in individuals aged ≥ 18 years. Study participants were examined for the presence of palpable subcutaneous nodules. Skin snips from the posterior iliac crests were used to assess microfiladermia (Mf) prevalence and density. RESULTS: 643 subjects were palpated for nodules and 627 individuals (225 in Enugu state; 402 in Ogun state) provided skin snips. Nodule prevalence in the study villages ranged from 42 to 66.7% in Enugu state and from 0 to 25.0% in Ogun state. Mf prevalence in the Enugu and Ogun study villages ranged from 32 to 51.1% and 0 to 28.6%, respectively. Geometric mean skin Mf density in surveyed Enugu state villages ranged between 1 and 3.1 Mf/mg; these values were \u3c 1 Mf/mg in all but one community in Ogun state villages. CONCLUSION: Results from this study show that onchocerciasis persists in adults in many villages in Enugu and Ogun states despite many prior rounds of ivermectin MDA. Prevalence was higher in villages surveyed in Enugu than in Ogun. Low Mf densities suggest the MDA program is working well to reduce disease, but more time will be required to reach the elimination goal

Dark Energy or Apparent Acceleration Due to a Relativistic Cosmological Model More Complex than FLRW?

We use the Szekeres inhomogeneous relativistic models in order to fit supernova combined data sets. We show that with a choice of the spatial curvature function that is guided by current observations, the models fit the supernova data almost as well as the LCDM model without requiring a dark energy component. The Szekeres models were originally derived as an exact solution to Einstein's equations with a general metric that has no symmetries and are regarded as good candidates to model the true lumpy universe that we observe. The null geodesics in these models are not radial. The best fit model found is also consistent with the requirement of spatial flatness at CMB scales. The first results presented here seem to encourage further investigations of apparent acceleration using various inhomogeneous models and other constraints from CMB and large structure need to be explored next.Comment: 6 pages, 1 figure, matches version published in PR

Measurements of Terrestrial Gamma Dose Rate Distributions along Idiroko Road, Ota, Ogun State, Nigeria: Health Implications on Roadside Dwellers

An extensive study concerning the terrestrial gamma dose rates of the surface soils from Canaanland entrance Road, Ota to Eleha Complex along Idiroko Road, Ota has been carried out to cover the road running across both areas. The In-situ measurements of gamma dose rates and radionuclides were carried out using the Gamma detector (Super Spec RS 125). The result shows that the average outdoor gamma dose rate in the study area is 73.57 nGyh-1. The average values of the radionuclides obtained were 32.9 Bq/kg for 238U, 68.4 Bq/kg for 232Th, and 328.7 Bq/kg for 40K. The background dose rate of 113.3 nGy/h was found in station 9 and is twice higher than the recommended permissible limit of 59 nGy/h suggested by UNCSEAR, 2000, and ICRP, 1999, respectively. Results were obtained based on radiological parameters for the outdoor absorbed dose rate (Dout) with a mean value of 73.57 nGyh-1, the indoor absorbed dose rate (Din) with a mean value of 131.84 nGyh-1, the annual effective dose rate (AEDR) with a mean value of 0.74, the radium equivalent (Raeq) with a mean value of 156.0, the internal hazard index (Hin) with a mean value of 0.51, the external hazard index (Hex) with a mean value of 0.42 and the excess lifetime cancer risk (ELCR) with a mean value of 2.57. Similarly, results obtained from estimated radiological parameters show that the station with the highest value for radium equivalent (Raeq), external hazard index (Hex), internal hazard index (Hin), and annual effective dose rate (AEDR) is Station 9 at 237.91 Bq/Kg, 0.64, 0.72 and 1.13 mSvy-1 respectively while the station with the lowest value for radium equivalent (Raeq), external hazard index (Hex), internal hazard index (Hin) and annual effective dose rate (AEDR) is Station 17 at 85.58 Bq/Kg, 0.23, 0.27 and 0.40 mSvy-1 respectively. This study will serve as a guide on assessing the road construction materials on radioactive contents before application to reduce the exposure risks to the populace along the busy roadsides

Rampant introgressive hybridization in Pogoniulus tinkerbirds (Piciformes: Lybiidae) despite millions of years of divergence

Incomplete reproductive isolation between related species of birds at contact zones is increasingly being documented. Such hybridization typically occurs between sister taxa that diverged in relatively recent times, and hybrids are most often identified based on their intermediate phenotypic characteristics and, increasingly, through genetic admixture analysis. When species have been diverging over relatively longer time scales, prezygotic isolation barriers are expected to evolve, precluding maladaptive interbreeding. Here, we examine the extent of introgressive hybridization in a pair of African barbets, the yellow-fronted tinkerbird (Pogoniulus chrysoconus extoni) and the red-fronted tinkerbird (Pogoniulus pusillus pusillus), which were not previously known to interbreed, across a contact zone in Southern Africa. Although there were significant differences in the coloration of plumage between the species, we found a pattern of extensive admixture in and around the contact zone. Nonetheless, the two species appear to have diverged > 4 Mya and might not even be sister taxa, suggesting that time of divergence alone might not be sufficient for the evolution of prezygotic reproductive barriers. Significantly more phenotypically red-fronted individuals had a P. c. extoni (yellow-fronted) genetic background than vice versa, suggesting possible asymmetry in mate preferences. Sexual selection may thus play a role in breaking down species barriers despite the extent of genetic divergence.A Marie Curie International Reintegration Grant (A.N.G.K.) and the A. P. Leventis Ornithological Research Institute (E.C.N. and B.O.O.).https://academic.oup.com/biolinnean2020-04-03hj2019Mammal Research Institut

Clinical implementation of a knowledge based planning tool for prostate VMAT

Abstract Background A knowledge based planning tool has been developed and implemented for prostate VMAT radiotherapy plans providing a target average rectum dose value based on previously achievable values for similar rectum/PTV overlap. The purpose of this planning tool is to highlight sub-optimal clinical plans and to improve plan quality and consistency. Methods A historical cohort of 97 VMAT prostate plans was interrogated using a RayStation script and used to develop a local model for predicting optimum average rectum dose based on individual anatomy. A preliminary validation study was performed whereby historical plans identified as “optimal” and “sub-optimal” by the local model were replanned in a blinded study by four experienced planners and compared to the original clinical plan to assess whether any improvement in rectum dose was observed. The predictive model was then incorporated into a RayStation script and used as part of the clinical planning process. Planners were asked to use the script during planning to provide a patient specific prediction for optimum average rectum dose and to optimise the plan accordingly. Results Plans identified as “sub-optimal” in the validation study observed a statistically significant improvement in average rectum dose compared to the clinical plan when replanned whereas plans that were identified as “optimal” observed no improvement when replanned. This provided confidence that the local model can identify plans that were suboptimal in terms of rectal sparing. Clinical implementation of the knowledge based planning tool reduced the population-averaged mean rectum dose by 5.6Gy. There was a small but statistically significant increase in total MU and femoral head dose and a reduction in conformity index. These did not affect the clinical acceptability of the plans and no significant changes to other plan quality metrics were observed. Conclusions The knowledge-based planning tool has enabled substantial reductions in population-averaged mean rectum dose for prostate VMAT patients. This suggests plans are improved when planners receive quantitative feedback on plan quality against historical data

Distribution and diversity of alternate hosts of Maruca vitrata Fabricius in three West African countries

The evolution of resistance to the Bacillus thuringiensis (Bt) toxins by insect pests is a major threat to Bt technology. However, the rate of resistance can be slowed with appropriate integrated insect resistance management (IRM) strategies. Surveys were conducted to identify alternate host species for Maruca vitrata (commonly called the legume pod borer or Maruca) that could serve as refuges for Pod-Borer Resistant (PBR) cowpea in three West African countries (Ghana, Nigeria, and Burkina Faso). Survey sites included 25 in northern Ghana, 44 in northern Nigeria, and 52 in north-central and southwestern Burkina Faso. Alternate hosts of Maruca identified from plant species belonging to the Fabaceae family that showed signs of Maruca damage on cowpea tissues were collected and dissected. Larvae that were found during these dissections were reared to adult moths in the laboratory then identified to species. The alternate host plants including species of Crotolaria, Sesbania, Tephrosia, and Vigna were the most frequently encountered among sites and locations. Flowering and podding of these plants overlapped with flowering and podding of the nearby (~200 m) cowpea crop. Abundance of these wild hosts and overlapping flowering patterns with the cowpea crop in most locations have the potential to sustain ample numbers of Bt susceptible Maruca that will mate with possible resistant Maruca and deter resistance development. Further quantitative studies, however, are required from each location to determine if actual Maruca production from alternate hosts is sufficient for a PBR IRM strategy. If verified, this approach would be compatible with the high dose/refuge IRM strategy that includes alternate hosts and non-Bt crops as refuges

Clinical Outcomes by Race and Ethnicity in the Systolic Blood Pressure Intervention Trial (SPRINT): A Randomized Clinical Trial

BACKGROUND: The Systolic Blood Pressure Intervention Trial (SPRINT) showed that targeting a systolic blood pressure (SBP) of ≤ 120 mm Hg (intensive treatment) reduced cardiovascular disease (CVD) events compared to SBP of ≤ 140 mm Hg (standard treatment); however, it is unclear if this effect is similar in all racial/ethnic groups. METHODS: We analyzed SPRINT data within non-Hispanic White (NHW), non-Hispanic Black (NHB), and Hispanic subgroups to address this question. High-risk nondiabetic hypertensive patients (N = 9,361; 30% NHB; 11% Hispanic) 50 years and older were randomly assigned to intensive or standard treatment. Primary outcome was a composite of the first occurrence of a myocardial infarction, acute coronary syndrome, stroke, decompensated heart failure, or CVD death. RESULTS: Average postbaseline SBP was similar among NHW, NHB, and Hispanics in both treatment arms. Hazard ratios (HRs) (95% confidence interval) (intensive vs. standard treatment groups) for primary outcome were 0.70 (0.57–0.86), 0.71 (0.51–0.98), 0.62 (0.33–1.15) (interaction P value = 0.85) in NHW, NHB, and Hispanics. CVD mortality HRs were 0.49 (0.29–0.81), 0.77 (0.37–1.57), and 0.17 (0.01–1.08). All-cause mortality HRs were 0.61 (0.47–0.80), 0.92 (0.63–1.35), and 1.58 (0.73–3.62), respectively. A test for differences among racial/ethnic groups in the effect of treatment assignment on all-cause mortality was not significant (Hommel-adjusted P value = 0.062) after adjustment for multiple comparisons. CONCLUSION: Targeting a SBP goal of ≤ 120 mm Hg compared to ≤ 140 mm Hg led to similar SBP control and was associated with similar benefits and risks among all racial ethnic groups, though NHBs required an average of ~0.3 more medications

Prevalence and etiology of community-acquired pneumonia in immunocompromised patients

Background. The correct management of immunocompromised patients with pneumonia is debated. We evaluated the prevalence, risk factors, and characteristics of immunocompromised patients coming from the community with pneumonia. Methods. We conducted a secondary analysis of an international, multicenter study enrolling adult patients coming from the community with pneumonia and hospitalized in 222 hospitals in 54 countries worldwide. Risk factors for immunocompromise included AIDS, aplastic anemia, asplenia, hematological cancer, chemotherapy, neutropenia, biological drug use, lung transplantation, chronic steroid use, and solid tumor. Results. At least 1 risk factor for immunocompromise was recorded in 18% of the 3702 patients enrolled. The prevalences of risk factors significantly differed across continents and countries, with chronic steroid use (45%), hematological cancer (25%), and chemotherapy (22%) the most common. Among immunocompromised patients, community-acquired pneumonia (CAP) pathogens were the most frequently identified, and prevalences did not differ from those in immunocompetent patients. Risk factors for immunocompromise were independently associated with neither Pseudomonas aeruginosa nor non\u2013community-acquired bacteria. Specific risk factors were independently associated with fungal infections (odds ratio for AIDS and hematological cancer, 15.10 and 4.65, respectively; both P = .001), mycobacterial infections (AIDS; P = .006), and viral infections other than influenza (hematological cancer, 5.49; P < .001). Conclusions. Our findings could be considered by clinicians in prescribing empiric antibiotic therapy for CAP in immunocompromised patients. Patients with AIDS and hematological cancer admitted with CAP may have higher prevalences of fungi, mycobacteria, and noninfluenza viruses