The Contributions of Updating in Working Memory Sub-Processes for Sight-Reading Music Beyond Age and Practice Effects

Music sight reading (SR), has been described as a complex task which involves the simultaneous reading of new non-rehearsed material and performance. Although practice related skill have revealed as the most significant predictor of SR, working memory (WM) processes have shown its relevance in the study of individual differences in SR. We aimed to determine how the updating in WM sub-processes of retrieval/transformation and substitution, could differentially contribute to SR when the effects of age and practice were controlled, and according to the difficulty of the SR tasks and the different indexes of performance measured (SR error, tempo maintenance, rhythmic accuracy, pitch accuracy, articulation accuracy and expressiveness). 131 music students of different ages and levels of instrument knowledge participated in the study. The results showed that whereas the efficiency in the retrieval/transformation sub-processes contributed to SR regardless of the difficulty of the SR tasks, the substitution sub-process also contributed to performance at sight but only in low demanding SR tasks. The results also showed all the updating sub-processes were engaged in SR regarding the proportion of error and rhythmic accuracy. However, both expressiveness and tempo maintenance seemed to be uniquely driven by efficiency in the retrieval/transformation sub-processes, whereas articulation accuracy relied on the efficiency to suppress irrelevant information from WM

La función ejecutiva de actualización y el rendimiento en comprensión lectora y resolución de problemas

In this investigation, the capacity of the working memory (WM) updating executive function to predict individual differences in reading comprehension and problem solving was analyzed in 5th-graders of Primary Education. In addition, we examined whether this relation is direct or mediated by domain-general or domain-specific variables. For this purpose, a series of tasks was administered to assess fluid intelligence, WM information updating, arithmetic abilities, arithmetic problem solving, lexical processing, and reading comprehension in 49 students aged between 10 and 11 years. The results support the idea that updating is an important predictor of reading comprehension, beyond the influence of domainspecific skills and fluid intelligence. In the case of problem solving, our findings confirm that updating plays an important role although, perhaps due to task content, the relation seems to be mediated by fluid intelligence at this developmental stageEsta investigación analizó, en niños de 5º curso de Educación Primaria, la capacidad predictora de la función ejecutiva de actualización de la Memoria Operativa (MO) en las diferencias individuales en comprensión lectora y resolución de problemas aritméticos. Además, se estudió si esta relación es directa o está mediada por variables de dominio general o específico. Con este fin se administró un conjunto de pruebas que evalúan la inteligencia fluida, la actualización de la información en la MO, la competencia aritmética, la resolución de problemas aritméticos, el procesamiento léxico y la comprensión lectora a 49 alumnos con edades comprendidas entre los 10 y 11 años. Los resultados apoyan la idea que la actualización de la MO es un importante predictor de la comprensión lectora, más allá de la influencia de las habilidades de dominio específico y de la inteligencia fluida. En el caso de la resolución de problemas, nuestros hallazgos confirman que la actualización juega un papel importante aunque, en este momento evolutivo, quizá por el propio contenido de la tarea, la relación parece mediada por la inteligencia fluid

Executive functioning profiles and mathematical and reading achievement in Grades 2, 6, and 10

Using a person-centered approach, we aimed to identify different executive functioning profiles to assess heterogeneity across individuals within the same school grade through latent profile analysis. A sample of 150 Grade 2 (7–8 years old), 150 Grade 6 (11–12 years old), and 150 Grade 10 (15–16 years old) children and adolescents were assessed on 11 different executive tasks representative of the three main executive functioning subcomponents (i.e., inhibition, cognitive flexibility, and working memory), fluid intelligence, processing speed, problem-solving, and reading comprehension. Three different executive functioning profiles of different patterns of interactions based on inhibition, cognitive flexibility, and working memory within and between grades were identified. Moreover, these profiles were differentially related to reading comprehension and mathematical achievement. Second, as expected, we did not find these profiles to be associated with sociodemographic variables such as chronological age or sex. Still, fluid intelligence and processing speed were differentially related to the different profiles at each grade. We also found that the executive functioning profiles interacted with each cognitive skill (i.e., fluid intelligence and processing speed) in predicting reading comprehension and math achievement. These findings provide valuable insights for developing preventive and intervention strategies in educationMinisterio de Ciencia e Innovación | Ref. EDU2011-2269

Executive functioning skills and (low) math achievement in primary and secondary school

Schoolchildren with better executive functioning skills achieve better mathematics results. It is less clear how inhibition, cognitive flexibility, and working memory combine to predict mathematics achievement and difficulty throughout primary and secondary school. This study aimed to find the best combination of executive function measures for predicting mathematical achievement in Grades 2, 6, and 10 and to test whether this combination predicts the probability of having mathematical difficulties across school grades even when fluid intelligence and processing speed were included in the models. A total of 426 students—141 2nd graders (72 girls), 143 6th graders (72 girls), and 142 10th graders (79 girls)—were cross-sectionally assessed with 12 executive tasks, one standardized mathematical task, and a standardized test of intelligence. Bayesian regression analyses found various combinations of executive predictors of mathematical achievement for each school grade spanning Grade 2 to measures of cognitive inhibition (negative priming) and cognitive flexibility (verbal fluency); Grade 6 to measures of inhibition: resistance to distractor interference (receptive attention), cognitive flexibility (local–global), and working memory (counting span); and Grade 10 to measures of inhibition: resistance to distractor interference (receptive attention) and prepotent response inhibition (stop signal) and working memory (reading span). Logistic regression showed that the executive models derived from the Bayesian analyses had a similar ability to classify students with mathematical difficulty and their peers with typical achievement to broader cognitive models that included fluid intelligence and processing speed. Measures of processing speed, cognitive flexibility (local–global), and prepotent response inhibition (stop signal) were the main risk factors in Grades 2, 6, and 10, respectively. Cognitive flexibility (verbal fluency) in Grade 2 and fluid intelligence, which was more stable in all three grades, acted as protective factors against mathematical difficulty. These findings inform practical considerations for establishing preventive and intervention proposals.Ministerio de Ciencia e Innovación | Ref. EDU2011-2269

Mental Models in Deductive Reasoning.

Sin resumenSin resume

Unless Reasoning

We report the results of two experiments investigating conditional inferences from conditional unless assertions, such as Juan is not in León unless Nuria is in Madrid. Experiments 1 and 2 check Fillenbaum’s hypothesis about the semantic similarity of unless with if not and only if assertions; both also examine inferential endorsements (Experiment 1) and endorsements and latencies (Experiment 2) of the four logically equivalent conditional formulations: if A then B, if not-B then not-A, A only if B and not- A unless B. The results of these experiments show the similarity of unless and only if, confirming that the representation of both conditionals from the outset probably include two possibilities directionally oriented from B to A; results also confirm the especial difficulty of unless assertions. The implications of the results are discussed in the context of recent psychological and linguistic theories of the meaning of unless.Se presentan los resultados de dos experimentos que investigan las inferencias a partir de enunciados condicionales a menos que, tales como “Juan no está en León a menos que Nuria esté en Madrid”. Los experimentos 1 y 2 comprueban la hipótesis de Fillenbaum sobre la similaridad semántica de los enunciados a menos que con si no y sólo si; ambos experimentos examinan las respuestas inferenciales (Experimento 1) y las respuestas inferenciales y las latencias (Experimento 2) de las cuatro formulaciones condicionales lógicamente equivalentes: si A entonces B, si no-B entonces no A, A sólo si B y no-A a menos que B. Los resultados muestran la similaridad de a menos que y sólo si, confirmando que la representación de ambos condicionales probablemente incluya desde el principio dos posibilidades orientadas direccionalmente desde B a A; los resultados también confirman la dificultad especial de las afirmaciones del tipo a menos que. Las implicaciones de los resultados se comentan en el contexto de las teorías psicológicas y lingüísticas sobre el significado de a menos que

Cognitive, emotional, and social factors promoting psychosocial adaptation: a study of latent profiles in people living in socially vulnerable contexts

IntroductionSocial adaptation is a multifaceted process that encompasses cognitive, social, and affective factors. Previous research often focused on isolated variables, overlooking their interactions, especially in challenging environments. Our study addresses this by investigating how cognitive (working memory, verbal intelligence, self-regulation), social (affective empathy, family networks, loneliness), and psychological (locus of control, self-esteem, perceived stress) factors interact to influence social adaptation.MethodsWe analyzed data from 254 adults (55% female) aged 18 to 46 in economically vulnerable households in Santiago, Chile. We used Latent profile analysis (LPA) and machine learning to uncover distinct patters of socioadaptive features and identify the most discriminating features.ResultsLPA showed two distinct psychosocial adaptation profiles: one characterized by effective psychosocial adaptation and another by poor psychosocial adaptation. The adaptive profile featured individuals with strong emotional, cognitive, and behavioral self-regulation, an internal locus of control, high self-esteem, lower stress levels, reduced affective empathy, robust family support, and decreased loneliness. Conversely, the poorly adapted profile exhibited the opposite traits. Machine learning pinpointed six key differentiating factors in various adaptation pathways within the same vulnerable context: high self-esteem, cognitive and behavioral self-regulation, low stress levels, higher education, and increased social support.DiscussionThis research carries significant policy implications, highlighting the need to reinforce protective factors and psychological resources, such as self-esteem, self-regulation, and education, to foster effective adaptation in adversity. Additionally, we identified critical risk factors impacting social adaptation in vulnerable populations, advancing our understanding of this intricate phenomenon

Viral RNA load in plasma is associated with critical illness and a dysregulated host response in COVID‑19

Background. COVID-19 can course with respiratory and extrapulmonary disease. SARS-CoV-2 RNA is detected in respiratory samples but also in blood, stool and urine. Severe COVID-19 is characterized by a dysregulated host response to this virus. We studied whether viral RNAemia or viral RNA load in plasma is associated with severe COVID-19 and also to this dysregulated response. Methods. A total of 250 patients with COVID-19 were recruited (50 outpatients, 100 hospitalized ward patients and 100 critically ill). Viral RNA detection and quantification in plasma was performed using droplet digital PCR, targeting the N1 and N2 regions of the SARS-CoV-2 nucleoprotein gene. The association between SARS-CoV-2 RNAemia and viral RNA load in plasma with severity was evaluated by multivariate logistic regression. Correlations between viral RNA load and biomarkers evidencing dysregulation of host response were evaluated by calculating the Spearman correlation coefficients. Results. The frequency of viral RNAemia was higher in the critically ill patients (78%) compared to ward patients (27%) and outpatients (2%) (p < 0.001). Critical patients had higher viral RNA loads in plasma than non-critically ill patients, with non-survivors showing the highest values. When outpatients and ward patients were compared, viral RNAemia did not show significant associations in the multivariate analysis. In contrast, when ward patients were compared with ICU patients, both viral RNAemia and viral RNA load in plasma were associated with critical illness (OR [CI 95%], p): RNAemia (3.92 [1.183–12.968], 0.025), viral RNA load (N1) (1.962 [1.244–3.096], 0.004); viral RNA load (N2) (2.229 [1.382–3.595], 0.001). Viral RNA load in plasma correlated with higher levels of chemokines (CXCL10, CCL2), biomarkers indicative of a systemic inflammatory response (IL-6, CRP, ferritin), activation of NK cells (IL-15), endothelial dysfunction (VCAM-1, angiopoietin-2, ICAM-1), coagulation activation (D-Dimer and INR), tissue damage (LDH, GPT), neutrophil response (neutrophils counts, myeloperoxidase, GM-CSF) and immunodepression (PD-L1, IL-10, lymphopenia and monocytopenia). Conclusions. SARS-CoV-2 RNAemia and viral RNA load in plasma are associated with critical illness in COVID-19. Viral RNA load in plasma correlates with key signatures of dysregulated host responses, suggesting a major role of uncontrolled viral replication in the pathogenesis of this disease.This work was supported by awards from the Canadian Institutes of Health Research, the Canadian 2019 Novel Coronavirus (COVID-19) Rapid Research Funding initiative (CIHR OV2 – 170357), Research Nova Scotia (DJK), Atlantic Genome/Genome Canada (DJK), Li-Ka Shing Foundation (DJK), Dalhousie Medical Research Foundation (DJK), the “Subvenciones de concesión directa para proyectos y programas de investigación del virus SARS‐CoV2, causante del COVID‐19”, FONDO–COVID19, Instituto de Salud Carlos III (COV20/00110, CIBERES, 06/06/0028), (AT) and fnally by the “Convocatoria extraordinaria y urgente de la Gerencia Regional de Salud de Castilla y León, para la fnanciación de proyectos de investigación en enfermedad COVID-19” (GRS COVID 53/A/20) (CA). DJK is a recipient of the Canada Research Chair in Translational Vaccinology and Infammation. APT was funded by the Sara Borrell Research Grant CD018/0123 funded by Instituto de Salud Carlos III and co-fnanced by the European Development Regional Fund (A Way to Achieve Europe programme). The funding sources did not play any role neither in the design of the study and collection, not in the analysis, in the interpretation of data or in writing the manuscript