Marine radioecology after the Fukushima Dai-ichi nuclear accident : are we better positioned to understand the impact of radionuclides in marine ecosystems?

© The Author(s), 2017. This is the author's version of the work. It is posted here under a nonexclusive, irrevocable, paid-up, worldwide license granted to WHOI. It is made available for personal use, not for redistribution. The definitive version was published in Science of The Total Environment 618 (2017): 80-92, doi:10.1016/j.scitotenv.2017.11.005.This paper focuses on how a community of researchers under the COMET (CO-ordination and iMplementation of a pan European projecT for radioecology) project has improved the capacity of marine radioecology to understand at the process level the behaviour of radionuclides in the marine environment, uptake by organisms and the resulting doses after the Fukushima Dai-ichi nuclear accident occurred in 2011. We present new radioecological understanding of the processes involved, such as the interaction of waterborne radionuclides with suspended particles and sediments or the biological uptake and turnover of radionuclides, which have been better quantified and mathematically described. We demonstrate that biokinetic models can better represent radionuclide transfer to biota in non-equilibrium situations, bringing more realism to predictions, especially when combining physical, chemical and biological interactions that occur in such an open and dynamic environment as the ocean. As a result, we are readier now than we were before the FDNPP accident in terms of having models that can be applied to dynamic situations. The paper concludes with our vision for marine radioecology as a fundamental research discipline and we present a strategy for our discipline at the European and international levels. The lessons learned are presented along with their possible applicability to assess/reduce the environmental consequences of future accidents to the marine environment and guidance for future research, as well as to assure sustainability of marine radioecology in Europe and globally. This guidance necessarily reflects on why and where further research funding is needed, signalling the way for future investigations.The research leading to this paper has received funding from the European Union's seventh Framework programme (FP7/2007-2013) under grant agreement No. is 604974 (Projects within COMET: Marine Initial Research Activity and The impact of recent releases from the Fukushima nucleaR Accident on the Marine Environment - FRAME). Sampling off Japan has been supported by the Gordon and Betty Moore Foundation, the Deerbrook Charitable Trust and contributions to the WHOI Centre for Marine and Environmental Radioactivity. We acknowledge the JSPS KAKENHI Grant-in-Aid for Scientific Research on Innovative Areas Grant No. 24110005 for supporting in part the activities during the research cruises to the FDNPP area

Introduction to the French GEOTRACES North Atlantic transect (GA01): GEOVIDE cruise

© 2018 Author(s). The GEOVIDE cruise, a collaborative project within the framework of the international GEOTRACES programme, was conducted along the French-led section in the North Atlantic Ocean (Section GA01), between 15 May and 30 June 2014. In this special issue (https://www.biogeosciences.net/special-issue900.html), results from GEOVIDE, including physical oceanography and trace element and isotope cyclings, are presented among 18 articles. Here, the scientific context, project objectives, and scientific strategy of GEOVIDE are provided, along with an overview of the main results from the articles published in the special issue

The evolution of the ventilatory ratio is a prognostic factor in mechanically ventilated COVID-19 ARDS patients

Background: Mortality due to COVID-19 is high, especially in patients requiring mechanical ventilation. The purpose of the study is to investigate associations between mortality and variables measured during the first three days of mechanical ventilation in patients with COVID-19 intubated at ICU admission. Methods: Multicenter, observational, cohort study includes consecutive patients with COVID-19 admitted to 44 Spanish ICUs between February 25 and July 31, 2020, who required intubation at ICU admission and mechanical ventilation for more than three days. We collected demographic and clinical data prior to admission; information about clinical evolution at days 1 and 3 of mechanical ventilation; and outcomes. Results: Of the 2,095 patients with COVID-19 admitted to the ICU, 1,118 (53.3%) were intubated at day 1 and remained under mechanical ventilation at day three. From days 1 to 3, PaO2/FiO2 increased from 115.6 [80.0-171.2] to 180.0 [135.4-227.9] mmHg and the ventilatory ratio from 1.73 [1.33-2.25] to 1.96 [1.61-2.40]. In-hospital mortality was 38.7%. A higher increase between ICU admission and day 3 in the ventilatory ratio (OR 1.04 [CI 1.01-1.07], p = 0.030) and creatinine levels (OR 1.05 [CI 1.01-1.09], p = 0.005) and a lower increase in platelet counts (OR 0.96 [CI 0.93-1.00], p = 0.037) were independently associated with a higher risk of death. No association between mortality and the PaO2/FiO2 variation was observed (OR 0.99 [CI 0.95 to 1.02], p = 0.47). Conclusions: Higher ventilatory ratio and its increase at day 3 is associated with mortality in patients with COVID-19 receiving mechanical ventilation at ICU admission. No association was found in the PaO2/FiO2 variation

Clustering COVID-19 ARDS patients through the first days of ICU admission. An analysis of the CIBERESUCICOVID Cohort

Background Acute respiratory distress syndrome (ARDS) can be classified into sub-phenotypes according to different inflammatory/clinical status. Prognostic enrichment was achieved by grouping patients into hypoinflammatory or hyperinflammatory sub-phenotypes, even though the time of analysis may change the classification according to treatment response or disease evolution. We aimed to evaluate when patients can be clustered in more than 1 group, and how they may change the clustering of patients using data of baseline or day 3, and the prognosis of patients according to their evolution by changing or not the cluster.Methods Multicenter, observational prospective, and retrospective study of patients admitted due to ARDS related to COVID-19 infection in Spain. Patients were grouped according to a clustering mixed-type data algorithm (k-prototypes) using continuous and categorical readily available variables at baseline and day 3.Results Of 6205 patients, 3743 (60%) were included in the study. According to silhouette analysis, patients were grouped in two clusters. At baseline, 1402 (37%) patients were included in cluster 1 and 2341(63%) in cluster 2. On day 3, 1557(42%) patients were included in cluster 1 and 2086 (57%) in cluster 2. The patients included in cluster 2 were older and more frequently hypertensive and had a higher prevalence of shock, organ dysfunction, inflammatory biomarkers, and worst respiratory indexes at both time points. The 90-day mortality was higher in cluster 2 at both clustering processes (43.8% [n = 1025] versus 27.3% [n = 383] at baseline, and 49% [n = 1023] versus 20.6% [n = 321] on day 3). Four hundred and fifty-eight (33%) patients clustered in the first group were clustered in the second group on day 3. In contrast, 638 (27%) patients clustered in the second group were clustered in the first group on day 3.Conclusions During the first days, patients can be clustered into two groups and the process of clustering patients may change as they continue to evolve. This means that despite a vast majority of patients remaining in the same cluster, a minority reaching 33% of patients analyzed may be re-categorized into different clusters based on their progress. Such changes can significantly impact their prognosis

LIMENES. The terminology of the Mediterranean ports of the Roman Empire as documented in the literary sources [In two volumes]

This research forms part of the Portus Limen Project, which investigates Mediterranean port networks in the Roman Empire. The aim of my research is to investigate the precise semantic and pragmatic implications of the Greek and Latin terms referring to ports or anchorages, especially in relation to one another: what does each harbour form require? Where is it located? What are its singularities in relation to other harbour forms?My research represents an ontological approach to the study of the Greek and Roman port terminology. A literature review is included, where I discuss the relevant modern research methods. However, this review appears twofold, due to the novelty of combining linguistics research with archaeological finds – two disciplines that are rarely combined with one another. Next, I describe my methodology, based on text mining, decomponential analysis and prototype theory applied to ancient Greek and Latin texts as the only direct testimonies of speech acts in those languages. This leads me to the exposition of all relevant data as far as possible for the period and for the space chosen. I discuss in the first place the usage of each harbour term in isolation in order to seek its prototype. Secondly, I include two case-studies in order to verify if the conclusions reached in the theoretical discussion do apply in the realities on land, and how the different harbour terms co-exist and interact with one another by means of particular sites. Finally, I provide further discussion on the ontological relations between different port terms. In the end, I hope I am offering satisfactory conclusions on the semantics and pragmatics as to the usage of ancient Greek and Latin harbour terms, as well as some ideas for future work

Kothon, cothon et ports creusés

According to ancient literature, Kothon is the name given to the late Punic ports of Carthage, a particular type of vase and a type of harbour. Ancient definitions of a type of port seem to describe an artificially excavated basin, and this characteristic appears regularly within archaeological literature. However, if the ancient sources are examined closely, the association between Kothon and dug basin is not clear. This paper aims to analyse the sources related to the Kothon and to propose a new definition of the term

Radionuclides as Ocean Tracers

75 pagesRadionuclides, both from natural and anthropogenic origin, are powerful ocean tracers that provide key information on fluxes, pathways and time scales of marine processes. Their added value compared to hydrographic parameters (e.g., temperature and salinity) relies either on their known rates of radioactive decay and production or on their time-variable releases from sources. Both aspects introduce a temporal dimension that allows quantifying rates or time scales of marine processes. Their wide range of half-lives and historical inputs, together with their physicochemical characteristics allow tracing a broad spectrum of marine processes. This chapter aims at providing an overview of the application of radionuclides as tracers of ocean processes. The chapter is structured in four sections: The first part reviews the main principles of radioactivity and the origin of radionuclides. The second section introduces the key aspects that allow using radionuclides as ocean tracers, followed by (third section) three real and contemporary instructive examples that cover different marine processes and require radionuclides with specific properties: i) thorium-234/uranium-238 (234Th/238U) pair to quantify the biological pump, ii) radium (Ra) isotopes to estimate the magnitude of submarine groundwater discharge, and iii) iodine-129 (129I) to investigate the large-scale ocean circulation. Finally, this chapter provides a summary of the different methods and techniques used to measure radionuclides in seawaterPeer reviewe

High Precision 14C Analysis in Small Seawater Samples

ISSN:0033-822

236U, 237Np and 239,240Pu as complementary fingerprints of radioactiveeffluents in the western Mediterranean Sea and in the Canada Basin (Arctic Ocean)

The aim of this study was to assess the potential of combining the conservatively behaving anthropogenic radionuclides 236U and 237Np to gain information on the origin of water masses tagged with liquid effluents from Nuclear Reprocessing Plants. This work includes samples collected from three full-depth water columns in two areas: i) the Arctic Ocean, where Atlantic waters carry the signal of Sellafield (United Kingdom) and La Hague (France) nuclear reprocessing facilities; and ii) the western Mediterranean Sea, directly impacted by Marcoule reprocessing plant (France). This work is complemented by the study of the particle-reactive Pu isotopes as an additional fingerprint of the source region. In the Canada Basin, Atlantic waters showed the highest concentrations and 237Np/236U ratios in agreement with the estimated values for North Atlantic waters entering the Arctic Ocean and tagged with the signal of European Nuclear Reprocessing Plants. These results may reflect the impact of the documented releases for the 1990s. In the Mediterranean Sea, an excess of 236U presumably caused by Marcoule is reflected in the lower 237Np/236U ratios compared to the Global Fallout signal in all the studied samples. On the contrary, the 239,240Pu profiles were mainly governed by the Global Fallout. The impact of Marcoule as a local source is further corroborated when comparing the temporal evolution of these ratios between 2001 and 2013. The lowest 237Np/236U ratios observed in 2001 at the surface reflect a previous local input that is no longer observed in 2013 as it had been homogenized through the whole water column. This work presents the use of 237Np as a new ocean tracer. A more accurate characterization of the main sources is still needed to optimize the use of 236U-237Np as a new tool to understand transient oceanographic processes.This work has been financed from the projects FIS2015-69673-P and PGC2018-094546-B-I00, provided by the Spanish Government (Ministerio de Economía y Competitividad and Ministerio de Ciencia, Innovación y Universidades) and by the U.S. National Science Foundation through award OCE 1439319. This work was partially funded by Fundación Cámara Sevilla through a Grant for Graduate Studies. The IAEA is grateful to the Government of the Principality of Monaco for the support provided to its Environment Laboratories.Peer reviewe